Artery Research

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Volume 16, Issue C, December 2016, Pages 72 - 73

10.7 NON-INVASIVE ESTIMATION OF CENTRAL SYSTOLIC PRESSURE: A COMPARISON BETWEEN RADIAL ARTERY TONOMETRY AND A NEW DIRECT CENTRAL BLOOD PRESSURE ESTIMATION METHOD (DCBP)

Authors
Denis Chemla2, Sandrine Millasseau3, Edmund Lau4, Nathalie Richard3, Pierre Attal1, Mabrouk Brahimi1, Alain Nitenberg1
1Paris South University-Inserm U999, Paris, France
2Assistance Publique Hopitaux de Paris, France
3Alam Medical, Vincennes, France
4University of Sydney, Australia
Available Online 24 November 2016.
DOI
10.1016/j.artres.2016.10.085How to use a DOI?
Abstract

Background: We have developed a new proprietary method (DCBP® Direct Central Blood Pressure) to estimate central systolic blood pressure (cSBP) directly from peripheral pressure. In a previous meta-analysis of published high-fidelity pressure studies with simultaneous aortic and brachial pressure recordings, negligible mean difference between DCBP and cSBP has been documented (1). The accuracy and precision of DCBP against arterial tonometry measurements remain to be documented.

Methods: The cSBP was estimated from radial artery tonometry and a transfer function using a SphygmoCor® system (AtCor Medical, Australia) in 100 subjects (mean age+/-SD = 57+/-10 years). Pressure waveforms were calibrated from the brachial systolic and diastolic pressures, measured just prior to tonometric measurement with an oscillometric cuff system (Omron 705CP Omron, Japan). DCBP and cSBP were compared using the Bland and Altman method and subgroups were compared using unpaired Student’s t test.

Results: The difference between DCBP (129.2+/−16.8 mmHg) and cSBP (129.4+/−16.4 mmHg) was −0.2+/−2.6 mmHg. The difference was not influenced by the mean (DCBP + cSBP / 2). Similar results were obtained in men (n=60) and women (n=40), and in subjects with/without hypertension (n=51/49), with/without diabetes (26/74), and with/without dyslipidemia (36/64).

Conclusions: The new DCBP® method and the transfer function applied to radial tonometry method were interchangeable in estimating central SBP. These results pertained strictly to the studied population (patients aged 57 years on average, and displaying a high percentage of cardiovascular risk factors). Further studies are needed to confirm our results.

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This is an open access article distributed under the CC BY-NC license.

References

1.D Chemla, S Millasseau, EMT Lau, P Attal, and A Nitenberg, Direct estimation of central systolic pressure from peripheral pressures: a proof of concept based on the meta-analysis of high-fidelity pressure studies, ESH 2016 – 26th European Meeting on Hypertension and Cardiovascular Protection, Paris, France, 12 June 2016.
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Journal
Artery Research
Volume-Issue
16 - C
Pages
72 - 73
Publication Date
2016/11/24
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2016.10.085How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Denis Chemla
AU  - Sandrine Millasseau
AU  - Edmund Lau
AU  - Nathalie Richard
AU  - Pierre Attal
AU  - Mabrouk Brahimi
AU  - Alain Nitenberg
PY  - 2016
DA  - 2016/11/24
TI  - 10.7 NON-INVASIVE ESTIMATION OF CENTRAL SYSTOLIC PRESSURE: A COMPARISON BETWEEN RADIAL ARTERY TONOMETRY AND A NEW DIRECT CENTRAL BLOOD PRESSURE ESTIMATION METHOD (DCBP)
JO  - Artery Research
SP  - 72
EP  - 73
VL  - 16
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2016.10.085
DO  - 10.1016/j.artres.2016.10.085
ID  - Chemla2016
ER  -