Artery Research
2994 articles
Conference Abstract
3.1 STRAIN DISCONTINUITIES IN CAROTID ATHEROSCLEROTIC PLAQUES – A NOVEL MARKER FOR PLAQUE VULNERABILITY?
Tim Vonk, Evelien Hermeling, Floris Schreuder, Werner Mess, Eline Kooi
Pages: 71 - 71
Objective: Rupture of atherosclerotic plaques is ultimately a biomechanical event. We aim to develop and validate a novel method using ultrasound radiofrequency (RF) measurements to determine intraplaque inhomogeneities in the strain distribution with a high axial resolution which may identify rupture-prone...
Conference Abstract
P61 PSYCHOLOGICAL DETERMINANTS OF TARGET ORGAN DAMAGE IN HYPERTENSIVE PATIENTS: FOCUS ON TYPE A PERSONALITY AND LEFT VENTRICULAR MASS INDEX
Andrea Greco, Alessandro Maloberti, Paola Sormani, Giulia Colombo, Luca Giupponi, Stephan Laurent, Pierre Boutouyrie, Massimo D’Addario, Anna Maria Annoni, Antonella Moreo, Cristina Giannattasio, Patrizia Steca
Pages: 71 - 71
Background: Increased Left Ventricular Mass Index (LVMI) is a well known risk factor for cardiac morbidity and mortality. Furthermore, it is widely recognized that clinical evolution and progression of established CV diseases are related to a range of psychological characteristics, which may partially...
Conference Abstract
9.11 VASCULAR PHENOTYPING BY MEANS OF VERY HIGH-RESOLUTION ULTRASOUND IMAGING: A FEASIBILITY ANALYSIS
N. Di Lascio, R.M. Bruno, V. Gemignani, E. Bianchini, L. Ghiadoni, F. Faita
Pages: 71 - 71
Background: The study of medium and small-size arteries might be useful in the characterization of vascular adaptation, remodeling and wall ultrastructure modifications occurring with aging and in the presence of cardiovascular risk factors. However, to date, these districts have not been extensively...
Conference Abstract
P.080 AGE-RELATED CAROTID REMODELING AND WALL SHEAR RATE: INSIGHTS FROM A NOVEL MULTIGATE DOPPLER SYSTEM FOR INTEGRATED EVALUATION OF FLOW VELOCITY PROFILE AND DIAMETERS
E. Malshi, A. Dallai, T. Morganti, G. Bambi, M. Kozàkovà, S. Ricci, C. Morizzo, P. Tortoli
Pages: 71 - 71
Conference Abstract
2.7 FITNESS MODIFIES THE ASSOCIATION BETWEEN EXERCISE BLOOD PRESSURE AND LEFT-VENTRICULAR MASS IN ADOLESCENCE
Zhengzheng Huang, Ricardo Fonseca, James Sharman, Nish Chaturvedi, George Smith, Deborah Lawlor, Laura Howe, Chloe Park, Alun Hughes, Martin Schultz, Martin Schultz
Pages: 71 - 71
Objective: Exaggerated exercise blood pressure (BP) is associated with higher left-ventricular mass index (LVMI). Paradoxically, exercise BP and LVMI may be higher with greater fitness, but underlying factors are poorly understood. This study aimed to determine the influence of fitness on exercise BP...
Conference Abstract
P62 BLOOD PRESSURE LOWERING HALTS CAROTID ARTERY STIFFENING IN HYPERTENSIVE PATIENTS: THE CATOD STUDY
Siske Bos, Rosa Maria Bruno, Bart Spronck, Maarten Heusinkveld, Stefano Taddei, Lorenzo Ghiadoni, Koen Reesink
Pages: 71 - 72
Background: We anticipate that in vascular outpatients followed over time, measured changes in arterial stiffness will be the multifactorial result of pressure-dependence, ageing- related degeneration, wall stress homeostasis, and medical treatment. Carotid ultrasound enables assessment of carotid pulse...
Conference Abstract
10.1 OPTIMAL AUTOMATED UNOBSERVED OFFICE BLOOD PRESSURE PROTOCOL: ONLY 6-MINUTES AND TWO READINGS MAY BE NEEDED
Myles Moore, Nathan Dwyer, Ella Hoban, Mark Nelson, Dean Picone, Martin Schultz, James Sharman
Pages: 71 - 71
Background: Automated office blood pressure (AutoBP) involving repeated, unobserved blood pressure (BP) readings during one clinic visit provides a practical alternative to daytime ambulatory blood pressure (ABP). However, the number of reading taken and measurement duration have varied across previously...
Conference Abstract
P.081 VALIDITY OF THE ONE-THIRD RULE TO CALCULATE MEAN ARTERIAL PRESSURE
D. Mahieu, E. Rietzschel, M. De. Buyzere, T. Gillebert, P. Segers, L Van Bortel
Pages: 71 - 71
Conference Abstract
2.8 RELATIONSHIPS BETWEEN ADIPOSITY AND LEFT VENTRICULAR FUNCTION IN ADOLESCENTS: MEDIATION BY BLOOD PRESSURE AND OTHER CARDIOVASCULAR MEASURES
Hannah Taylor, Alun D. Hughes, Abigail Fraser, Laura Howe, George Davey Smith, Debbie Lawlor, Nishi Chaturvedi, Chloe Park
Pages: 71 - 72
Introduction: Increased adiposity is associated with poorer left ventricular (LV) function but the mediating role of blood pressure (BP) and other cardiovascular measures is unknown. We investigated the roles of potential mediators in adolescents in a UK birth cohort, the Avon Longitudinal Study of Parents...
Conference Abstract
10.2 EFFECTS OF INTER-ARM DIFFERENCES OF BRACHIAL SYSTOLIC BLOOD PRESSURE ON THE DERIVATION OF AORTIC SYSTOLIC PRESSURE
Alberto Avolio, Davis Theobald, Mitchel Cook, Karen Peebles, Mark Butlin
Pages: 71 - 71
Background: Inter-arm differences in brachial systolic blood pressure (SBP) should not theoretically translate to differences in calculated aortic SBP, there being only a single value of aortic blood pressure (BP) at any time.
Methods: This study assessed seated brachial and derived aortic SBP in 79...
Conference Abstract
P.082 BENEFICIAL EFFECT OF LAUGHTER ON ARTERIAL STIFFNESS AND WAVE REFLECTIONS: THE ROLE OF INFLAMMATION, ENDOTHELIAL FUNCTION AND OXIDATIVE STATUS
P. Xaplanteris, C. Vlachopoulos, K. Baou, C. Vasiliadou, I. Dima, C. Stefanadis
Pages: 71 - 72
Conference Abstract
10.3 USE OF MICROLIFE BP WATCH IS A FEASIBLE APPROACH TO DETERMINE INTER-ARM BLOOD PRESSURE DIFFERENCES IN A CLINICAL SETTING
Christoffer Krogager, Esben Laugesen, Niklas B. Rossen, Per L. Poulsen, Mogens Erlandsen, Klavs W. Hansen
Pages: 71 - 72
Aim: The aim of this study is to evaluate the feasibility of Microlife Watch BP for measuring bilateral blood pressure (BP) in a clinical setting.
Method: 339 patients (85% diabetic) scheduled for ambulatory blood pressure monitoring at the outpatient clinic for endocrinology, Silkeborg Regional Hospital,...
Research Article
Arterial Stiffness, Central Blood Pressure, and Cardiac Biomarkers in Long-Distance Walkers
Wátila Moura Sousa, Maicon Borges Euzébio, Priscila Valverde de Oliveira Vitorino, Ana Luiza Sousa, Thiago Veiga Jardim, Paulo Cesar Veiga Jardim, Antonio Coca, Gonzalo Grazioli, Eduardo Costa Duarte Barbosa, Weimar Kunz Sebba Barroso
Pages: 71 - 76
The cardiovascular effects of long-distance and -duration activities and their relationship with arterial stiffness and cardiac biomarkers are still unclear. This study aimed to assess arterial stiffness and Central Blood Pressure (cBP) and correlate them with cardiac biomarkers in long-distance walkers...
Research Article
Vascular characteristics in patients with resistant hypertension and type-II-diabetes mellitus
Trine Koustrup Soender, Jacob Eifer Møller, Brian Bridal Løgstrup, Jess Lambrechtsen, Jørgen Hangaard, Kenneth Egstrup
Pages: 71 - 77
Background: Resistant hypertension is presumed to be common in patients with type-II-diabetes mellitus (type-II-DM) and arterial stiffness has been proposed to play a major role in the development hereof. Our objective with this study was to examine differences in vascular characteristics in patients...
Research Article
Addressing the Unmet Needs of Measuring Vascular Ageing in Clinical Practice–European COoperation in Science and Technology Action VascAgeNet
Rachel Emma Climie, Christopher Clemens Mayer, Rosa Maria Bruno, Bernhard Hametner
Pages: 71 - 75
Cardiovascular Disease (CVD) is the leading cause of morbidity and mortality worldwide, regardless of gender, ethnicity or income. Evidence that vascular age, as opposed to chronological age, is better related to the prognosis of CVD is convincing. Despite recent technological advances for the measurement...
Conference Abstract
P.083 COMPARISON OF LOCAL CAROTID AND AORTIC STIFFNESS PARAMETERS IN MILD ESSENTIAL HYPERTENSIVE PATIENTS
C. Giannarelli, E. Bianchini, K. Raimo, L. Landini, F. Faita, V. Gemignani, M. Demi, L. Ghiadoni
Pages: 72 - 72
Conference Abstract
P63 CAN BRAQUIAL OSCILLOMETRY IDENTIFY PREHYPERTENSION AMONG NORMOTENSIVE SUBJECTS?
Enrique Rodilla, Manuel Adell, Vicente Giner, Zeneida Perseguer, Jose Maria Pascual, Maria Teresa Climent
Pages: 72 - 72
Background and objective: Arterial stiffness (AS) reflects vascular damage. Our objective was to determine 1) the frequency of AS in community pharmacies, 2) if subjects with AS identified by brachial oscillometry have more CV risk factors than normal subjects, and 3) if the prevalence of AS varies upon...
Conference Abstract
10.4 COMPARISON OF BLOOD PRESSURE VARIABILITY CALCULATED FROM PERIPHERAL AND DERIVED AORTIC BLOOD PRESSURE
Zahra Kouchaki, Mark Butlin, Ahmad Qasem, Alberto Avolio
Pages: 72 - 72
Background: Systolic blood pressure variability (SBPV), conventionally calculated from peripheral sites such as the arm or finger, may be of more utility when computed from central aortic values, as this has greater applicability to the heart and the baroreceptor function, due to central location of...
Conference Abstract
P.084 VISCERAL ADIPOSITY AS THE MAIN DETERMINANT OF CAROTID STIFFNESS IN A HEALTHY POPULATION WITH A WIDE BMI AND AGE RANGE: EVIDENCE FROM AN ECHO-TRACKING APPROACH
E. Guerra, E. Malshi, C. Morizzo, M. Kozakova, S. Camastra, E. Muscelli, C. Palombo, E. Ferrannini
Pages: 72 - 72
Conference Abstract
3.2 RESERVOIR PRESSURE INTEGRAL IS INDEPENDENTLY ASSOCIATED WITH THE REDUCTION IN RENAL FUNCTION IN AN OLDER POPULATION
Kunihiko Aizawa, Francesco Casanova, David M. Mawson, Kim M. Gooding, W. David Strain, Phillip E. Gates, Gerd Östling, Faisel Khan, Helen M. Colhoun, Carlo Palombo, Kim H. Parker, Jan Nilsson, Angela C. Shore, Alun D. Hughes
Pages: 72 - 73
Background: Central haemodynamic parameters derived from reservoir pressure analysis (RPA-parameters) exhibit prognostic utility. Alterations in reservoir function could have an unfavourable influence on target organs, such as the kidneys. We determined in older adults whether these RPA-parameters would...
Conference Abstract
P64 ARTERIAL STIFFNESS AND PULSE PRESSURE AMPLIFICATION IN ADULTS WITH ISOLATED SYSTOLIC HYPERTENSION
Rosa Maria Bruno, Francesco Faggioni, Daniele Simone, Stefano Taddei, Ugo Faraguna, Lorenzo Ghiadoni
Pages: 72 - 72
Background/aim: ISH is usually considered more prevalent in aged individuals and associated to increased large artery stiffness. This study is aimed at identifying determinants of ISH in adult individuals.
Methods: 20 individuals <60 years, referred to the Outpatient Hypertension Unit for high blood...
Conference Abstract
10.5 COMPARISON OF ARTERIAL STIFFNESS ASSESSED BY POPMÈTRE® WITH ARTERIAL STIFFNESS ASSESSED BY APPLANATION TONOMETRY: A CLINICAL STUDY
Hasan Obeid, Hakim Khettab, Pierre Boutouyrie, Stephane Laurent, Magid Hallab
Pages: 72 - 72
Background: Large artery stiffness is recognized as a strong, independent marker of cardiovascular risk, mainly through aortic pulse wave velocity (PWV). pOpmètre® is a new non-invasive method, which estimates aortic PWV through finger-toe (FT) wave analysis. In a previous study, Alivon et al. have shown...
Conference Abstract
P.085 METABOLIC SYNDROME AND VASCULAR ALTERATIONS IN NORMOTENSIVE PATIENTS AT RISK OF DIABETES MELLITUS
C. Giannarelli, Y. Plantinga, L. Ghiadoni, G. Penno, A. Salvetti, S. Del Prato
Pages: 72 - 72
Conference Abstract
P65 GENDER DIFFERENCES OF AORTIC WAVE REFLECTION AND INFLUENCE OF MENOPAUSE ON CENTRAL BLOOD PRESSURE IN PATIENTS WITH ARTERIAL HYPERTENSION
Valeria Costa-Hong, Henrique Muela, Thiago Macedo, Alan Sales, Luiz Bortolotto
Pages: 72 - 72
Background: Evidences suggest that central hemodynamics indexes are independent predictors of future cardiovascular events and all-cause mortality. Multiple factors have been pointed to have potential influence on central aortic function: height, heart rate, left ventricular ejection duration and blood...
Conference Abstract
10.6 VARIATION OF THE ASYMPTOTIC DIASTOLIC PRESSURE WITH DIFFERENT FITTING TECHNIQUES IN HEALTHY HUMANS
Nicola Pomella, Christina Kolyva, Ernst Rietzschel, Patrick Segers, Ashraf W. Khir, Madalina Negoita
Pages: 72 - 72
Background: Reservoir-wave model assumes the measured pressure (Pm) consists of two additive components: reservoir (Pr) and excess pressure (Pex)1–2. Calculation of Pr requires fitting the diastolic decay of Pm for calculating parameters P∞ (asymptotical value) and b (time constant)1. However, there...
Conference Abstract
P.088 ENDOTHELIAL DYSFUNCTION AND ITS CORRECTION IN SUBCLINICAL THYROTOXICOSIS
A.J. Babenko, A.V. Liscer, M.I. Cadinskaya
Pages: 72 - 73
Conference Abstract
10.7 NON-INVASIVE ESTIMATION OF CENTRAL SYSTOLIC PRESSURE: A COMPARISON BETWEEN RADIAL ARTERY TONOMETRY AND A NEW DIRECT CENTRAL BLOOD PRESSURE ESTIMATION METHOD (DCBP)
Denis Chemla, Sandrine Millasseau, Edmund Lau, Nathalie Richard, Pierre Attal, Mabrouk Brahimi, Alain Nitenberg
Pages: 72 - 73
Background: We have developed a new proprietary method (DCBP® Direct Central Blood Pressure) to estimate central systolic blood pressure (cSBP) directly from peripheral pressure. In a previous meta-analysis of published high-fidelity pressure studies with simultaneous aortic and brachial pressure recordings,...
Research Article
Applanation tonometry for evaluation of the haemodynamic response to the active orthostatic test
Rene Mileva-Popova, Nikolay Stoynev, Nina Belova
Pages: 72 - 82
Background: Our study was aimed at the assessment of the age-specific hemodynamic response to the active orthostatic test (OT).
Methods: Two groups (60-Y/O and 20-Y/O) were subjected to OT (three 5-minute periods: baseline supine, upright standing, recovery supine). Continuous electrocardiogram was...
Research Article
Retinal arteriolar and venular phenotypes in a Flemish population: Reproducibility and correlates
Yan-Ping Liu, Tom Richart, Yu Jin, Harry A. Struijker-Boudierc, Jan A. Staessen
Pages: 72 - 79
Background: To our knowledge, no previous study assessed the reproducibility of non-mydriatic imaging of retinal microvessels using state-of-the-art Bland and Altman statistics.
Methods: In 194 subjects randomly selected from a Flemish population, we post-processed retinal images (Canon Cr-DGi) using...
Conference Abstract
P.089 INFLUENCE OF A SUBCLINICAL THYROTOXICOSIS ON HEART IN VARIOUS AGE-GRADES
E.N. Grineva, A.J. Babenko, N.V. Vahrameeva
Pages: 73 - 73
Conference Abstract
3.3 ROLE OF ARTERIAL STIFFNESS AND BLOOD PRESSURE VARIABILITY IN THE DEFINITION OF SHATS (SYSTEMIC HEMODYNAMIC ATHEROTHROMBOTIC SYNDROME)
Angelo Scuteri, Valentina Rovella, Danilo Alunni Fegatelli, Manfredi Tesauro, Marco Gabriele, Nicola Di Daniele
Pages: 73 - 73
Background: CV risk exponentially increases as the number of damaged organs increases The Systemic Hemodynamic Atherosclerotic Syndrome (SHATS) represents a novel conceptualization of the CV continuum focusing on simultaneous multi-organ alteration. This is the first study operationally defining SHATS...
Conference Abstract
P66 ASSOCIATION BETWEEN URINARY SODIUM EXCRETION, ENDOTHELIAL FUNCTION AND ARTERIAL STIFFNESS IN NON-DIABETIC HYPERTENSIVE PATIENTS
Michelle Cunha, Ana Rosa Cunha, Bianca Cristina Marques, Jenifer D’El-Rei, Samanta Mattos, Ronaldo Gismondi, Wille Oigman, Mario Neves
Pages: 73 - 73
Background: High salt intake has been associated with structural and functional vascular changes.1
Objective: To correlate urinary sodium excretion with endothelial function and arterial stiffness in non-diabetic hypertensive patients.
Methods: Cross-sectional study with non-diabetic hypertensive patients,...
Conference Abstract
10.8 SYSTOLIC AORTIC PRESSURE DERIVED FROM DIFFERENT CALIBRATION METHODS IN THE GENERAL POPULATION
Siegfried Wassertheurer, Bernhard Hametner, Christopher Mayer, Ahmed Hafez, Thomas Weber
Pages: 73 - 73
Background: There is recent evidence from different research groups that accuracy [1] and prognostic value [2,3,4] of systolic aortic pressure significantly depends on the method of calibration. Although these results consistently show superiority of mean pressure calibration (aSBP2) over both, traditional...
Conference Abstract
P.090 BASELINE PULSE WAVE VELOCITY IS AN INDEPENDENT PREDICTOR OF THE BLOOD PRESSURE REDUCTION AND EFFECTIVE BLOOD PRESSURE CONTROL: THE REASON STUDY
A.D. Protogerou, J. Blacher, M.E. Safar
Pages: 73 - 73
Conference Abstract
3.4 A CLINICAL SCORE TO PREDICT ELEVATED ARTERIAL STIFFNESS: DERIVATION AND VALIDATION IN 3,943 HYPERTENSIVE PATIENTS
Panagiotis Xaplanteris, Charalambos Vlachopoulos, Athanasios Protogerou, Konstantinos Aznaouridis, Dimitris Terentes-Printzios, Antonis Argyris, Nikolaos Tentolouris, Petros Sfikakis, Dimitris Tousoulis
Pages: 73 - 73
Purpose/Background/Objectives: Aortic stiffness assessed by carotid-femoral pulse wave velocity (PWV) is an important predictor to gauge the overall risk of hypertensive patients; nonetheless, it is underutilized in everyday practice. We derived a simple scoring system based on clinical variables that...
Conference Abstract
P73 THE ASSESSMENT OF PULMONARY ARTERY STIFFNESS IN COPD USING CARDIAC MRI THE Q/A METHOD
Nichola Gale, Sujoy Saikia, Margaret Munnery, John Cockcroft
Pages: 73 - 73
Background: Pulmonary artery distensibility and pulsatility has been studied in patients with COPD using cardiac MRI (CMRI) (1). However, pulmonary artery pulse wave velocity (PA- PWV) using ‘QA’ method (2) in CMRI has not been studied in this population. We hypothesized that patients with COPD have...
Conference Abstract
10.9 ARTERIAL STIFFNESS INDEX BETA AND CARDIO-ANKLE VASCULAR INDEX INHERENTLY DEPEND ON BLOOD PRESSURE, BUT CAN BE READILY CORRECTED
Bart Spronck, Alberto Avolio, Isabella Tan, Mark Butlin, Koen Reesink, Tammo Delhaas
Pages: 73 - 73
Objectives: Arterial stiffness index β and cardio-ankle vascular index (CAVI) are widely accepted to quantify the blood pressure (BP)-independent, intrinsic exponent (β0) of the BP-diameter relationship. CAVI and β assume an exponential relationship between pressure (P) and diameter (d). We aim (1) to...
Conference Abstract
P.091 A PATIENT SPECIFIC WAVE PROPAGATION MODEL OF THE UPPER LIMB
C.A.D. Leguy, E.M.H. Bosboom, A.P.G. Hoeks, F.N. Van de Vosse
Pages: 73 - 73
Conference Abstract
3.5 CUFF BLOOD PRESSURE IS PROGRESSIVELY MORE BIASED WITH INCREASING AGE: INDIVIDUAL PARTICIPANT LEVEL ANALYSIS FROM THE INSPECT CONSORTIUM
Dean Picone, Martin Schultz, Petr Otahal, Ahmed Al-Jumaily, J. Andrew Black, Willem Bos, Chen-Huan Chen, Hao-Min Chen, Antoine Cremer, Nathan Dwyer, Ricardo Fonseca Diaz, Brian Gould, Alun Hughes, Hack-Lyoung Kim, Peter Lacy, Esben Laugesen, Sandy Muecke, Nobuyuki Ohte, Stefano Omboni, Christian Ott, Xiaoqing Peng, Telmo Pereira, Giacomo Pucci, Philip Roberts-Thomson, Niklas Rossen, Roland Schmieder, Velandai Srikanth, Ralph Stewart, George Stouffer, Daisuke Sueta, Kenji Takazawa, Ji-Guang Wang, Thomas Weber, Berend Westerhof, Bryan Williams, Hirotsugu Yamada, Eiichiro Yamamoto, James Sharman
Pages: 73 - 74
Objectives: Accurate blood pressure (BP) measurement is critical for appropriate hypertension diagnosis and management. Aortic BP represents pressure loading on vital organs and this can be approximated using upper arm cuff BP. With advancing age, cuff systolic BP (SBP) increases and diastolic BP (DBP)...
Conference Abstract
P74 WALL SHEAR RATE AND BRACHIAL ARTERY FLOW-MEDIATED DILATORY RESPONSE BETWEEN HEALTHY YOUNG AND OLDER POPULATIONS USING MULTI-GATE SPECTRAL DOPPLER ULTRASOUND
Kunihiko Aizawa, Sara Sbragi, Alessandro Ramalli, Piero Tortoli, Francesco Casanova, Carmela Morizzo, Clare Thorn, Angela Shore, Phillip Gates, Carlo Palombo
Pages: 73 - 73
Background: Ageing is associated with an impaired brachial artery flow-mediated dilatation (FMD) response and a reduced wall shear rate (WSR) stimulus may contribute to this response. However, a detailed analysis of the WSR-FMD response is lacking due to inherent difficulties of WSR estimation near the...
Conference Abstract
P.092 EXERCISE IS A PROTECTIVE FACTOR AGAINST ARTERIAL STIFFNESS RESULTS FROM THE MONICA/KORA AUGSBURG STUDY
M.R.P. Markus, J. Stritzke, W. Lieb, B. Mayer, A. Luchner, A. Döring, U. Keil, H.W. Hense, H. Schunkert
Pages: 73 - 74
Letter to Editor
Predictors of amputation above the knee in Brazilian health system
Wagner Ramos Borges, Aquiles Tadashi Ywata de Carvalho, Roque Aras Junior
Pages: 73 - 74
Research Article
24-h ambulatory pulse wave velocity and central blood pressure in type 2 diabetes
C. Krogager, N.B. Rossen, E. Laugesen, S.T. Knudsen, P.L. Poulsen, K.W. Hansen
Pages: 73 - 79
Background: Pulse wave analysis from a brachial cuff permits ambulatory measurements of pulse wave velocity (PWV) and central blood pressure parameters. The diurnal variation of PWV in type 2 diabetes is unknown.
Methods: We evaluated the Arteriograph24 which is a brachial cuff based equipment for estimating...
Research Article
Wall shear stress revisited
Robert S. Reneman, Hans Vink, Arnold P.G. Hoeks
Pages: 73 - 78
In vivo measurements of wall shear stress (WSS), a determinant of endothelial cell function and gene expression, have shown that theoretical assumptions regarding WSS in the arterial system and its calculation are invalid. In humans mean WSS varies along the arterial tree and is higher in the carotid...
Conference Abstract
P.093 ROLE OF HEART FAILURE ETIOLOGY ON ARTERIAL WAVE REFLECTION IN HEART TRANSPLANT RECIPIENTS: RELATION WITH CIRCULATING C-REACTIVE PROTEIN
G.L. Pierce, R.S. Schofield, W.W. Nichols, J.A. Hill, R.W. Braith
Pages: 74 - 74
Conference Abstract
3.6 BLOOD PRESSURE REDUCTION IS THE MAIN DETERMINANT OF THE DE-STIFFENING EFFECT OF ANTIHYPERTENSIVE TREATMENT: A META-REGRESSION ANALYSIS AND COMPARISON WITH ACUTE MODULATION OF TRANSMURAL PRESSURE
Andrii Boguslavskyi, Benyu Jiang, Haotian Gu, Yao Lu, Marina Cecelja, Phil Chowienczyk
Pages: 74 - 74
Background: Pulse wave velocity (PWV) is independent predictor of cardiovascular outcomes. Antihypertensive treatment reduces PWV, but it is unknown whether this results from an unloading of stiffer elements in the arterial wall or a structural change in the wall.
Methods: To distinguish between these...
Conference Abstract
P75 SIGNS OF ACCELERATED CAROTID ATHEROSCLEROSIS IN EARLY TYPE 2 DIABETES ASSESSED BY MAGNETIC RESONANCE IMAGING
Esben Laugesen, Pernille Høyem, Samuel Thrysøe, Esben Hansen, Anders Mikkelsen, Bill Kerwin, L. Poulsen Per, K. Hansen Troels, Y. Kim Won
Pages: 74 - 74
Background: Ischemic stroke from carotid plaque embolism remains a major cause of morbidity and mortality in patients with type 2 diabetes (T2DM). However, the effect of T2DM on early carotid plaque burden and composition is sparsely elucidated. We assessed carotid plaque composition by carotid magnetic...
Conference Abstract
10.10 HEMODYNAMIC CORRELATES OF THE LEFT VENTRICULAR MEAN EJECTION PRESSURE: A CAROTID TONOMETRY STUDY
Mathieu Jozwiak, Sandrine Millasseau, Jean-Louis Teboul, Jean-Emmanuel Alphonsine, Francois Depret, Nathalie Richard, Pierre Attal, Xavier Monnet, Denis Chemla
Pages: 74 - 74
Background: The systemic arterial load imposed to the left ventricle (LV) is a major determinant of normal/abnormal cardiovascular function. The LV mean ejection pressure (LVMEP) is the best estimate of load faced by the LV throughout ejection. The contribution of the steady and pulsatile blood pressure...
Conference Abstract
P.094 CAROTID ATHEROSCLEROSIS ASSOCIATED TO METABOLIC SYNDROME AND ISCHEMIC HEART DISEASE IN HYPERTENSIVE PATIENTS WITH LEFT VENTRICULAR HYPERTROPHY
I. Tasic, D. Lovic, D. Djordjevic, M. Lovic
Pages: 74 - 74
Conference Abstract
3.7 PULSE WAVE VELOCITY IS AN INDEPENDENT RISK FACTOR FOR CARDIOVASCULAR EVENTS, MORTALITY AND DECLINE IN RENAL FUNCTION IN PATIENTS WITH TYPE 1 DIABETES
Tine Willum Hansen, Marie Frimodt-Møller, Simone Theilade, Nete Tofte, Tarun Veer Singh Ahluwalia, Peter Rossing
Pages: 74 - 74
Purpose: The prognostic significance of carotid-femoral pulse wave velocity (cfPWV) remains to be determined in patients with type 1 diabetes (T1D). We investigated the predictive value of cfPWV for various endpoints in T1D.
Methods: At baseline, cfPWV was measured using the SphygmoCor device in 652...
Conference Abstract
P76 PERIPHERAL BLOOD PRESSURE AND STIFFNESS INDEX ESTIMATION USING THE PPG SIGNAL MEASURED WITH THE pOpmètre DEVICE: CALIBRATION WITH THE CUFF BLOOD PRESSURE
Hasan Obeid, Hakim Khettab, Magid Hallab, Stephane Laurent, Pierre Boutouyrie
Pages: 74 - 74
Arterial stiffness may influence the contour of the peripheral pulse, suggesting that contour analysis of the digital volume pulse (DVP) might be used to estimate peripheral blood pressure and a stiffness index (SI).
The objective is to establish a transfer function that estimates the peripheral blood...
Conference Abstract
11.1 ENDOTHELIAL FUNCTION IS IMPAIRED IN WOMEN WHO HAD PRE-ECLAMPSIA
Christian Delles, Catriona Brown, Joanne Flynn, Shona Kerr, David Carty
Pages: 74 - 74
Background: Women with a history of pre-eclampsia (PE) are at higher risk of cardiovascular disease later in life. We evaluated the cardiovascular health of women who had PE in comparison with women who had normotensive pregnancies.
Methods: We assessed heart rate-adjusted augmentation index (AIx SphygmoCor),...
Conference Abstract
P.095 THE DISPARATE EFFECTS OF MICROVASCULAR RAREFACTION AND REDUCED COMPLIANCE ON PROXIMAL HAEMODYNAMICS: INVESTIGATION WITH A MATHEMATICAL AND COMPUTATIONAL MODEL OF THE CIRCULATION
G.A. Vaughan, M.K. Johnson, P.B. Mark, J.M.C. Connell, M.S. Olufsen, N.A. Hill, C.A.R. Sainsbury
Pages: 74 - 74
Conference Abstract
P77 NEAR INFRARED SPECTROSCOPY (NIRS) CAN DETECT DIFFERENCES IN MICROVASCULAR REACTIVE HYPERAEMIA IN THE PRESENCE OF HYPERTENSION
Siana Jones, Chloe Park, Nish Chaturvedi, Alun Hughes
Pages: 74 - 74
Background: Hypertension has adverse effects on microvascular function but there are limited methods that permit non-invasive assessment of the microcirculation in man in vivo. We used Near Infrared Spectroscopy (NIRS) to assess microvascular reactive hyperaemia in skeletal muscle following a short period...
Conference Abstract
11.2 CORONARY ARTERY DISEASE TOPOGRAPHY IN RELATION TO RHEOLOGY OF THE PERIPHERAL SMALL ARTERIES IN MIDDLE AGED ERECTILE DYSFUNCTION MEN
Athanasios Angelis, Nikolaos Ioakimidis, Konstantinos Rokkas, Dimitrios Terentes, Ioanna Gourgouli, Christos Georgakopoulos, Konstantinos Aznaouridis, Charalampos Vlachopoulos, Dimitrios Tousoulis
Pages: 74 - 74
Background: Middle age represents a life period where incidence of cardiovascular events typically augments. Our aim is to investigate any association between peripheral vascular rheology and distribution of coronary artery disease (CAD) in middle aged erectile dysfunction (ED) population.
Methods:...
Conference Abstract
P.096 ROLE OF ARGINASE PATHWAY IN RESPONSE TO SHEAR STRESS: NEW POTENTIAL THERAPEUTIC TARGETS FOR ATHEROSCLEROSIS?
R.F. da Silva, V. Gambillara, C. Cheng, D. Segers, R. de Crom, R. Krams, N. Stergiopulos
Pages: 74 - 75
Conference Abstract
P78 LONGITUDINAL MICRO-ULTRASOUND ASSESSMENT OF THE OB/OB MOUSE MODEL: EVALUATION OF CARDIOVASCULAR, RENAL AND HEPATIC PARAMETERS
Nicole Di Lascio, Claudia Kusmic, Francesco Stea, Francesca Lenzarini, Cristina Barsanti, Arthur Leloup, Francesco Faita
Pages: 74 - 75
Purpose/Background/Objectives: Obesity is associated with increased risk factors for cardiovascular disease (CVD). Leptin-deficient mice (ob/ob) are widely employed to investigate obesity. This study is aimed at providing a micro-ultrasound (mUS) longitudinal evaluation of the ob/ob mouse in terms of...
Conference Abstract
11.3 ATHEROMATOSIS AND ENDOTHELIAL RESPONSE OF THE SMALL PERIPHERAL ARTERIES: A PERITONEAL DIALYSIS VERSUS HEMODIALYSIS PATIENTS MISMATCH
Athanasios Angelis, Nikolaos Ioakimidis, Penny Giannou, Ioannis Felekos, Vasiliki Kakiouzi, Konstantina Aggeli, Dimitrios Petras, Charalampos Vlachopoulos, Dimitrios Tousoulis
Pages: 74 - 74
Background: Peritoneal dialysis (PD) and hemodialysis (HD) are treatment options for end stage renal disease (ESRD). However, few are known on the cardiovascular impose of those therapeutic modalities. Our aim is to uncover endothelial damage and subclinical atheromatous process in male patients on chronic...
Short Communication
Agreement between carotid and radial augmentation index: Does medication status affect the relation?☆
Jun Sugawara, Hidehiko Komine, Koichiro Hayashi, Mutsuko Yoshizawa, Takashi Yokoi, Seiji Maeda, Hirofumi Tanaka
Pages: 74 - 76
Central augmentation index (AI) is an index for arterial stiffness and wave reflection, but the measurement requires technical precision. We recently reported that AI obtained directly from radial arterial pressure waveforms (without using the general transfer function) could provide equivalent information...
Conference Abstract
P.097 ADRENALECTOMY IS MORE EFFECTIVE THAN SPIRONOLACTONE IN REDUCING ARTERIAL STIFFNESS IN PRIMARY ALDOSTERONISM☆
B. Strauch, O. Petrak, D. Wichterle, T. Zelinka, R. Holaj, J. Dvorakova, L. Safarik, M. Kasalicky, J. Widimsky
Pages: 75 - 75
Conference Abstract
3.8 CHILDHOOD OBESITY: DOES IT HAVE ANY EFFECT ON YOUNG ARTERIES?
Erzsébet Valéria Hidvégi, Andrea Emese Jakab, Miklós Illyés, Attila Cziráki
Pages: 75 - 75
Background: Prevalence of overweight (OW) and obesity (O) in children and adolescents has been increased in the past three decades. Obese children are prone to develop early cardiovascular (CV) morbidity in their adult life. Impaired arterial stiffness might be detected in this population. The aim of...
Conference Abstract
P79 ULTRASONOGRAPHIC CHARACTERIZATION OF THE DB/DB MOUSE, AN ANIMAL MODEL OF METABOLIC ABNORMALITIES
Nicole Di Lascio, Chiara Rossi, Claudia Kusmic, Anna Solini, Francesco Faita
Pages: 75 - 75
Purpose/Background/Objectives: The availability of an animal model that, beside common blood parameters like hyperglycemia or high lipid levels, reliably mirrors organ damage occurring in metabolic diseases, is an urgent need. These animals have not been fully characterized in terms of cardiovascular,...
Conference Abstract
11.4 RELATIONSHIP BETWEEN INFLAMMATORY CYTOKINES AND AORTIC STIFFNESS IN PATIENTS WITH CHRONIC KIDNEY DISEASE
Marie-Pier Desjardins, Aboubacar Sidibe, Catherine Fortier, Sacha De Serres, Richard Larivière, Mohsen Agharazii
Pages: 75 - 75
Introduction: Cardiovascular diseases are the primary cause of morbidity and mortality in patients with chronic kidney disease (CKD). Aortic stiffness is a non-traditional risk factor in these patients. Using an animal model of CKD with vascular calcification, we reported that inflammation is involved...
Conference Abstract
P.098 INCREASED ARTERIAL STIFFNESS AND ARTERIAL WAVE REFLECTIONS ARE ASSOCIATED WITH IMPAIRED FUNCTIONAL STATUS IN PATIENTS WITH NORMAL EJECTION FRACTION
T. Weber, J. Auer, M. O’Rourke, B. Eber
Pages: 75 - 75
Conference Abstract
4.1 PROBING ARTERIAL STIFFNESS AT THE NANO-SCALE USING THE INTERNAL MAMMARY ARTERY AS A NOVEL TARGET
Riaz Akhtar, Zhuo Chang, Maria Lyck Hansen, Hans Christian Beck, Lars Melholt Rasmussen
Pages: 75 - 75
Introduction: Arterial stiffening is associated with structural and biomechanical alterations in the aorta. However, there are still gaps in our understanding as to how the structure and properties of arteries across the vasculature are altered with high PWV.Objective: To determine whether altered ultrastructural...
Conference Abstract
P80 IDENTIFICATION OF RADIAL VASCULAR WALL ABNORMALITIES BY VERY-HIGH FREQUENCY ULTRASOUND IN PATIENTS WITH FIBROMUSCULAR DYSPLASIA: THE FUCHSIA STUDY
Rosa Maria Bruno, Nicole Di Lascio, Daniela Guarino, Saverio Vitali, Piercarlo Rossi, Davide Caramella, Stephane Laurent, Pierre Boutouryie, Stefano Taddei, Lorenzo Ghiadoni, Francesco Faita
Pages: 75 - 75
Aim: This case-control study is aimed at identifying radial vascular wall abnormalities in patients with fibromuscular dysplasia (FMD).
Methods: High-frequency ultrasound scans of radial arteries were obtained by VevoMD (70 MHz probe, FUJIFILM, VisualSonics). Radial wall showed two echogenic interfaces:...
Conference Abstract
11.5 DIFFERENCES OF HEART RATE VARIABILITY AND AUGMENTATION INDEX BETWEEN DIALYSIS AND POST-DIALYSIS PERIODS IN PATIENTS WITH END-STAGE RENAL DISEASE
Stefan Hagmair, Matthias Christoph Braunisch, Martin Bachler, Anna-Lena Hasenau, Axel Bauer, Konstantinos Rizas, Siegfried Wassertheurer, Marcus Baumann, Christopher Mayer, Christoph Schmaderer
Pages: 75 - 75
Introduction: Heart rate variability (HRV) analysis is a non-invasive tool for assessing the cardiac health. There is evidence that the cardiac autonomic system and central hemodynamics respond to hemodialysis. The aim of this work is to compare HRV parameters and augmentation index (AIx) between intra-...
Conference Abstract
P.099 PREDICTIVE VALUE OF AORTIC PULSE WAVE VELOCITY IN ASYMPTOMATIC PATIENTS FOR CAROTID ATHEROSCLEROSIS
B. Benczur, R. Bocskei, M. Illyes
Pages: 75 - 75
Conference Abstract
4.2 DISCREPANCY BETWEEN IN-VIVO MEASURE AND EX-VIVO CALCULATION OF PULSE WAVE VELOCITY IN RETINAL ARTERIES
Mahdieh Rezaeian, Arthur Leloup, Angela Schulz, Mojtaba Golzan, Stuart Graham, Alberto P. Avolio, Mark Butlin
Pages: 75 - 75
Background: Pulse wave velocity (PWV) in large arteries is a pressure-dependent marker of arterial stiffness. The retinal vasculature provides unique access to the microcirculation. There is inconsistency between reported values of retinal PWV (rPWV). The pressure dependency of rPWV was measured in-vivo...
Conference Abstract
P81 DISARRAY AND REMODELING OF THE RADIAL ARTERY IN WOMEN WITH SPONTANEOUS CORONARY ARTERY DISSECTION: THE FUCHSIA STUDY
Rosa Maria Bruno, Nicole Di Lascio, Abtehale Al Hussaini, Daniela Guarino, Saverio Vitali, Piercarlo Rossi, Davide Caramella, Bernardo Cortese, Francesco Faita, Stefano Taddei, Lorenzo Ghiadoni, David Adlam
Pages: 75 - 76
Background: Spontaneous coronary dissection (SCAD) may represent a manifestation of fibromuscular dysplasia (FMD); thus, preclinical lesions might be found in extracoronary vessels with similar size and wall ultrastructure, such as the radial artery.
Methods: Two 5′-clips from the left radial artery...
Conference Abstract
11.6 THE AORTIC-TO-BRACHIAL STIFFNESS GRADIENT AND AORTIC RESERVOIR-EXCESS PRESSURE IN A DIALYSIS POPULATION
Catherine Fortier, Marie-Pier Desjardins, Aboubacar Sidibe, Mathieu Allard, Martin G. Schultz, James E. Sharman, Mohsen Agharazii
Pages: 75 - 75
Background: Aortic reservoir function is associated with increased cardiovascular events. Patients with chronic kidney disease in need of dialysis have increased aortic stiffness and reversal of the aortic-to-brachial stiffness gradient, which could impair aortic reservoir function. The aim of this study...
Conference Abstract
P.100 INVASIVE VALIDATIONS OF A USER INDEPENDENT OSCILLOMETRIC DEVICE (ARTERIOGRAPH) FOR MEASURING AUGMENTATION INDEX AND AORTIC PULSE WAVE VELOCITY
I. Horvath, L. Papp, L. Papp, M. Illyes
Pages: 75 - 76
Conference Abstract
4.3 WHOLE-BODY VS. REGIONAL ARTERIAL STIFFNESS: IMPLICATIONS FOR A SINGLE WINDKESSEL MODEL OF THE CIRCULATION
Joseph Izzo, Sherif El-sayed, Rahil Ahmed, Peter Osmond, Benjamin Gavish
Pages: 75 - 76
Introduction: We questioned whether a single Windkessel (WK) adequately describes the circulation by estimating the radial arterial diastolic pressure-decay constant (tau) and combining this with systemic hemodynamic and arterial stiffness measurements.
Methods: In the non-invasive cardiac laboratory,...
Review Article
Towards a consensus on the understanding and analysis of the pulse waveform: Results from the 2016 Workshop on Arterial Hemodynamics: Past, present and future
Patrick Segers, Michael F. O’Rourke, Kim Parker, Nico Westerhof, Alun Hughes, on behalf of the Participants of the 2016 Workshop on Arterial Hemodynamics: Past, present and future
Pages: 75 - 80
This paper aims to summarize and map contemporary views on some contentious aspects of arterial hemodynamics that have remained unresolved despite years of research. These were discussed during a workshop entitled Arterial hemodynamics: past, present and future held in London on June 14 and 15, 2016....
Research Article
A novel measure to characterise optimality of diameter relationships at retinal vascular bifurcations
Nicholas W. Witt, Neil Chapman, Simon A. McG. Thom, Alice V. Stanton, Kim H. Parker, Alun D. Hughes
Pages: 75 - 80
Conventionally, the relationship between parent and daughter vessels at vascular bifurcations has been expressed by the junction exponent (x), and deviations of this parameter from the optimal conditions predicted by Murray’s law (x = 3) have been shown to be associated with vascular disease. However,...
Research Article
Homebased Standing Core Exercise Training Improves Femoral Blood Flow but not Arterial Stiffness in Middle-Aged to Older Adults
Hsin-Fu Lin, Soun-Cheng Wang, Hao-Min Cheng, Jun Sugawara
Pages: 75 - 81
Homebased exercise is often advocated to improve physical fitness in the aging population, especially when outdoor activity is not available. Yet we often have a limited understanding of its training effects for clinical uses.
Aim: To investigate a short-term exercise training of standing core exercise...
Conference Abstract
4.4 CAN LASER DOPPLER VIBROMETER DETECT CAROTID STENOSIS FROM SKIN VIBRATIONS? HYDRAULIC BENCH TESTS ON PATIENT-SPECIFIC MODEL
Viviana Mancini, Daniela Tommasin, Yanlu Li, Roel Baets, Stephen Greenwald, Patrick Segers
Pages: 76 - 76
Background: Within the H2020 CARDIS project, we explore the use of a Laser Doppler Vibrometer (LDV) [1] to detect asymptomatic carotid stenosis from measurement of skin vibrations on the neck of affected patients. We hypothesise that flow instabilities induced by the stenosis will propagate as mechanical...
Conference Abstract
P82 IMAGE-BASED CHARACTERIZATION OF PLAQUE LIPID CONCENTRATION CHANGES IN TIME AND THE ROLE OF STATIN THERAPY
Kristen Meiburger, Gianfranco Varetto, Pietro Rispoli, Filippo Molinari
Pages: 76 - 76
Introduction: Carotid artery atherosclerosis is an established risk factor for cerebrovascular events. Core lipid-rich plaques are considered at a higher risk of embolization compared to fibrous or calcified lesions. Contrast enhanced ultrasound (CEUS) is effective for studying carotid plaques, providing...
Conference Abstract
11.7 AORTIC CALCIUM SCORE AFFECTS NON-INVASIVELY OBTAINED ESTIMATES OF CENTRAL BLOOD PRESSURE IN PATIENTS WITH ADVANCED CHRONIC KIDNEY DISEASE
Rasmus K. Carlsen, Christian D. Peters, Esben Laugesen, Simon Winther, Dinah S. Khatir, Hans E. Boetker, Morten Boettcher, Per Ivarsen, My Svensson, Niels H. Buus
Pages: 76 - 76
Background: We recently reported that central blood pressure (BP) obtained non-invasively in chronic kidney disease (CKD) patients significantly underestimated the central BP with decreasing eGFR in comparison with invasively measured true central BP in the aorta. This post-hoc analysis investigated...
Conference Abstract
4.5 CARDIAC OUTPUT ESTIMATION FROM BEAT-TO-BEAT RADIAL PRESSURE AND PULSE WAVE VELOCITY: A MODEL-BASED STUDY
Vasiliki Bikia, Stamatia Pagoulatou, Theodore G. Papaioannou, Nikolaos Stergiopulos
Pages: 76 - 76
Background: Cardiac output (CO) monitoring remains a salient challenge. The state-of-the-art is based on generalized transfer functions and parameter estimations from pooled clinical data, which do not necessarily reflect the state of the cardiovascular system in a patient-specific way. Here, we introduce...
Conference Abstract
P83 A PILOT STUDY TO ASSESS PEAK SYSTOLIC VELOCITY AS A POSSIBLE MARKER OF ATHEROSCLEROTIC BURDEN USING ULTRASOUND
Carola Koenig, Mark Atherton, Marco Cavazzuti, Sudarshan Ramachandran, Corinna Gomm, Richard Strange, Ian Halliday, Torsten Schenkel
Pages: 76 - 76
Introduction: Ischemic heart disease (IHD) has been associated with lower peak systolic velocity (PSV) on penile Doppler measurements [1]. This study establishes whether carotid ultrasound (US) PSV was associated with computational fluid dynamics (CFD) outputs, which in turn may contribute to IHD pathogenesis.
Methods:...
Conference Abstract
11.8 AORTIC SYSTOLIC BLOOD PRESSURE IS NO LONGER MARKER OF THE ARTERIAL STIFFNESS IN STABLE PATIENTS WITH HEART FAILURE WITH REDUCED EJECTION FRACTION
Evgeny Tyukhmenev, Svetlana Villevalde, Zhanna Kobalava
Pages: 76 - 76
The aim of the study was to assess arterial stiffness and its diagnostic and prognostic value in patients with arterial hypertension (AH) and heart failure with reduced ejection fraction (HFrEF).
Methods: In 93 stable patients (75% male, age 64±9 years (MSD), history of myocardial infarction 67%, diabetes...
Conference Abstract
P84 HIGH-FRAME RATE VECTOR FLOW IMAGING: RELATIONSHIP BETWEEN CAROTID BIFURCATION GEOMETRY AND FLOW PATTERNS
A. Alfredo Goddi, L. Luca Aiani, Y. Yigang Du, X. Xujin He, Y. Yingying Shen, L. Lei Zhu
Pages: 76 - 77
Background: The laminar flow movement in straight arteries is affected by anatomical factors such as bifurcation, lumen diameter changes or plaques. As a consequence of the local deceleration, the detachment of the boundary layer from the wall develops a disturbed flow, which impacts hemodynamics. It...
Conference Abstract
11.9 PARAMETERS OF ARTERIAL STIFFNESS HAVE INDEPENDENT PROGNOSTIC VALUE IN STABLE PATIENTS WITH HEART FAILURE WITH REDUCED EJECTION FRACTION
Evgeny Tyukhmenev, Svetlana Villevalde, Zhanna Kobalava
Pages: 76 - 76
The purpose of the study was to determine the prognostic value of ventricular-arterial coupling (VAC) in patients with arterial hypertension (AH) and stable heart failure with reduced ejection fraction (HFrEF).
Methods: In prospective study (follow-up 12–24 months, median 18 months) prognosis of 93...
Conference Abstract
11.10 ARTERIAL ELASTANCE IS ASSOCIATED WITH CENTRAL BLOOD PRESSURE AND ARTERIAL PERIPHERAL RESISTANCE IN PATIENTS WITH HEART FAILURE WITH REDUCED EJECTION FRACTION
Evgeny Tyukhmenev, Svetlana Villevalde, Zhanna Kobalava
Pages: 76 - 76
Objective of the study was to assess ventricular-arterial coupling (VAC), parameters of left ventricular (LV) work efficiency and their determinants in patients with arterial hypertension (HTN) and stable heart failure with reduced ejection fraction (HFrEF).
Methods: In 93 stable patients with HTN and...
Conference Abstract
P.101PULSATILE ARTERIAL PRESSURE IS PREDOMINANTLY DETERMINED BY THE CENTRAL RESERVOIR, WHICH CAN BE DETERMINED NON-INVASIVELY FROM PERIPHERAL MEASUREMENT SITES
J.E. Davies, A. Malaweera, N. Hadjiloizou, K.H. Parker, J. Aguado-Sierra, J. Mayet, D.P. Francis, A.D. Hughes
Pages: 76 - 76
Research Article
Role of Adipose Tissue and Skeletal Muscle in Atherosclerosis and in Central Hemodynamics
Joana Ferreira, Pedro Cunha, Armando Mansilha, Cristina Cunha, Cristina Silva, Isabel Vila, Alexandre Carneiro, Amílcar Mesquita, Jorge Cotter
Pages: 76 - 83
Background: Carotid Arterial Disease (CAD) and peripheral arterial disease (PAD) are atherosclerotic diseases. Adipose tissue (AT) and skeletal muscle (SM) are endocrine organs producing polypeptides with vascular effects. The main objective of this study is to characterize the AT and SM in PAD and CAD....
Conference Abstract
4.6 INFLAMMATION AND AORTIC STIFFNESS. A MULTICENTRE LONGITUDINAL STUDY IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE
Luca Zanoli, Kadir Ozturk, Maria Cappello
Pages: 77 - 77
Background: Inflammatory Bowel Disease (IBD) is characterized by a low prevalence of traditional risk factors, an increased aortic pulse-wave velocity (aPWV) [1] and an excess of cardiovascular events. We have previously hypothesized that the difference between expected and observed cardiovascular risk...
Conference Abstract
P85 HIGH FRAME RATE DYNAMIC DISPLAY ULTRASOUND VECTOR FLOW IMAGING FOR QUANTITATIVE STUDIES OF HEMODYNAMICS OF CAROTID ARTERIES
Yigang Du, Xujin He, Yingying Shen, Lei Zhu, Alfredo Goddi
Pages: 77 - 77
Advanced atherosclerotic patients are faced with significant risks of stroke, which are very likely to cause death or irreversible physical disability. However, the growth of artery stenosis usually needs a very long development. Early diagnosis is necessary and requires detailed and accurate quantitative...
Conference Abstract
12.1 EVALUATION OF ACUTE EFFECTS OF COFFEE CONSUMPTION ON ARTERIAL STIFFNESS IN HEALTHY ADULT PEOPLE USING AN OSCILLOMETRIC DEVICE
Pedro Forcada, Dario Echeverry, Alejandro Pizano, Felix Montes, Daniel Acuña
Pages: 77 - 77
Environment/Objectives: Several studies in different populations and conditions shown contradictory results about the effect of coffee on arterial stiffness (AS). Coffee consumption is high around the world and it is very important to define its CV effects.
To evaluate the acute effects on haemodynamic...
Conference Abstract
4.7 THE EFFECT OF TRANSCATHETER AORTIC VALVE IMPLANTATION ON AORTIC STIFFNESS AND HEMODYNAMICS
Vasiliki Gardikioti, D. Terentes-Printzios, C. Vlachopoulos, K. Toutouzas, M. Xanthopoulou, G. Benetos, G. Latsios, V. Penesopoulou, V. Tsigkou, G. Siasos, E. Vavuranakis, D. Tousoulis
Pages: 77 - 77
Purpose/Background/Objectives: Aortic stiffness and central hemodynamics are established vascular biomarkers. Transcatheter aortic valve implantation (TAVI) is a promising new technique for the treatment of aortic valve stenosis in elderly patients. We examined the effect of TAVI on the elastic properties...
Conference Abstract
P120 A MODEL-BASED STUDY ON THE EVOLUTION OF BLOOD PRESSURE DURING AGEING
Stamatia Pagoulatou, Nikolaos Stergiopulos
Pages: 77 - 78
Background: Hypertension being a major risk factor of cardiovascular mortality, there is a pressing need to understand the ageing mechanisms that lead to the continuous increase of pulse pressure and systolic blood pressure over time. Alterations in both forward and backward waves with age have been...
Conference Abstract
12.2 HIGH PULSE WAVE VELOCITY IS ASSOCIATED WITH INCREASED VISIT-TO-VISIT SYSTOLIC BLOOD PRESSURE VARIABILITY IN CONTROLLED ARTERIAL HYPERTENSION
Elena Troitskaya, Yulia Kotovskaya, Zhanna Kobalava
Pages: 77 - 77
Background: Visit-to-visit blood pressure variability (BPV) is associated with adverse cardiovascular outcomes in different patients’ populations1–2. Arterial stiffness is a potential mechanism of increased visit-to-visit BPV3. Carotid–femoral PWV has become increasingly important for total cardiovascular...
Conference Abstract
4.8 PLACENTAL NA/K-ATPASE INHIBITOR MARINOBUFAGENIN INDUCES ARTERIAL WALL FIBROSIS IN PREECLAMPSIA
Olga Fedorova, Natalia Aglakova, Yulia Grigorova, Vitalily Reznik, Valintina Zernetkina, Wen Wei, Edward Lakatta, Alexei Bagrov
Pages: 77 - 78
Background: Previous studies implicated cardiotonic steroids, including Na/K-ATPase inhibitor marinobufagenin (MBG), in the pathogenesis of preeclampsia (PE). Immunoneutralization of heightened MBG by Digibind, a digoxin antibody, reduces blood pressure (BP) in patients with PE, and anti-MBG monoclonal...
Conference Abstract
12.3 24 HOUR AMBULATORY BLOOD PRESSURE MONITORING AND PULSE WAVE VELOCITY PATTERNS IN KENYAN ADOLESCENTS
Anthony Etyang
Pages: 77 - 77
Background: There are no data on ambulatory blood pressure monitoring (ABPM) and arterial stiffness parameters in sub-Saharan African children. We performed 24-hour ABPM and pulse wave velocity (PWV) measurements in adolescents living in 2 slums in Nairobi, Kenya.
Methods: We selected 1,100 11–17 year...
Conference Abstract
12.5 IMPAIRED REGULATION OF ARTERIAL WALL VISCOSITY DURING CHANGES IN BLOOD FLOW IN ESSENTIAL HYPERTENSIVE PATIENTS
Frederic Roca, Michele Iacob, Guillaume Feugray, Christian Thuillez, Jeremy Bellien, Robinson Joannides
Pages: 77 - 78
Background: Arterial wall viscosity (AWV) is a major source of cardiac energy dissipation along the arterial tree. Evolution of AWV during increase in blood flow and the impact of essential hypertension on this evolution have never been studied.
Methods: Radial artery diameter, wall thickness and arterial...
Case Report
Little Old Ladies’ Eye
Martin Middeke, Joachim Nasemann, Friedrich Cameron Luft
Pages: 77 - 80
Conference Abstract
PERINDOPRIL/INDAPAMIDE FIXED COMBINATION AND REGRESSION OF TARGET ORGAN DAMAGE: ACTING THROUGH MACRO AND MICROCIRCULATION
Bernard I. Lévy
Pages: 77 - 77