Artery Research
2994 articles
Research Article
P.078 REFERENCE VALUES IN WHITE EUROPEANS FOR THE ARTERIAL PULSE WAVE RECORDED BY MEANS OF THE SPHYGMOCOR DEVICE
W. Wojciechowska*, J.A. Staessen, T. Nawrot, M. Cwynar, J. Kucerová, K. Stolarz, J. Gasowski, M. Tichá, L. Thijs, T. Grodzicki, K. Kawecka-Jaszcz, J. Filipovský
Pages: S45 - S45
Conference Abstract
P3 Factor Influencing Endothelial Function in Type 2 Diabetes Mellitus with Newly Diagnosed Hypertension
Prachi Srivastava
Pages: S45 - S45
Background: Increased risk for cardiovascular diseases is associated with diabetes, can be partially attributed to endothelial dysfunction. However, the cumulative factors leading to endothelial dysfunction in Type 2 DM are not clear. In the current study, a novel attempt was made to understand factors...
Conference Abstract
P.23 Relationship Between Aortic Stiffness, Aortic, and Carotid Impedance with Vascular Aging in Community-Based Healthy People
Chao-Feng Liao, Shao-Yuan Chuang, Hao-Min Cheng, Chen-Huan Chen
Pages: S45 - S46
Background: Stiffening of the aorta has been associated with microvascular structural brain damage and cognitive dysfunction in cross-sectional and longitudinal studies, probably due to the reduced wave reflection at the interface between carotid and aorta and transmission of excessive flow pulsatility...
Conference Abstract
P.075 PREDICTORS OF LARGE ARTERIAL STIFFENING AND WAVE REFLECTIONS IN DIABETES: THE EFFECTS OF AUTONOMIC NEUROPATHY AND ERECTILE DYSFUNCTION
S. Bunce, A. Stride, C. Matthews, J.C. Smith*
Pages: S45 - S45
Conference Abstract
P.077 ARTERIAL WALL REMODELING USING A CONSTITUENT-BASED MODEL
N. Stergiopulos*, M. Zulliger, S. Roy, E. Fonck, R. Rezakhaniha, A. Tsamis
Pages: S45 - S45
Research Article
P.080 GRADED ASSOCIATION BETWEEN ARTERIAL STIFFNESS AND DIVERSE INFLAMMATORY MARKERS IN NEWLY DIAGNOSED ESSENTIAL HYPERTENSIVE SUBJECTS: LINKING PROINFLAMMATORY MECHANISMS WITH VASCULAR DYSFUNCTION
K. Dimitriadis*, C. Tsioufis, C. Vasiliadou, K. Giannakopoulos, A. Kakkavas, I. Skiadas, C. Stefanadis, I. Kallikazaros
Pages: S46 - S46
Research Article
P.079 PULSE WAVE VELOCITY IN SUBJECTS WITH MASKED HYPERTENSION AND WHITE COAT HYPERTENSION
K. Stolarz*, W. Wojciechowska, A. Olszanecka, W. Lubaszewski, M. Cwynar, T. Grodzicki, K. Kawecka-Jaszcz
Pages: S46 - S46
Conference Abstract
P4 Aldosterone-Induced Vascular Dysfunction by Decreasing Nuclear Factor Erythroid 2–Related Factor 2 Activity and Increasing Reactive Oxygen Species Generation
Daniel Rodrigues, Tiago Januário da Costa, Rafael Menezes da Costa, Rita de Cássia Aleixo Tostes Passaglia
Pages: S46 - S46
Introduction: Chronic increases in aldosterone (Aldo) levels (hyperaldosteronism) increases blood pressure and induces hypertension. In the cardiovascular system, Aldo stimulates reactive oxygen species (ROS) generation. ROS contribute to vascular dysfunction by increasing vascular smooth muscle contractile...
Conference Abstract
P.081 HYPERTENSIVE SUBJECTS WITH AN EXAGGERATED BLOOD PRESSURE EXERCISE RESPONSE ARE CHARACTERIZED BY A STATE OF INFLAMMATORY ACTIVATION, IMPAIRED THROMBOSIS/FIBRINOLYSIS SYSTEM AND ARTERIAL STIFFENING
C. Tsioufis*, K. Dimitriadis, D. Tsiachris, P. Pavlidis, K. Thomopoupoulos, A. Michailidis, C. Stefanadis, I. Kallikazaros
Pages: S46 - S46
Conference Abstract
P.082 DIFFERENTIAL ASSOCIATIONS OF LEFT ATRIUM VOLUME WITH BNP AND AORTIC STIFFNESS IN THE EARLY STAGES OF ESSENTIAL HYPERTENSION: IMPORTANCE OF MECHANICAL AND HUMORAL COMPONENTS
C. Katsaris*, C. Tsioufis, E. Taxiarchou, P. Stougiannos, M. Selima, E. Vezali, C. Stefanadis, I. Kallikazaros
Pages: S46 - S46
Research Article
P.085 ACUTE EFFECT OF VOLUME EXCHANGE ON CENTRAL HEMODYNAMICS IN PERITONEAL DIALYSIS
F. Verbeke*, W. Van Biesen, A. Pletinck, L.M. Van Bortel, R. Vanholder
Pages: S47 - S47
Research Article
P.087 PULSE PRESSURE, AUGMENTATION INDEX AND PULSE WAVE VELOCITY IN SEVERE CARDIOMYOPATHY – IMPLICATIONS FOR RISK STRATIFICATION
T. Weber*, J. Auer, M.F. O’Rourke, B. Eber
Pages: S47 - S48
Research Article
P.086 EVALUATION OF ARTERIAL DISTENSIBILITY IN HYPERTENSIVE PATIENTS TREATED WITH IRBESARTAN
A. Vicente Casanova*, J. Redón i Más, J. Aznar Vicente
Pages: S47 - S47
Conference Abstract
P5 Aortic Volume Wave Velocity (VWV) in Chronic Heart Failure (CHF) Measured During the 12 Channel Routine ECG by Impedance Plethysmography Relates Negatively to Appendicular Muscle Mass (AppMM)
Falko Skrabal, Johannes Boyer, Hasib Ehsas, Katharina Skrabal
Pages: S47 - S47
Introduction: Pulse wave velocity or (or VWV) may relate to muscle mass and body fat. We have included measurements for the above in the routine 12 channel ECG.
Methods: A 12 channel ECG supplies impedance plethysmographic measurements at the four extremities at 40 kHz [1]. From these VWW was derived...
Conference Abstract
P.24 Factors Associated with Premature Vascular Aging in Patients with Arterial Hypertension
I.V. Inna Melekhina, E.G. Elizaveta Georgievna Medvedeva, S.V. Svetlana Ivanova, E.N. Elena Yushchuk, E.Yu. Ekaterina Trush
Pages: S47 - S47
Objectives: Identification of factors associated with premature vascular aging in patients with arterial hypertension (AH).
Methods: The study included 61 patients (29 men, 32 women) with 1–2 grade AH without cardiovascular complications, aged 40 to 60 years, of which 28 (45.9%) had type 2 diabetes....
Conference Abstract
P.083 THE INCREMENTAL EFFECT OF OBSTRUCTIVE SLEEP APNEA SYNDROME ON ARTERIAL STIFFNESS IN NEWLY DIAGNOSED ESSENTIAL HYPERTENSIVE SUBJECTS
K. Thomopoulos*, C. Tsioufis, A. Amfilochiou, E. Vezali, M. Alchanatis, D. Tousoulis, C. Stefanadis, I. Kallikazaros
Pages: S47 - S47
Conference Abstract
P.084 VARIATIONS OF INTIMA MEDIA THICKNESS DURING CARDIAC CYCLE
H. van Langen*
Pages: S47 - S47
Research Article
P.090 ARTERIAL STIFFNESS AND ITS RELATION TO ENDOTHELIAL AND MICROCIRCULATORY FUNCTIONS IN HEALTHY MALES
C.I. Wright*, H.J. Scholten, J.C.M. Schilder, B.M. Elsen, W. Hanselaar, C.I. Kroner, R. Draijer, J.P.P. Kastelein, W. Stok, J. Karemaker, E. de Groot
Pages: S48 - S48
Research Article
P.089 CAROTID INTIMA-MEDIA THICKNESS IN NON-SMOKING HIV PATIENTS TREATED WITH ANTIRETROVIRAL THERAPY: FOCUS ON LIPID PROFILE
N. Wiinberg*, A.M. Lebech, U.S. Kristoffersen, B. Hesse, J. Gerstoft, C.L. Petersen, A. Kjær
Pages: S48 - S48
Research Article
P.088 INTENSIVE MEDICAL THERAPY NORMALISES FLOW-MEDIATED VASODILATATION AND INTIMA-MEDIA THICKNESS OF PATIENTS WITH COEXISTING HEART FAILURE AND DIABETES
N. Wiinberg*, L. Vestergaard Andersen, C. Tuxen, A. Kjær
Pages: S48 - S48
Research Article
P6 CFD Modelling of Arterialized Venous Flap
Serrano Andreia, Casal Diogo, O’Neill João Goyri, Vassilenko Valentina
Pages: S48 - S48
The knowledge about the required quantity of blood to irrigate an angiosome is important on ischemia (disruption on blood perfusion) prediction, diagnosis and treatment. An angiosome (or flap) is an anatomic unity (or flap) of tissue, it is constituted by skin, subcutaneous tissue and muscle, it is irrigated...
Conference Abstract
P.25 Radial-Digital Pulse Wave Velocity: A Non-Invasive Method for Assessing Stiffness of Peripheral Small Arteries
Hasan Obeid, Charles-Antoine Garneau, Catherine Fortier, Mathilde Pare, Pierre Boutouyrie, Mohsen Agharazii
Pages: S48 - S48
Pulse wave velocity (PWV) has been used to evaluate arterial stiffness of large arteries. Here, we examine the feasibility of radial-digital PWV (RD-PWV) as a measure of stiffness of smaller arteries, and its response to changes in local mean arterial pressure. In 29 healthy subjects, we used Complior...
Conference Abstract
P7 Assessing Vascular Age from Peripheral Pulse Waves: a Study of Existing Indices, and Directions for Future Research
Peter Charlton, Maria Aresu, Jeanette Spear, Phil Chowienczyk, Jordi Alastruey
Pages: S49 - S49
Purpose: Vascular age may be a better marker of cardiovascular risk than age. It has been proposed that vascular age could be assessed easily and inexpensively from the photoplethysmogram (PPG) pulse wave, which is measured by pulse oximeters and fitness bands. Our aim was to assess the performance of...
Conference Abstract
P.26 Liver Transglutaminase 2 Level Comparison Among Different Dietary Interventions
Elif Oztemiz, Soner Dogan, Bilge Guvenc Tuna
Pages: S49 - S49
Purpose/Background/Objectives: Tissue transglutaminase (TG2) is a highly expressed protein especially in endothelial cells. TG2 has several functions including transamidation activity which is important in several processes such as extracellular matrix remodeling [1]. TG2 activity takes place in aortic...
Conference Abstract
P8 O-GlcNAcylation Increases Constriction in Common Carotid Artery of Senescent-Accelerated Female Mice
Tiago J. Costa, Josiane F. Silva, Renée de Nazaré O. da Silva, Paula R. Barros, Juliana Bolsoni, Daniel Rodrigues, Eliana H. Akamine, Rita Tostes
Pages: S50 - S50
The glycosylation with O-linked-N-acetylglucosamine (O-GlcNAc) is an enzymatic process found on nuclear and cytoplasmic proteins. Augmented levels of O-GlcNAc-modified proteins have been associated to cardiovascular disease (CD) in male. However, the association of O-GlcNAc and CD in females it’s not...
Conference Abstract
P.27 Mechanisms of NADPH Oxidase Participation in the Regulation of Diaphragm Artery Contractile Responses
Anna Borzykh, Ilya Kuzmin, Olga Vinogradova, Olga Tarasova
Pages: S50 - S50
Reactive oxygen species (ROS) produced by NADPH-oxidase (NOX) participate in vascular tone control, but their effects in the arteries of respiratory muscles is poorly understood. Possible targets of vasoregulatory ROS influence are NO-pathway in the endothelium and Rho-kinase pathway in smooth muscle...
Conference Abstract
P9 Repeatability and Predictors of a Potentially Blood Pressure-Independent Parameter of Arterial Stiffness
Mark Butlin, James Cox, Bart Spronck, Isabella Tan, Alberto Avolio
Pages: S51 - S51
Background: Arterial stiffness (e.g., as measured by carotid-femoral pulse wave velocity (cfPWV)) changes acutely with blood pressure (BP). High cfPWV at high BP could be due to structural arterial changes or acute BP effects. Various parameters have been proposed as BP-independent parameters of arterial...
Conference Abstract
P.28 Comparison of Regional vs Local Arterial Parameters Using New us Technology
Pedro Forcada, NG Kendy, Ricardo Garcia, Romina Maur, Jose Florio, Horacio Almada
Pages: S51 - S51
Environment: It has been described that muscular arteries behaviour is different from aorta, and regional parameters like IMT, atherosclerotic plaques burden, PWV-c and endothelial function are related with age and risk factors and are powerful prognostic markers but it is not the case of local parameters...
Conference Abstract
P10 Oscillatory Flow Patterns in Peripheral Conduit Artery are Related to Central Arterial Stiffness in Healthy Subjects
Smriti Badhwar, Dinu Chandran, Ashok Jaryal, Rajiv Narang, Chetan Patel, Kishore Kumar Deepak
Pages: S52 - S53
Background: Studies in endothelial cell cultures show that oscillating flow pattern leads to endothelial dysfunction [1]. The only factor known to contribute towards oscillatory flows is peripheral arterial conductance [2]. However, contribution of alterations in central arterial properties to oscillatory...
Conference Abstract
P.29 Involvement of Cannabinoid Receptors in Regulation of MMPs, Cell Proliferation and Apoptosis in Vascular Smooth Muscle Cells
Bettina Greiner, Manuela Sommerfeld, Ulrich Kintscher, Kai Kappert, Elena Kaschina
Pages: S52 - S52
Objectives: Cannabinoid receptors CB1R and CB2R are expressed in the vascular smooth muscle cells (VSMCs) and may contribute to vascular remodeling process (O’Sullivan, 2015). This study aimed to investigate the implication of CB1R and CB2R in the regulation of matrix metalloproteases MMP2 and MMP9,...
Conference Abstract
P.30 Angiotensin II Infusion Leads to Aortic Dissection in LRP8 Deficient Mice
Jeremy Lagrange, Stefanie Finger, Sabine Kossmann, Venkata Garlapati, Wolfram Ruf, Philip Wenzel
Pages: S53 - S53
Background/Objectives: Myeloid cells are crucial for the development of vascular inflammation. Low-density lipoprotein receptor-related protein 8 (LRP8) or Apolipoprotein E receptor 2 (ApoER2), is expressed by macrophages, endothelial cells and platelets and has been implicated in the development of...
Conference Abstract
P11 The Role of Smooth Muscle Integrin Alpha V and TGF-Beta Pathways in Vascular Fibrosis
Alexandre Raoul, Ekaterina Belozertseva, Huguette Louis, Zhenlin Li, Veronique Regnault, Patrick Lacolley
Pages: S54 - S54
It has been demonstrated that arterial stiffness is linked to arterial fibrosis manifested by increased collagen and other extracellular matrix synthesis in smooth muscle cells (SMC). Transmembrane receptors integrins mediating cell-cell and cell-matrix signalling pathways are involved in tissue fibrosis....
Conference Abstract
P.31 Von Willebrand Factor Induces Vascular Smooth Muscle Cell Proliferation and Migration Through Low Density Lipoprotein-Related Receptor Protein 4 and αvβ3 Integrin
Cécile V. Denis, Patrick Lacolley, Jeremy Lagrange, Peter J. Lenting, Jean-Baptiste Michel, Alexandre Raoul, Veronique Regnault
Pages: S54 - S54
Background and Objectives: Von Willebrand factor (VWF) is a plasma glycoprotein involved in primary hemostasis but recent data suggest additional roles beyond hemostasis in angiogenesis and potentially in vascular smooth muscle cell (VSMC) proliferation. Our aim was to investigate how VWF can modulate...
Conference Abstract
P12 Proliferation and Procoagulant Activity of Vascular Smooth Muscle Cells from Thoracic and Abdominal Aortic Aneurysms
Melusine Didelot, Jeremy Lagrange, Jean-Baptiste Michel, Patrick Lacolley, Veronique Regnault
Pages: S55 - S55
In contrast to abdominal aortic aneurysm (AAA), aneurysms of the thoracic ascending aorta (TAA) are not associated with a mural thrombus. Mechanistic understanding of the involvement of vascular smooth muscle cells (VSMCs) in thrombus formation is lacking. We aim to determine (i) whether thrombin generation...
Conference Abstract
P.32 Non-Invasive Measures of Arteriosclerosis Across Childhood and Adolescence: Insights Into the Natural History of Disease
Reeja Nasir, Tommy Ye Cai, Alice Meroni, Michael Skilton
Pages: S55 - S55
Objectives: Non-invasive methodologies for assessing arteriosclerosis, including carotid intimal-medial thickness (cIMT) for assessing subclinical atherosclerosis and carotid-femoral pulse wave velocity (cfPWV) for measuring arterial stiffness, are well established and validated in adults [1, 2]. However,...
Conference Abstract
P13 Role of Adipose Tissue and Skeletal Muscle in Peripheral Arterial Disease
Joana Ferreira, Pedro Cunha, Alexandre Carneiro, Cristina Cunha, Cristina Silva, Isabel Vila, Amílcar Mesquita, Jorge Cotter
Pages: S56 - S56
Background: Peripheral arterial disease (PAD) is a manifestation of atherosclerosis. Adipose tissue (AT) and skeletal muscle (SM) are endocrine organs with vascular effects. The objective is to compare the quantity and function of AT and SM between two groups: intermittent claudication (IC) and critical...
Conference Abstract
P.33 Changes in Blood Pressure, Pulse Wave Velocity and Augmentation Index Induced by Postural Changes and Exercise
Enrique Rodilla, José Chordá, Andrea Gea, Jose Antonio Costa
Pages: S56 - S56
Objectives: To determine how orthostatic changes in body position alter BP and estimation of pulse wave velocity (PWV) and Augmentation Index (AIx), when changing from supine to the sitting position [1]. Also, to analyze the effect of a short physical exercise and of physical training status on PWV/AIx...
Conference Abstract
P15 Reference Intervals of 24-hour Central Blood Pressure Assessed with an Oscillometric Device in Healthy Children and Adolescents
Igor Posokhov, Alexandr Sharykin, Inna Trunina
Pages: S57 - S58
Reference intervals (RI) of 24-h central blood pressure (24CBP) obtained from large healthy population are lacking in Russia. We had to generated 24CBP percentile curves and RI adjusted to each level of age and/or body height and gender of each time of monitoring (24-h, daytime or nighttime). Our database...
Conference Abstract
P.34 Preeclampsia Leads to the Delayed Development of Sympathetic Control of the Cardiovascular System in the Offspring
Ekaterina Selivanova, Anastasia Shvetsova, Victoria Potekhina, Dina Gaynullina, Anna Borzykh, Oxana Kiryukhina, Vladislav Kuzmin, Olga Tarasova
Pages: S57 - S57
Background: Preeclampsia is a common pregnancy disease characterized by hypertension and kidney failure. Recent studies have shown that even in the case of successful delivery, preeclampsia could induce long-term effects in the offspring. Nevertheless, the effects of preeclampsia on the cardiovascular...
Conference Abstract
P.35 TASK-1 Channels Play an Anticontractile Role in Rat Septal Coronary Artery Under Pharmacological Blockade of Endothelium
B.S. Varvara Lazarenko, Anastasia Shvetsova, Dina Gaynullina, Rudolph Schubert
Pages: S58 - S58
Purpose/Background/Objectives: TASK-1 (TWIK-related acid-sensitive potassium) channels conduct background K+ currents in smooth muscle cells of pulmonary arteries suppressing vasocontraction. However, the vasomotor role of TASK-1 channels in systemic arteries as well as their regulation by the endothelium...
Conference Abstract
P16 Assessment of Plaque Vulnerability Using a Novel Technique: Multi-spectral Photoacoustic Imaging (CVENT-PAI)
Yuki Imaizumi, Hasan Obeid, Pierre Julia, David Calvet, Pierre Boutouyrie
Pages: S59 - S59
Background: Identification of intraplaque haemorrhage using magnetic resonance imaging (MRI) is expensive, technically demanding and sometimes uncomfortable. Photoacoustic imaging (PAI) is a new non-invasive technique combining multi-wavelength infrared laser light and ultrasound (US) imaging, able to...
Conference Abstract
P.37 An Assessment of Potential Sources of Error that May Arise in the Measurement of Carotid-Femoral Pulse Wave Velocity
James Cox, Isabella Tan, Alberto Avolio, Mark Butlin
Pages: S59 - S59
Objectives: Carotid-femoral pulse wave velocity (cfPWV) approximates aortic stiffness and is a predictor of cardiovascular events. Despite the literature highlighting the clinical relevance of cfPWV, there is minimal integration of this parameter in clinical assessments. An underlying reason may stem...
Conference Abstract
P17 Comparisons of Carotid-femoral Pulse Wave Velocity Obtained from the Surface-distance Measurement and from the Population-derived Distance Formula: Associations with Macro- and Microvascular Alterations in Older Adults
Kunihiko Aizawa, Francesco Casanova, Dave Mawson, Kim Gooding, Salim Elyas, Damilola Adingupu, David Strain, Phillip Gates, Angela Shore
Pages: S60 - S60
Introduction: Inaccurate determination of arterial path-length by surface-distance (SD) measurement is an inherent source of error in calculating carotid-femoral pulse wave velocity (CFPWV). A recent development in calculating arterial path-length by a simple distance formula (DF) for CFPWV has been...
Conference Abstract
P.38 Comparison of Arterial Hemodynamics in Early Vascular Aging (EVA), Average Vascular Aging (AVA) and Healthy Vascular Aging (HVA)
Chen-hua Lin, Hao-Min Cheng, Yu-Ting Ko, Li-Ning Peng, Liang-Kung Chen, Chen-Huan Chen
Pages: S60 - S60
Background: Large artery stiffening, as indexed by carotid-femoral pulse wave velocity (cfPWV), may vary substantially among individuals. The present study aimed to characterize the arterial mechanical properties of the macro- and microvasculature in subjects with early or healthy vascular aging (EVA,...
Conference Abstract
P18 Vascular Aging Index of the Finger Photoplethysmogram: A Validation Study with Vascular Stiffness, Mental Stress, and Day-to-Day Variability
Takashi Tarumi, Takayuki Yamabe, Jun Sugawara
Pages: S61 - S61
Background: Daily assessment of vascular health may predict cardiovascular incidence. Vascular aging index (VAI) calculated from second derivative of photoplethysmogram (SDPTG) is a simple, non-invasive measure possibly reflecting vascular stiffness. However, the effects of daily life events such as...
Conference Abstract
P.39 The Role of Advanced Glycation End Products in Vascular Ageing. Which Parameter is the Most Suitable as Biomarker?
Otto Mayer, Július Gelžinský, Jitka Seidlerová, Jan Filipovský
Pages: S61 - S61
Background: Advanced glycation end products (AGEs) are involved into several pathophysiologic processes in vascular diseases, including progressive loss of elasticity of vessel wall (arterial stiffness). Circulating soluble receptor for AGEs (sRAGE) act as a decoy and counterbalanced the harmful properties...
Conference Abstract
P19 Upper Arm Cuff Inflation Induces Reactive Changes in Systolic Blood Pressure that Could Influence Diagnosis in Some Individuals
Louisa Morris, Dean Picone, Matthew Armstrong, Martin Schultz, James Sharman
Pages: S62 - S62
Introduction: Clinic blood pressure (BP) is performed by inflation of an upper-arm cuff, but this itself may induce a reactive change in BP that could influence diagnosis. This study aimed to determine if a reactive BP change to cuff inflation occurs.
Methods: Cuff BP and beat-to-beat invasive aortic...
Conference Abstract
P.40 Ambulatory Measurement of Carotid Stiffness with a Novel Accelerometric System
R. Arathy, P.M Nabeel, Joseph Jayaraj, V.V Abhidev, Sivaprakasam Mohanasankar
Pages: S62 - S62
Purpose: Arterial stiffness is a well-established marker for cardiovascular health assessment. Current methods rely on expensive imaging systems and specialised operators to perform local stiffness evaluation from the common carotid artery (CCA) and cannot be used for ambulatory monitoring in chronic...
Conference Abstract
P20 Spontaneous Recanalization of the Internal Carotid Artery
Blanka Varnai, Gábor Simonyi, Andrea Rapcsányi, Ervin Finta
Pages: S63 - S63
Objectives: The occlusion of the internal carotid artery (ICA) frequently leads to stroke and develops most commonly as a consequence of arterial embolism or atherosclerotic thrombosis. Following acute care, if the patient’s general condition makes it possible, the patient is emitted from the hospital...
Conference Abstract
P.41 Measurement of Pressure-dependent Intra-Beat Changes in Carotid Pulse Wave Velocity using Image-Free Fast Ultrasound
Kiran V Raj, P M Nabeel, Jayaraj Joseph, Dinu Chandran, Mohanasankar Sivaprakasam
Pages: S63 - S63
Background: The clinical significance of pressure-dependent intra-beat changes in local pulse-wave velocity (C) has recently come to light [1]. While reported methods require arterial pressure and diameter measurements from a single site to assess intra-beat changes in C, we present an image-free fast...
Conference Abstract
P21 The Association of Vitamin K Antagonists with Aortic Arch Calcification in Acute Coronary Syndrome Patients
Konstantia-Paraskevi Gkini, Dimitrios Terentes-Printzios, Charalambos Vlachopoulos, Aggeliki Rigatou, Vasiliki Gardikioti, Evangelia Sigala, Dimitrios Tousoulis
Pages: S64 - S64
Purpose /Background /Objectives: Vitamin K antagonists (VKA) aggravate vascular calcifications burden, especially in haemodialysis patients potentially compounding their cardiovascular risk. We sought to investigate the relationship between VKA intake and aortic arch calcification (AAC) in patients with...
Conference Abstract
P.42 The Effects of Chemotherapy on Arterial Stiffness in Patients with Hodgkin Lymphoma
Constantinos Anagnostopoulos, Stavroula Giannouli, Nikolaos Ioakimidis, Paulos Kafouris, Iosif Koutagiar, Anastasia Sioni, Eirini Solomou, Dimitrios Terentes-Printzios, Dimitrios Tousoulis, Charalampos Vlachopoulos
Pages: S64 - S64
Introduction: Malignancies and cardiovascular disease are the two leading causes of mortality worldwide [1]. While there is extensive literature describing the cardiotoxic effects of chemotherapy on left ventricular systolic function [2,3], there is only little evidence regarding chemotherapy effects...
Conference Abstract
P22 Central and Peripheral Contributions to Submaximal Exercise Performance in Older Adults in the SouthAll and Brent REvisited (SABRE) Study
Siana Jones, Martin Schultz, Therese Tillin, Suzanne Williams, Nishi Chaturvedi, Alun Hughes
Pages: S65 - S65
Background: Functional capacity declines with age leading to disability and increased cost of health and social care. In older adults, factors that influence the ability to sustain sub-maximal exercise (a marker of functional capacity) are not well defined. We aimed to determine the contribution of cardiac...
Conference Abstract
P.43 The Association Between Early Vascular Aging and Cyclothymic Affective Temperament
Milan Vecsey-Nagy, Bálint Szilveszter, Márton Kolossváry, Xénia Gonda, Zoltán Rihmer, Béla Merkely, Pál Maurovich-Horvat, János Nemcsik
Pages: S65 - S65
Objectives: Affective temperaments (depressive, anxious, irritable, hyperthymic, cyclothymic) are regarded as the biologically stable core of personality, and accumulating data implies their relationship with cardiovascular diseases. There are currently limited data on the association of affective temperaments...
Conference Abstract
P23 Tadalafil improves hemodynamic parameters and arterial stiffness in patients with grade I-II obesity without comorbidities
Mariana Larios-Cardenas, Fernando Grover-Páez, David Cardona-Muller, Ernesto Cardona, Oscar I. Gonzalez-Radillo, Jonathan Trujillo-Quiros, Marycruz Barocio-Pantoja, Patricia Quezada-Fernandez, Carlos G. Ramos-Becerra
Pages: S66 - S66
Background: Obesity is a global health problem, it is associated with diabetes, hypertension, and cardiovascular diseases [1] and negative hemodynamic effects have been observed [2]. Tadalafil has shown an improvement in endothelial function [3] the aim of the present investigation was to evaluate its...
Conference Abstract
P.44 Application of an Algorithm Developed for Measuring Gastrointestinal Motility to the Assessment of Arterial Mechanical Properties
Andrew Bard, Stephen Greenwald, Sandip Sarkar
Pages: S66 - S67
Background: GIQuant (Motilent, London) is an algorithm for analysing cine-MRI, using the displacement fields generated by registration of indivisdual ciné frames. It produces a summary of how much movement occurs (“motility”) for anatomical locations within a reference image [1]. Although it is used...
Conference Abstract
P24 Restored Physiological Local Carotid Pulse Wave Velocity After Bariatric Surgery in Obese Subjects
Alessandro Giudici, Carmela Morizzo, Michaela Kozakova, Lorenzo Losso, Carlo Palombo, Kennedy J. Cruickshank, Ashraf Khir
Pages: S67 - S67
Obesity is a risk factor for cardiovascular events and is associated with increased arterial stiffness [1,2]. However, the effect of drastic changes in Body Mass Index (BMI) on arterial mechanics has not been fully investigated. Our study aimed at evaluating changes in local carotid PWV (cPWV) in obese...
Conference Abstract
P25 Effect of Live-firefighting on Ventricular-vascular Coupling
Brooks Hibner, Elizabeth Schroeder, Wesley Lefferts, Thessa Hilgenkamp, Huimin Yan, Gavin Horn, Denise Smith, Bo Fernhall
Pages: S68 - S68
Introduction: Cardiovascular events are the leading cause of death among firefighters, with the greatest risk occurring during or shortly after fire suppression activity. Increased cardiovascular risk potentially manifests from detrimental changes in ventricular function, vascular load, and their interaction...
Conference Abstract
P.45 Characterization of the Microcirculatory Response to Gravity-Induced Changes using Thermal Imaging
Noam Moyal, Noa Darchi, Oshrit Hoffer, Neta Rabin, Benjamin Gavish, Moshe Halak, Zehava Ovadia-Blechman
Pages: S68 - S68
Objective: The goal of this study was to characterize the changes in the palm’s blood distribution in response to a decrease in blood pressure due to gravity-induced changes, using thermal imaging.
Methods: Thermal hands images were taken from ten healthy volunteers, without any known vascular pathologies,...
Conference Abstract
P26 Ascending Aorta Longitudinal Strain is not Altered in Bicuspid Aortic Valve Patients
Andrea Guala, Lydia Dux-Santoy, Gisela Teixido-Tura, Aroa Ruiz-Muñoz, Laura Madrenas, Minerva Gandara, Augusto Sao-Aviles, Filipa Valente, Laura Galian-Gay, Laura Gutierrez, Teresa Gonzalez-Alujas, Ignacio Ferreira, Arturo Evangelista, Jose Rodriguez-Palomares
Pages: S69 - S69
Background: Impaired ascending aorta (AAo) longitudinal strain, a marker of AAo deformation due to aorto-ventricular mechanical interaction, is related to progressive dilation and aortic events in Marfan syndrome [1]. Whether the high prevalence of dilation in bicuspid aortic valve (BAV) is due to intrinsically-altered...
Conference Abstract
P.46 Assessment of Intraplaque Hemorrhage by Photoacoustics Imaging (PAI): First in-vivo Human Validation Study
Rosa Maria Bruno, Yuki Imaizumi, Hasan Obeid, Michael Jaeger, Pierre Julia, Patrick Bruneval, David Calvet
Pages: S69 - S69
Aim: To validate a photoacoustic imaging (PAI) system, for the identification of intraplaque hemorrhage, comparing it with MRI and histology (gold standard).
Methods: 25 patients with carotid stenosis >70% and clinical indication to tromboendoarterectomy were recruited. Angio-MRI for intraplaque...
Conference Abstract
P27 Non-validated Blood Pressure Devices Dominate the Online Marketplace: An Initiative of the Lancet Commission on Hypertension Group
Dean Picone, Rewati Deshpande, Martin Schultz, Ricardo Fonseca, Norm Campbell, Christian Delles, Michael Hecht-Olsen, Aletta Schutte, George Stergiou, Sonia Angell, Raj Padwal, James Sharman
Pages: S70 - S70
Introduction: Home BP monitoring is recommended to guide clinical decisions on hypertension and is used worldwide. People make their own decisions when purchasing BP measurement devices, which are often made online. One potential barrier to accurate home BP monitoring is that patients may purchase an...
Conference Abstract
P.47 Feasibility Evaluation of Imaging-Free Ultrasound Technology to Measure Diameters of Brachial and Radial Arteries for Assessment of Endothelial Function
Dinu Chandran, Jayaraj Joseph, Sakshi Sen, Kiran Raj, P.M. Nabeel, Kishore Kumar Deepak
Pages: S70 - S70
Background: Ultrasonographic imaging to record changes in peripheral arterial diameter associated with Flow mediated dilatation or Low flow mediated constriction is routinely used to assess various facets of vascular endothelial function. Imaging poses many challenges including requirement of costly...
Conference Abstract
P28 A Commonly Used Single-item Physical Activity Question Fails to Discriminate Expected Blood Pressure-related Cardiovascular Risk in a General Community Sample
Martin Schultz, Dean Picone, Ricardo Fonseca, James Sharman
Pages: S71 - S71
Background: Completion of ≥150 minutes/week of physical activity (PA) is recommended for cardiovascular health, but this is achieved only by ~50% of Australian adults. Assessing self-reported PA via quick single-item question is desirable for large-scale cardiovascular research and health screening....
Conference Abstract
P.48 Ultrasound-Based Velocity and Acceleration of the Carotid Atheromatous Plaque in Asymptomatic Patients with Moderate and Severe Stenosis
Kalliopi Dalakleidi, Spyretta Golemati, Aimilia Gastounioti, Christos Liapis, Konstantina Nikita
Pages: S71 - S71
Purpose: The purpose of this study was to investigate differences in ultrasound-based velocities and accelerations of the carotid atheromatous plaque between asymptomatic patients with moderate and severe stenosis, based on the assumption that plaque motion features are sensitive to cardiovascular health...
Conference Abstract
P30 Interplay of Genetic and Environmental Factors Determining Carotid and Femoral Intima-media Thickness and Plaques
Adam Domonkos Tarnoki, Rebeka Debreceni, Greta Janositz, Kata Gyulay, Jokkel Zsofia, Viktor Berczi, Helga Szabo, Anita Hernyes, David Laszlo Tarnoki
Pages: S72 - S72
Introduction: Intima-media thickness (IMT) of carotid and femoral artery and plaque formation are both markers of subclinical cardiovascular risk, despite these two process are not simultaneous. Our aim was to investigate their genetic and environmental background.
Methods: 54 monozygotic (MZ) and 32...
Conference Abstract
P.49 Aortic Root Longitudinal Strain by Speckle-Tracking Echocardiography: Comparison with Cardiac Magnetic Resonance and Predictive Value in Marfan Syndrome Patients
Andrea Guala, Maria Isabel Pons, Aroa Ruiz-Muñoz, Lydia Dux-Santoy, Laura Madrenas, Minerva Gandara, Filipa Valente, Angela Lopez-Sainz, Laura Galian, Laura Gutierrez, Augusto Sao-Aviles, Teresa Gonzalez-Alujas, Ignacio Ferreira, Arturo Evangelista, Jose Rodriguez-Palomares, Gisela Teixido-Tura
Pages: S72 - S72
Background: Low longitudinal strain of the ascending aorta (AAo) by cardiac magnetic resonance (CMR) predicts dilation and aortic events in Marfan syndrome (MFS) [1], possibly reflecting aortic stiffness [2]. Speckle-tracking is established for cardiac deformation, but proximal aorta applications are...
Conference Abstract
P31 Aldosterone and Cardiovascular Function in a Young Cohort: The African-PREDICT Study
Johannes Van Rooyen, Lebo Gafane-Matemane, Hugo Huisman, Carina Mels, Alta Schutte
Pages: S73 - S73
Objectives: High levels of aldosterone may contribute to early development of hypertension. The aim was to evaluate the influence of high serum aldosterone on cardiovascular function in healthy black and white South Africans.
Methods: This study was embedded in the African-PREDICT study, included 233...
Conference Abstract
P.50 Radial Artery Phenotyping in Fibromuscular Dysplasia Through Ultra-High Frequency Ultrasound: A Radiomic Approach
Federica Poli, Rosa Maria Bruno, Francesco Faita, Hakim Khettab, Michel Azizi, Saverio Vitali, Mirco Cosottini, Davide Caramella, Lorenzo Ghiadoni, Stefano Taddei, Pierre Boutouyrie, Alexandre Persu, Xavier Jeunemaitre, Aurélien Lorthioir
Pages: S73 - S73
Rationale and Aim: This study is aimed at identifying possible patterns of vascular wall disarray and remodeling in radial arteries of patients with fibromuscular dysplasia (FMD), by means of ultrahigh frequency ultrasound (UHFUS).
Methods: UHFUS scans of the radial arteries and of 30 FMD patients and...
Conference Abstract
P32 Nationwide Comprehensive Health Protection Screening Program in Hungary 2010-2020-2030
István Barna, Ede Kékes, Gergely Dankovics, Tennó Daiki
Pages: S74 - S74
From 2010 a new, complex screening program started in Hungary, it works with the support of 76 professional-scientific societies and companies. Within the framework of the Program in the largest mobile diagnostics center in Hungary 37 comprehensive surveys in free form. This enormous special screening...
Conference Abstract
P.53 Ascending Aorta Diameter and Pulse Wave Velocity are Increased and Local Hemodynamic is Disrupted in Patients with Blunt Traumatic Thoracic Aortic Injury Treated by TEVAR
Andrea Guala, Daniel Gil Sala, Aroa Ruiz-Muñoz, Marvin Garcia-Reyes, Lydia Dux-Santoy, Gisela Teixido-Tura, Cristina Tello, Filipa Valente, Angela Lopez-Sainz, Laura Galian, Laura Gutierrez, Kevin Johnson, Oliver Wieben, Ignacio Ferreira, Arturo Evangelista, Sergi Bellmunt-Montoya, Jose Rodriguez-Palomares
Pages: S74 - S75
Background: Thoracic endovascular aortic repair (TEVAR) is becoming the preferred treatment option to repair the proximal descending aorta after rupture following blunt traumatic injury. However, hemodynamic and mechanic implications of this intervention are poorly understood. Exploiting the possibilities...
Conference Abstract
P34 24-Hour Ambulatory Brachial Versus Aortic Systolic Blood Pressure: Relationship with Left Ventricular Mass Significantly Differs. Pooled Results from the International 24 Hour Aortic Blood Pressure Consortium (i24ABC)
Siegfried Wassertheurer, Athanase Protogerou, James Sharman, Enrique Rodilla Sala, Piotr Jankowski, Maria Lorenza Muiesan, Cristina Giannattasio, Bernhard Hametner, Jose Maria Pascual, Robert Zweiker, Antonio Argyris, Anna Paini, Ian Wilkinson, Danuta Czarnecka, Massimo Salvetti, Alessandro Maloberti, Carmel McEniery, Yan Li, Janos Nemcsik, Giacomo Pucci, Cornelia Ablasser, Jacques Blacher, Alexandre Valleé, Alejandro de la Sierra, Yi Zhang, Hongwei Ji, Barry McDonnell, Marco Mota, Annelise Paiva, Andrea Brandao, Thomas Weber
Pages: S75 - S75
Background: There is evidence of a closer relation between 24 hour aortic systolic blood pressure (aSBP) and left ventricular mass (LVM) compared with 24 hour brachial SBP. However, sample sizes are relatively small and there is some inconsistency in findings. We sought to address this by pooling data...
Research Article
P35 Education Level may Modify the Association Between Cardiac Index and Cognitive Function Among Elders with Normal Ejection Function
Cheng Hao-Min, Chuang Shao-Yuan, Ko Yu-Ting, Liao Chao-Feng, Pan Wen-Harn, Liu Wen-Ling, Hung Chen-Ying, Chen Chen-Huan
Pages: S76 - S76
Background: Lower cardiac index (CI) in elders without clinical heart disease has been associated with impaired cognitive function and incident dementia. In the present study, we investigated the modulating effects of education level and arterial stiffness on the association between CI and cognitive...
Conference Abstract
P.54 Biomarkers and Haemodynamic Predictors of Left Atrial Strain in Early Hypertension
Maryam Bukhamseen, Nada Al-Saileek, Ahmed Al-Saileek, Mohammad Ghormalla Ghamdi, Tahlil Wasame, Ahmed Omran, Azra Mahmud
Pages: S76 - S76
Background: In the early stages of atrial remodeling, increased aortic stiffness might indicate atrial fibrosis.
Objective: This study aimed to investigate the association between left atrial (LA) mechanical function, assessed by two-dimensional speckle tracking echocardiography and aortic stiffness...
Conference Abstract
P36 Leukocyte Telomere Length is Inversely Associated with Wave Reflection in 566 Normotensive and Never-treated Hypertensive Subjects
Ilkka Pörsti, Milja Honkonen, Kati Vääräniemi, Outi Saijonmaa, Antti Tikkakoski, Jenni Koskela, Arttu Eräranta, Mika Kähönen, Jukka Mustonen, Frej Fyhrquist
Pages: S77 - S77
Background: Telomeres are short segments in chromosome ends, the length of which is reduced during cell life-cycles. We examined the association of leukocyte telomere length and short telomere proportion with hemodynamic variables.
Methods: Altogether 566 subjects (279 women and 287 men) without cardiovascular...
Conference Abstract
P.55 Dietary Nitrate Prevents Progression of Carotid Subclinical Atherosclerosis Through BP-Independent Mechanisms in Patients with or at Risk of Type 2 Diabetes Mellitus: Results from the Double-Blind, Randomized-Controlled, Factorial Vasera Trial
Franca Morselli, Luca Faconti, Charlotte E Mills, Steve Morant, Philip J Chowienczyk, J Kennedy Cruickshank, Andrew J Webb, Alessandro Cavarape
Pages: S77 - S77
Background: Epidemiological and animal studies suggest the potential of dietary nitrate (NO 3−) to inhibit atherogenesis. Spironolactone may improve arterial stiffness. We tested if 6 months’ intervention with dietary nitrate and spironolactone could affect carotid subclinical atherosclerosis and stiffness...
Conference Abstract
P37 Increased Pressure Dependency of Pulse Wave Velocity with Age
Andrii Boguslavskyi, Haotian Gu, Lingyun Fang, Ana Rita Cabrito Cobaco, Philip Chowienczyk
Pages: S78 - S78
Background: Arterial stiffness, as measured by pulse wave velocity (PWV) is dependent on arterial blood pressure but whether this dependence varies with age is unknown. The objective of this study was to determine to what degree pressure-dependence varies with age.
Methods: 83 heathy (43 females) normotensive...
Conference Abstract
P.56 Differences in Vascular Effects Between One Session of Moderate-Intensity Continuous Physical Exercise and High-Intensity Interval Physical Exercise in Individuals with High Blood Pressure
Sara Rodrigues, Renata G S Verardino, Marcel J A Costa, Ana Luíse Duenhas-Berger, Valéria Costa-Hong, Luiz A Bortolotto
Pages: S78 - S78
Purpose: To compare augmentation index (AIx) between one Moderate-intensity continuous physical exercise (MICPE) and one High-intensity interval physical exercise (HIIPE) session in normal/high normal blood pressure (BP) (120–140 for systolic and 80–90 mmHg for diastolic). Additionally, to compare two...
Conference Abstract
P38 Association of Daytime Augmentation Index with Brain-derived Neurotrophic Factor in Untreated Hypertensive Patients
János Nemcsik, Dóra Batta, Beáta Kőrösi, Zsófia Nemcsik-Bencze, Andrea László, Lilla Lénárt, Andrea Fekete
Pages: S79 - S79
Brain-derived neurotrophic factor (BDNF) is a neurotrophic molecule with impact on microvasculature and also with complex psychosomatic connections. The aim of our study was to evaluate its associations with 24-hour brachial and central hemodynamic parameters and arterial stiffness in untreated patients...
Conference Abstract
P.57 Acetylsalicylic Acid Reduces Passive Aortic Wall Stiffness and Cardiac Remodelling in a Mouse Model of Advanced Atherosclerosis
Lynn Roth, Wim Martinet, Guido R.Y. De Meyer
Pages: S79 - S80
Background: Acetylsalicylic acid (ASA) is used in secondary prevention of cardiovascular disease (CVD) because of its antithrombotic effects. We investigated whether ASA has additional therapeutic value by preventing the progression of inflammation and cardiovascular remodelling in mice with stable atherosclerosis...
Conference Abstract
P40 Arteriovenous Fistula, Blood Pressure and Arterial Reservoir-wave Analysis: Lessons From End-stage Renal Disease
Mathilde Paré, Rémi Goupil, Catherine Fortier, Fabrice Mac-Way, Karine Marquis, Bernhard Hametner, Siegfried Wassertheurer, Martin Schultz, James E. Sharman, Mohsen Agharazii
Pages: S80 - S80
Purpose/Background/Objectives: According to reservoir-wave theory, excess pressure (XSP) is analogous to flow and related to excess cardiac workload. In end-stage renal disease (ESRD) patients, we have shown that XSPI is associated with increased mortality and is higher in patients with arteriovenous...
Conference Abstract
P41 24 h Arterial Stiffness Measurement on Healthy and COPD Patients
R. M. Böcskei, B. Benczúr, A. Bikov, Cs. Böcskei, A. Bohács, R. Husznai, A. Cziráki
Pages: S81 - S81
Introduction: Chronic obstructive pulmonary disease (COPD) is currently one of the leading causes of death worldwide. COPD frequently occur together with cardiovascular disease. The coexistence of the two diseases are associated with worse outcomes than either condition alone. ABPM and 24 h arterial...
Conference Abstract
P.58 Genetic Background Dictates Aortic Fibrosis in Hypertensive Mice
Bart Spronck, Marcos Latorre, Sameet Mehta, Alexander W. Caulk, Abhay B. Ramachandra, Sae-Il Murtada, Alexia Rojas, Chang-Sun He, Bo Jiang, Mo Wang, Matthew R. Bersi, George Tellides, Jay D. Humphrey
Pages: S81 - S82
Background: Many genetic mutations affect aortic structure and function in mice, but little is known about the influence of background strain. We compared the biomechanical, structural, and gene expression responses of C57BL/6J and 129SvEv aortas to angiotensin II (AngII)-induced hypertension.
Methods:...
Conference Abstract
P42 Correlation Between Neck Circumference and Pulse Wave Velocity in a Population Based Study in Salvador-Brazil, Preliminary Results
Larissa Bessa, Roberta Cunha, Lucélia Magalhães, Diorlene da Silva, Antônio Filho, Rodrigo Lima, Grupo Vascor
Pages: S82 - S82
Introduction: Pulse wave velocity (PWV) is considered a gold standard for assessment of arterial stiffness [1]; neck circumference (NC) is a good anthropometrical indicator of fat accumulation in the upper body region [2].
Methods: A population-based cross-sectional study representative of a neighborhood...
Conference Abstract
P43 The Association of Irritable Affective Temperament with 24-Hour Brachial and Central Blood Pressure and Hemodynamic Parameters in Untreated Hypertensive Men
Beáta Kőrösi, Dóra Batta, Milan Vecsey-Nagy, Xenia Gonda, Zoltán Rhimer, Zsófia Nemcsik-Bencze, Andrea László, János Nemcsik
Pages: S83 - S83
Background: Affective temperaments (depressive, irritable, hyperthymic, anxious, cyclothymic) have important role in psychopathology, but cumulating data support their involvement in vascular pathology, especially in hypertension as well. The aim of our study was to evaluate their associations with 24-hour...
Conference Abstract
P.60 Improvement in Muscular Strength Within One Year is Associated with Increased Arterial Stiffness in Young Male Soccer Players
MPH Lisa Baumgartner, Heidi Weberruß, Katharina Appel, Tobias Engl, Renate Oberhoffer-Fritz, Thorsten Schulz
Pages: S83 - S83
Purpose: The adaptation process of the cardiovascular system to exercise and muscular strength in young athletes is unclear. Therefore, we investigated the influence of changes in muscular strength and weekly training load within one year on arterial stiffness in young male soccer players.
Methods:...
Conference Abstract
P44 Spureous Systolic Hypertension or a Defined Arterial Stiffness Phenotype
Pedro Forcada, Miguel Sangiovanni, Wanda Pampinella, Oscar Montaña
Pages: S84 - S84
Background: High systolic blood pressure in young individuals with normal central pressure has been described as “Spureous Systolic Hypertension” and there is a strong controversy if it is a normal or pathologic condition.
Objective: To compare young adult patients (20–40 y.o.) with isolated systolic...
Conference Abstract
P.61 Impact of Kidney Transplantation on Arterial Reservoir-Wave Analysis
Nadège Côté, Emy Philibert, Mathilde Paré, Rémi Goupil, Catherine Fortier, Martin G. Schultz, James E. Sharman, Mohsen Agharazii
Pages: S84 - S84
Purpose/Background/Objective: According to reservoir-wave approach (RWA) arterial pressure is the sum of a reservoir pressure (RP) accounting for dynamic storage and release of blood from arteries, and an excess pressure (XSP) analogous to flow. RP is the minimal left ventricular work required to generate...
Conference Abstract
P45 Comparison of Systemic and Regional Vascular Parameters Using New Ultrasound Techniques: Are they Clinically Useful?
Pedro Forcada, Miguel Sangiovanni, Wanda Pampinella, Oscar Montaña
Pages: S85 - S85
Background: US is a simple, reproducible and economic technique for vascular evaluation. New technologies using radiofrequency and multidimensional Doppler plus computer development allow to evaluate parameters like shear stress, Flow profile and vascular remodeling no invasively.
Objective: To compare...
Conference Abstract
P.62 Assessment of Isoflavone and Ethanolic Extract of Inonotus Obliquus on Experimentally Induced Diabetes
Kingsley Duru, Cara Hildreth, Alberto P. Avolio, Jacqueline K. Phillips, Mark Butlin
Pages: S85 - S85
Purpose: Studies support beneficial effects of isoflavones, but antidiabetic effects of these agents remains unconfirmed [1,2]. This pilot study investigates isoflavones and Inonotus obliquus (chaga) extract effects on diabetes.
Methods: Diabetes was induced (streptozotocin 65 mg/kg, nicotinamide 110...
Conference Abstract
P46 Haemodynamics Determinants of Central Pressure during Systole
Samuel Vennin, Ye Li, Jorge Mariscal-Harana, Haotian Gu, Henry Fok, Jordi Alastruey, Phil Chowienczyk
Pages: S86 - S86
The influence of arterial and ventricular parameters on the main fiducial pressure points and index during systole has been investigated using a mix of in silico and in vivo data. Notably, an index, QIx, based entirely on ventricular ejection patterns has been developed and its potential in describing...
Conference Abstract
P.63 Sarcopenia and Atherosclerotic Occlusive Disease: How Much We Know and What We Need to Know About this Association?
Joana Ferreira, Alexandre Carneiro, Pedro Cunha, Armando Mansilha, Isabel Vila, Cristina Cunha, Cristina Silva, Adhemar Longatto-Filho, Maria Correia-Neves, Gustavo Soutinho, Luís Meira-Machado, Amilcar Mesquita, Jorge Cotter
Pages: S86 - S87
Purpose/Background: Sarcopenia (decrease of muscle mass and function) has been linked with atherosclerosis [1]. The EWGSOP2 updated consensus, uses low muscle strength as the primary indicator of sarcopenia [2]. It is acknowledged that strength is better than mass for predicting adverse outcomes [2]....
Conference Abstract
P47 Hypertension Prevalence in Health Sciences Students of the University of Guadalajara
Claudia Yanette Galan Ruiz, David Cardona Müller, Ernesto Germán Cardona Muñoz, Sylvia Elena Totsuka Sutto, Brandon Giovany Illescas Vidrio, Fernando Grover Páez, Carlos Gerardo Ramos Becerra
Pages: S87 - S87
Hypertension (HTN) is considered within the first 9 preventable causes of death in Mexico [1]. In order to estimate HTN prevalence in students a blood pressure (BP) measuring campaign was performed at the University of Guadalajara.
Methods: BP was measured in morning shift students, none with known...
Conference Abstract
P48 Effects of Remote Ischaemic Preconditioning on Haemodynamic and Arterial Stiffness Parameters in Patients Undergoing Lower Limb Angiographic Procedure
Karl Kuusik, Teele Kepler, Mihkel Zilmer, Jaan Eha, Mare Vähi, Kaido Paapstel, Jaak Kals
Pages: S88 - S88
Objectives: Remote ischaemic preconditioning (RIPC) is a phenomenon that promotes protection of tissues and organs against ischaemia-reperfusion injury. RIPC has been shown to reduce myocardial and renal injury but its effect on arterial stiffness in patients undergoing lower limb digital subtraction...
Conference Abstract
P.64 Active Vitamin D Treatment Does Not Improve Arterial Stiffness and Markers of Cardio-Renal Risk in Patients with Type 2 Diabetes and Stage 3 Chronic Kidney Disease: a Randomised Controlled Trial
Nikolaos Fountoulakis, Salma Ayis, Anastasios Mangelis, Angeliki Panagiotou, Maria Flaquer, Stanimir Stoilov, Giuseppe Maltese, GianCarlo Viberti, Stephen Thomas, Luigi Gnudi, Janaka Karalliedde
Pages: S88 - S88
Background and Aims: Active vitamin D [1,25(OH)2D3] deficiency is a potential modifiable risk factor for cardiovascular (CVD) and renal disease in patients with type 2 diabetes (T2DM) and stage 3/4 chronic kidney disease (CKD). Exact mechanisms are unclear. Arterial stiffness is an independent predictor...
Conference Abstract
P49 Experimental Flow Visualization of a Flow Diverting Stent in a Popliteal Aneurysm
Lennart van de Velde, Michel Reijnen, Michel Versluis, Joerg Tessarek, Erik Groot Jebbink
Pages: S89 - S90
Purpose: Flow diverting stents are commonly used in saccular cerebral aneurysms [1]. Their use has not yet been investigated for popliteal aneurysms, which are commonly fusiform in nature and exposed to pulsatile triphasic flows. We have shown the clinical feasibility of flow diverters in a pilot study...
Conference Abstract
P.65 Increased Biomarkers of Endothelial Dysfunction and Thrombotic Microenvironment in Patients with Autoimmune Rheumatic Disorders Free from Cardiovascular Comorbidities
Eleni Gavriilaki, Panagiota Anyfanti, Stella Douma, Eugenia Gkaliagkousi
Pages: S89 - S89
Purpose/Background/Objectives: Cardiovascular risk is increased in patients with autoimmune rheumatic disorders [1]. Endothelial and platelet MVs (EMVs, PMVs) are small vesicles (0.1–1 μm) released from plasma membrane and represent novel markers of endothelial dysfunction and thrombosis. Their levels...
Conference Abstract
P.66 Radial Artery Systolic-Diastolic Pulse Transit Time After Kidney Transplantation
Emy Philibert, Hasan Obeid, Mathilde Paré, Nadège Côté, Catherine Fortier, Rémi Goupil, Mohsen Agharazii
Pages: S90 - S90
Purpose/Background/Objective: We have previously shown that restoration of kidney function through kidney transplantation (KTx) is associated with improved aortic stiffness. In this study, we aim to examine whether this change in aortic stiffness translates into improvement of radial artery systolic-diastolic...
Conference Abstract
P50 The Administration of Losartan/Amlodipine in Fixed Combination Versus Losartan Improves the Hemodynamic and Arterial Stiffness Parameters in Patients with Systemic Hypertension Grade 1 and 2
Mayra Jimenez, Fernando Grover, Marycruz Barocio, Ernesto Cardona, Patricia Quezada, Jhonatan Trujillo, David Cardona, Carlos Ramos
Pages: S91 - S91
Purpose/Background/Objectives: Hypertension (HAS) represents 9.4 million deaths from all the cases of cardiovascular disease worldwide [1]. The pulse wave velocity (PWV) and some hemodynamic parameters have been associated with this outcome [2,3]. Losartan, as well as amlodipine, have shown benefits...
Conference Abstract
P.67 The Effects of Chemotherapy on Arterial Inflammation Assessed by 18FDG PET-CT in Patients with Lymphoma
Constantinos Anagnostopoulos, Stavroula Giannouli, Nikolaos Ioakimidis, Paulos Kafouris, Iosif Koutagiar, Anastasia Sioni, Eirini Solomou, Dimitrios Terentes-Printzios, Dimitrios Tousoulis, Charalampos Vlachopoulos
Pages: S91 - S91
Introduction: Anti-cancer treatment can lead to increased cardiovascular morbidity among lymphoma survivors [1]. This may be the result of direct effect of treatment on heart function, or indirect acceleration of atherosclerosis. 18F-fluorodeoxyglucose (FDG) uptake is a sensitive and robust marker for...