Artery Research

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Volume 1, Issue S1, June 2006, Pages S47 - S47

P.086 EVALUATION OF ARTERIAL DISTENSIBILITY IN HYPERTENSIVE PATIENTS TREATED WITH IRBESARTAN

Authors
A. Vicente Casanova*1, J. Redón i Más2, J. Aznar Vicente3
1Hypertension Unit. Clinic Hospital, Valencia, Spain,
2Hypertension Unit. Clinic Hospital, Valencia, Spain,
3Research Unit. Marina Alta Hospital, Denia-Alicante, Spain
Available Online 13 June 2007.
DOI
10.1016/S1872-9312(07)70109-6How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Introduction: The aim of the study is to evaluate the improvement of arterial distensibility by means of: (1) decrease of pulse wave velocity (PWV); (2) decrease of SBP and PP; and (3) decrease of Blood Pressure (BP), using an Angiotensin-II receptor antagonist, Irbesartan.

Material and Methods: 97 hypertensive patients, of which 43 (45.7%) were men, who attended their primary care centres two times. Mean age was 55 (SD ±10) in men and 62 (SD ±11) in women. All patients had their BP checked with a mercury sphygmomanometer, and their PWV measured with an automatic device, Complior, which registers in two different points (carotid and femoral arteries). Both measurements were taken at the initial appointment and at the six months follow up.

Results: there was a decrease in SBP, Diastolic Blood Pressure (DBP), PP, and PWV. A significant relation between the decrease of PWV and the decrease of the SBP was found.

Conclusions: (1) The PWV can be a valid indirect method to measure the arterial elasticity decrease in clinical practice, and (2) The use of drugs that act directly on the renin-angiotensin system (Irbesartan) can be useful in improving such elasticity.

SBP DBP CF PP PWV
Appointment A1 A2 A1 A2 A1 A2 A1 A2 A1 A2
Minimum 124 111 62 62 52 55 36 40 8 7.68
Maximum 200 176 110 94 104 104 106 95 21 21.51
Mean 157.66 140.3 92.3 81.84 77.79 79.02 65.36 58.46 12.29 11.46
SD 16.01 13.36 9.09 7.82 10.58 11.65 16.45 12.62 2.9 3.1
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Journal
Artery Research
Volume-Issue
1 - S1
Pages
S47 - S47
Publication Date
2007/06/13
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/S1872-9312(07)70109-6How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - A. Vicente Casanova*
AU  - J. Redón i Más
AU  - J. Aznar Vicente
PY  - 2007
DA  - 2007/06/13
TI  - P.086 EVALUATION OF ARTERIAL DISTENSIBILITY IN HYPERTENSIVE PATIENTS TREATED WITH IRBESARTAN
JO  - Artery Research
SP  - S47
EP  - S47
VL  - 1
IS  - S1
SN  - 1876-4401
UR  - https://doi.org/10.1016/S1872-9312(07)70109-6
DO  - 10.1016/S1872-9312(07)70109-6
ID  - VicenteCasanova*2007
ER  -