Artery Research

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Volume 24, Issue C, December 2018, Pages 75 - 75

3.8 CHILDHOOD OBESITY: DOES IT HAVE ANY EFFECT ON YOUNG ARTERIES?

Authors
Erzsébet Valéria Hidvégi1, Andrea Emese Jakab2, Miklós Illyés3, Attila Cziráki3
1Dr. Jakab & Co. Ltd, Pediatric Cardiology, Szolnok, Hungary
2Dept. of Pediatrics, Albert Szent-Györgyi University, Szeged, Hungary
3Heart Institute, Faculty of Medicine, University of Pécs, Pécs, Hungary
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.039How to use a DOI?
Abstract

Background: Prevalence of overweight (OW) and obesity (O) in children and adolescents has been increased in the past three decades. Obese children are prone to develop early cardiovascular (CV) morbidity in their adult life. Impaired arterial stiffness might be detected in this population. The aim of our study was to compare the arterial function parameters (AFPs) in O/OW patients and healthy subjects.

Methods: 6.816 subjects (3.668 boys) aged 3–18 years were recruited and categorised by their body mass index (BMI) into normal weight (N), OW and O groups regarding their age and sex. AFPs were measured by occlusive-oscillometric device. Propensity score matching was carried as statistical test.

Results: 19.9% (n = 1.356) of the population were OW/O, 911 (516 boys) were OW and 445 (273 boys) were O. PWVao did not differ significantly between N (5.9 ± 0.8 m/s) and OW patients (5.9 ± 0.8 m/s); and N (6.0 ± 0.7 m/s) and O patients (6.0 ± 0.8 m/s). Aixao was significantly lower in OW (9.3 ± 7.4% vs 7.6 ± 7.0%, p < 0.00001) and in O patients (9.7 ± 8.1% vs 6.6 ± 7.2%, p < 0.00001) compared to controls. No significant difference was found regarding SBPao values between controls and OW and O groups (N = 110.7 ± 12.4 mmHg vs OW = 110.3 ± 11.9 mmHg; N = 115.6 ± 14.0 mmHg vs O = 114.3 ± 12.8 mmHg).

Conclusions: Aortic stiffness – expressed by PWVao – did not differ between N and O/OW children and adolescents, however Aixao was remarkably, significantly lower in O/OW patients. We may conclude that the pathophysiological consequences in the circulatory system due to childhood OW/O are compensated hemodynamically in these patients, presumably by decreasing total peripheral vascular resistance.

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<Previous Article In Issue
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Journal
Artery Research
Volume-Issue
24 - C
Pages
75 - 75
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.039How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Erzsébet Valéria Hidvégi
AU  - Andrea Emese Jakab
AU  - Miklós Illyés
AU  - Attila Cziráki
PY  - 2018
DA  - 2018/12/04
TI  - 3.8 CHILDHOOD OBESITY: DOES IT HAVE ANY EFFECT ON YOUNG ARTERIES?
JO  - Artery Research
SP  - 75
EP  - 75
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.039
DO  - 10.1016/j.artres.2018.10.039
ID  - Hidvégi2018
ER  -