The experiment was carried out according to the following scheme. In the first group (control), all wheat, barley and corn grains were fed in flattened form, in the second, third and fourth groups 50% of the wheat, barley and corn grain mass (half the daily supply) was prepared in various ways. In the...

The article raises questions concerning the reasons for the falsification of white tea varieties in Russia, the possibility of determining its authenticity by instrumental and sensory methods. The technological process and parameters of brewing leaves of white tea varieties, for example, silver tea,...

The antibacterial activity of nanostructures based on antibiotics, plant extracts and metal salts against Escherichia.coli, Staphylococcus sp. and Aspergillus niger was shown. A statistically significant increase in the inhibition effect of ceftriaxone in the poludan was shown by 33,3%, copper sulfate...

The effect of extracts of medicinal plants from the families Lamiaceae and Asteraceae on the growth and development of the bacterial culture of Escherichia coli is question for discus. The strain of Escherichia coli was chosen as the object of the study. Extracts of medicinal plants pippermint, salvia...

On the basis of SSR-method the genetic structure of marsh frog populations (Pelophylax ridibundus) in the urbanized area of Belgorod and its suburbs was studied. The data obtained indicate a high level of genetic variability in the populations studied. The heterozygosity level was equal to He=0.731±0.027,...

The purpose of study is to identify possibilities of using fruits of eleutherococcuses Eleutherococcus senticosus Rupr. & Maxim. аnd Eleutherococcus sessiliflorus Rupr. & Maxim., which are undergoing introduction tests in arboretum of N.V. Tsytsin Main Botanical Garden of Russian Academy of Science,...

The article presents the results of the research aimed at Medication Administration improving for pregnant woman with acute respiratory viral. During this social research a medical and social portrait of woman with acute respiratory viral was developed, the analysis of satisfaction and preferences in...

The article presents the concept of marketing analysis of the additional services provided in pharmacies in the city of Belgorod. The authors carried out the assessment of customers' satisfaction with the quality of the additional services provided in the pharmacies in the city of Belgorod. Also the...

The article presents the results of improving the drug supply for women with menopausal disorders at the regional level. A sociological study of women with climacteric disorders as a consumer of pharmaceutical care has been conducted. Marketing analysis of the Russian and regional pharmaceutical markets...

The article presents the results of the optimization of the drug supply for children with disorders of the autonomic nervous system (ANS) under inpatient treatment at the regional level; a socio-demographic portrait of a child affected with autonomic dysfunction syndrome has been developed; a pharmacoeconomic...

The article presents the results of a marketing research of the Russian pharmaceutical market of drugs for the treatment of weight disorders - overweight and underweight. Macrocontours have been developed, the main trends in market formation have been identified.

The aim of this paper was to study the influence on morpho-functional indicators of the organism of experimental animals by regular consumption of jelly (kissel) concentrates in industrial production in comparison with the jelly (kissel) prepared according to the set of technical standards. The impact...

The development of clean alternative biofuel, including biohydrogen, is of great significant interest. One method for biohydrogen is dark and light fermentation when hydrogenases are responsible enzymes for H2 metabolism. A further development of biotechnology for H2 production can be directed in the...

The species Sanguisorba officinalis L. is widespread in the Republic of North Ossetia-Alania and is promising for the study and practical use of the pharmacological and food industry. The aim of the work is to analyze the dynamics of biologically active substances in the phytomass S. officinalis depending...

This article studies the action and biocompatibility of the developed montmorillonite-containing preparation “Sorbent” on experimental animals with its long-term use. The local irritating effect of the “Sorbent” preparation was evaluated by its effect on the gastric mucosa of animals with experimental...

The aim of this study was to extract the volatile oils from some aromatic plants and to investigate their antimicrobial and antioxidant activities. The volatile oils were isolated from dried parts of plants by hydro distillation using a neo-Clevenger apparatus. The volatile oils of basil (Ocimum basilicum),...

The paper dwells upon treatment of surgical sepsis in dogs by extracorporeal detoxification. Data were sampled from 32 dogs of various breeds, aged 4 to 12, weighing 20 to 68 kilogram, treated against surgical sepsis at the Panacea Veterinary Hospital, Chelyabinsk; the dogs were divided into the experimental...

The study was made about parameters of fluctuating asymmetry of the birch leaf blade and amount of total soluble protein of the seed progeny of Betula pendula in areas of Central Black Earth Region in different environmental conditions. The environmental impact on trees of weeping birch and its seed...

The influence of "FITOS" BAA on the natural resistance of laying hens and their productivity was studied. It was found that it improves the physiological state of the chickens and increases egg production.

This article provides the rationale for the pharmacological correction of non-alcoholic fatty liver disease. This is due to the fact that non-alcoholic steatohepatosis of the liver is a slowly progressing disease. Most often, non-alcoholic steatohepatosis progresses to non-alcoholic steatohepatitis,...

The purpose of this study was to develop a method of quali-tative and quantitative assessment of biologically active sub-stances of P. fruticosa L. herb. As object of study was used P. fruticosa L. herb. We used the method of high performance liquid chromatography in reversed-phase variant. As a result...

the purpose of the present study was a comparative study of the ability of some freons to extract the essential oil of the roots of C. longa L. and to provide optimal conditions for its analy-sis. The dried, crushed roots of C. longa L. were used as raw materials (country of origin - Uganda). Methoxynonafluorobu-tane...

Aim of this study is validation of quantitative determination methods for Fexofenadine hydrochloride, Cyanocobalamine in separate ophthalmological dosage forms using UV-spectrophotometry instrumentation. Assay tests of the studied ophthalmological dosage forms were carried out using the APIs and reagents...

Early blight (Alternaria solani) is a potential disease of tomato that reduces its production globally both in conventional and tunnel cultivations. Due to variability in pathogenic isolates, prolonged active disease cycle phase and broad host range early blight is very difficult to manage. 8 microorganisms...

Wheat germ - a product of deep processing of wheat grain is a native plant component with high nutritional and biological value. Due to the valuable biochemical composition and high functional and technological properties of the wheat germ, it has significant prospects for use in food, confectionery,...

Bacteria capable of degradation of a number of toxic organic compounds (aromatic hydrocarbons, n-alkanes, phenol and its chlorinated derivatives) were isolated from the rhizosphere of plants growing on “clean” and oil-contaminated soil. The most active strain, Lysinibacillus sp. Fg1 was able to utilize...

The aim of the work was to diagnose diseases through autopsy and additional examinations and to determine the mortality structure and statistics in pigs of fattening groups on pig farms of industrial type. The objects of the study were 626 pigs from 15 pig «farrow-to-finish» farms in a number of regions...

The work describes the procedures used to isolate microorganisms and the initial determination of Shewanella sp. from the Vezjolka River, Belgorod Region of Russia. The isolates obtained during isolation are characterized by signs corresponding to those declared by the authors of the recipe for selective...

This paper considers the possibility of intensification of biochemical processes, stabilization of biotechnological properties of semi-finished bakery products, in particular, liquid rye leaven and reduction of the production cycle by the introduction of biogenic plant raw materials, composition of herbal...

The root cause of premature culling of animals from the herd as a result of diseases and injuries is a lesion of distal portions of limbs of an infectious etiology, which include Mortellaro’s disease. Mortellaro's disease affects up to 60 percent of the cattle in Russia. BelNano was developed, consisting...

The article is devoted to the study of indicators of the cardiorespiratory system in rats of different sexes under conditions of chronic hypokinetic stress (HK), on the background of normal nutrition, and also in conditions of long-term restricted nutrition (RN). It was shown that the 21-day exposure...

Modern nutrition science focuses on the creation of innovative technologies and increase the assortment of finished products with directional changes in chemical composition and properties with a view to implementation in the food industry. The problem of imbalance of PUFA in a diet of people is investigated....

The aim of the work is to develop classification and systematics of Medical Clays. Tasks: to conduct screening marketing study of the pharmaceutical market of medical clays in Russia and neighboring countries; to develop classification and systematics of Medical Clays with their characteristics. The...

The current policy of forming the collection fund of the laboratory of ornamental plants of the MBG RAS is aimed at creating not only large, but also unique collections that can be in demand in various aspects of research work. Thus one of the most actual and obvious basic directions of use of resources...

Aim of this study is the theoretical justification and experimental confirmation of new approach to description of equilibrium state in extraction system vegetal raw material-extractant. In framework of this study the milled raw material was used containing the particles sized 0,1-0,5 mm: roots and rhyzomes...

The purpose of this work is an experimental study of the extraction properties of Novec 1230 perfluoro organic solvent in regards to various types of low-polar biologically active substances from plant materials. For the study purposes, we used the following ground plant raw materials with particle size...

The aim of this study was to develop the effect of substance Z–109 - a bicyclononan derivative, presumably belonging to the class of ampakines on the memory of rats undergoing cerebral ischemia. The evaluation of mnestic functions was carried out on the model of the conditioned passive avoidance reflex....

Developed pharmaceutical composition based on two innovative chitosan-containing substances: the chitosan-chymopsin complex and the chitosan-miramistin complex, for the treatment of infected wounds in gel dosage form for external use has four types of pharmacological effects - necrolytic, antimicrobial,...

New Russian F1 “Rubinovaya” cultivar of Daucus carota was found to be pink-colored due to biosynthesis of lycopene and β-carotene in relatively high overall level (up to 0.200 mg per 1 g of fresh weight, FW). The typical carotenoid composition of carrot roots with pink color were determined by proposed...

As a result of hybridization of species: Prunus domestica L., Prunus salicina Lindl., Prunus rossica Erem., Prunus brigantina Vill., Prunus persica (L.) Batsch., Prunus armeniaca Lin., Prunus pumila L., Prunus spinosa L. crossed between Interspecific hybrids combining genomes of 2 or more species ((Prunus...

During the drugs production, one of the most important requirements of good manufacturing practice (GMP) is the equipment cleaning from active pharmaceutical substance residues, which has to be carried out to prevent cross-contamination in case of switching from the production of one drug to another....

scientific work is devoted to the study of the biological activity spacerized complex bis(2-Pyridyl) -3- (1,2,4-Triazolyl) Propane And 11-Hydroxy-1,1-Ethylidenediphosphonic Acid in the dose range from 5 to 200 mg / kg. The results of the study of acute toxicity showed that spacering of the HDA+BTP complex...

The article presents the developed methodological approach to the technology of conducting a multi-aspect examination of the range of pharmaceutical products. This approach may be of interest for optimizing the prescription of pharmaceutical products by doctors in medical organizations during the pharmacotherapy...

Anthocyanins of red colored leaves of Cercis canadensis L. were found to be 3-glucosides of five common anthocyanidins - of delphinidin, cyaniding, petunidin, peonidin and malvidin with overall accumulation more than 350 mg per 100 g of FW in early summer. The content of anthocyanins gradually drops...

Levels of strontium-90, cesium-137, thorium-232, potassium-40, and radium-226 were studied in medicinal plant species, along with the accumulation of these elements from soils. Medicinal plant raw materials from ten plant species were collected in 36 sampling points in the Voronezh Region. Findings...

The aim of this work is phytochemical studies and standardization of Scabiosa succisa L. By reverse phase high performance liquid chromatography of ethanol extract substances belonging to polyphenolic compounds were found, among which hydroxycinnamic acids predominate. Chlorogenic acid and flavonoid...

The significant importance for preventive measures of early disability of patients with diabetes belongs to drug treatment of underlying and concomitant disease, that must be provided by high –value medicines timely and in full volume. In this regard, it is important to find ways to improve the quality...

In this work we bring the results of the new Timiryazevskaya 42 triticale cultivar potential productivity analysis at different amount of nitrogen fertilizer application. Field experiments held in between 2016 and 2018 on podzol soil showed that increase of fertilizer dose led to the increased yield...

The need for a systematic phytochemical studying of Nepeta cataria L. is related to solving the problem of using of this valuable plant resource. The purpose of the work was to study the dynamics of the accumulation of biologically active substances in the aboveground phytomass of N. cataria L. in the...

The results of the experiments connected with the study of the allelopathic effect of marigolds daily water infusion on the mustard seeds swelling in combination with the different concentrations of infusion, different temperatures and acidity of the medium are presented. The complex dependence of water...

The article deals with studies of the mutual influence of the components of herbs. The research in this area is too difficult because of the lack of an accurate data about chemical composition of natural raw materials. Therefore, the aim of the research was: to study the aspects of chemical composition...

The technology of anaerobic fermentation of organic substrates and especially of organic wastes with rich microbiota needs effective method to observe the microbial community on the different stages of substrate transformation, including its digestion, fermentation and conversion of its products to methane....

A market economy characterized by existing of uncertainty and the possibility of choosing one or more development directions for the pharmaceutical market subjects causes risk situations. The reasons for their occurrence are usually the company affiliation, its size, form of ownership, legal status,...

The aim of the work was to establish the level of steroid hormones in the blood serum of deep-pregnant cows and calves obtained from them and to establish correlations between hormonal and immunological parameters of the mothers and newborns. It was found that steroid hormones of the mother and the fetus...

The article discusses the technology of obtaining phytosubstances using modern methods of extraction of medicinal plant materials: ultrasonic extraction, two-phase extraction. On the example of various types of plant materials, a comparative analysis was carried out and the advantages and disadvantages...

Bacteria of the genus Propionibacteruim are the microorganisms with great biotechnological potential. The article deals with studies of biological properties of new propionic acid bacteria strains isolated from raw milk in different regions of Republic of North Ossetia-Alania. According to morphological...

Building a unified educational space allows students to choose and build their own career. In connection with the adoption of the Bologna system there was a modernization of the education system in Russian Universities. The article highlights the features of the development, formation and construction...

The analysis of the inhibiting effect of antibiotic from the cephalosporin series, nanoencapsulated gellan and xanthan gum in comparison with native antibiotics was performed. Differences in the effect of drugs depending on concentration were studied as well as positive effect of prolongation of activity...

The role of the PIC/S organization in the pharmaceutical industry was noted, the main aspects and place of inspection activities in the production of medicines were determined, the general classification of incompliances, as well as the main methods and tools for risk assessment were considered. An object...

Therapeutic sulphide silt mud from Tambukan lake has been formed for a long period of time. Balneological value of silt mud from that specific lake is high because of high level of ferrous sulphides and water-soluble salts in it’s content, including recognized as therapeutically active bromine and boric...

This article regards the problem topicality of goods traceability which State Veterinary Supervision controls within the territory of Russian Federation, this article regards the advantages of issuance electronic veterinary certificates by the Federal State Information System «Mercury». This article...

Reaction of sugar beet seedlings to treatment of seeds with the chemical Zeroks® (high-colloidal solution) has been studied. The contact bactericide and fungicide Zeroks® (high-colloidal solution) in which silver nanoparticles are its active factor has been used to test growth regulation properties....

The article presents the results of the usage efficiency of broilers of non-conventional raw materials of vegetable dry beet pulp, which has a positive impact on the physiological characteristics of poultry and quality indicators of meat. The research was carried out at the premises of the educational...

The results of selection work for restoring the varietal qualities of Strigunovsky local varieties of bulb onion. 7 promising lines of onions with stable varietal qualities, such as the shape and color of the bulbs, the yield of bulbs and seed productivity were obtained.

The automatic adaptive feeder for fish feeding in recirculation plants has been developed and tested. It was found that the use of this feeder allowed to increase the yield of fry per 1 m³ by 35% and 13.6%; the yield of fingerling – by 45.9% and 18.5%; in the final period of cultivation – by 52.3% and...

A method has been developed for obtaining samples of a derivative of 1,4-dihydropyridine-nifedipine gels using the solid dispersion technique. A quality assessment of the obtained soft dosage forms has been performed. The effectiveness of the proposed technique for obtaining nifedipine gels has been...

The research paper includes the information on the application of nanostructured motherwort extract in the production of fruit jelly candy, which can be used as a therapeutic functional food product. The size of nanostructured motherwort extract was determined by a nanoparticle tracking analysis (NTA)....

The effect of antibiotics and vitamin-mineral supplements on Saccharomyces cerevisiae strains CNCM I-1077 (feed additive Lewisel SC Titan Plus for cattle, horses, goats, and sheep) and CNCM I-1079 (feed additive Lewisel SB Titan Plus for poultry, pigs) studied. The yeast contained in the feed additive...

The publication discusses new data about chemistry and application of thiourea dioxide and its sulfur-containing relatives.

The work was performed in 2019 at the Department of Food Technology of Saratov State Agrarian University named after N.I. Vavilov and at the Research Agricultural Institute. Using the Mixolab instrument, the basic parameters of the rheological state of the dough from patent wheat flour, flour from seeds...

The aim of this work was to study the mechanisms of action and determine the effectiveness of the use of probiotic fodder additives «Amilocin» in the production of food eggs. In the course of the experiments, we found that the introduction of «Amilocin» supplement with water to laying hens of the cross...

In this paper, we studied the antimicrobial activity of callus tissue Salvia pratensis L. obtained in vitro against Escherichia coli and Staphylococcus aureus. The most effective sterilizing agents for disinfection of plant explants with their introduction into in vitro culture were selected. The composition...

In this study, plant extracts of Artemisia absinthium L. were produced. Herbal extracts from leaves and flowers were evaluated for antibacterial activity against Escherichia coli and Staphylococcus aureus. As a result, it was found that plant extracts from Artemisia asbinthium flowers have the greatest...

The technology of obtaining a powdered semi-finished product from Pleurotus ostreatus is proposed. Assessment of the quality of the semi-finished product was made according to the organoleptic and physico-chemical indicators. Found that the share of nitrogen of soluble substances, including non-protein...

The purpose of the study is development technology of receiving mineral waters with nanoparticles of selenium and studying of their stability. The studied samples — the concentrated solution of nanoparticles of selenium contens selenium about 1,4 mg/ml, mineral water of the Krasnoarmeysky source. The...

Soil microbial communities perform a number of important functions ensuring fertility. They depend on physical and chemical composition of soil and applied agricultural technology. To control the state of the soil, it is necessary to use methods that allow to quickly assess the dynamics of the structure...

The supramolecular complex formation in aqueous solution between fatty acids (with the content of α-eleostearic acid more than 70%) and β-cyclodextrin, βCD, was supported by FT-IR and UV spectroscopies as well as by XRD-analysis. RP HPLC was utilized for investigation of the content of fatty acid in...

Buttermilk is a by-product obtained during butter preparation, has a nutritional composition similar to skimmed milk but with an increased proportion of phospholipids. Phospholipids was proved to have functional properties. Buttermilk is produced in large amounts due the preparation of butter and could...

Authentication of Syringa varieties is required in all major collections. The initial information left by the originators does not make it possible to uniquely identify the varietal affiliation of the samples. In most existing descriptions of varieties, even detailed ones, subjective categories are largely...

Two cultivars of purple carrot ‘Pupur’ and ‘Mayami shokoladnaya” were investigated. Anthocyanins of both cultivars was qualitatively the same – main compound was cyanidin-3-feruloylhexosyl-pentosyl-hexodide, mole fraction of the anthocyanin was approximately 72 % of the overall anthocyanin content of...

An important problem of cattle breeding in Russia is the creation of a solid fodder base. Due to its absence, the genetic potential of dairy and beef cattle in our country is realized only by 30-50%. This work is devoted to the study of the influence of the belotine feed additive on the productivity...

In birds, acute stress (a three-day 12-hour inversion of the photomode) is associated with the dominant activity of the sympathetic hypothalamus and hippocampus, which suppress the tone of the parasympathetic section and the reticular formation of the midbrain. The effect of hyperglycemia on the background...

The aim of this study was to study the reserves of increasing the productivity of pigs by introducing the feed additive "Elevit" into their ration during the growing period from 1 to 3 months. The studies were conducted on the Collective Farm named after Gorin of the Belgorod district of the Belgorod...

Currently, there is an increasing interest in exopolysaccharides as effective biocorrector and auxiliary technological agents. Experimental studies were carried out to obtain fermented milk ice cream with a high content of exopolysaccharides. As a nutrient substrate for the cultivation of probiotic microorganisms,...

this paper presents the results of a study and modeling of the influence of the solvent’s dielectric constant on the extraction of eugenol from the Laurus nobilis L leaves. The aim of this work is to study the effect of the solvent on the extraction of eugenol from the leaves of Laurus nobilis L., to...

animal studies with laser Doppler flowmetry showed, that there were local and systemic changes in the microcirculation caused by hypokinetic stress, what allowed us to expand our understanding of the pathophysiological processes caused by the influence of a stressing factor on the body. A study of the...

The nutraceutical aspect of the design of new food products involves the consistent implementation of the design algorithm for multicomponent biocorrector. The analysis of potential natural sources of biologically active substances allows to prioritize products of deep biotechnological processing of...

In the recent years there is a growing demand for plant origin antioxidants, due to their potential therapeutic value and low level of side effects. Among the plant origin substances, the metabolites with antioxidant activity are the widely used which are mainly belong to the phenolic group of compounds...

The article presents the results of breeding in the department of remote hybridization of the Main Botanical Garden n.a. N.V. Tsitsin (MBG RAS) from 1946 to 2019. The aim of this work is to create high-yielding varieties of spring wheat of an intensive type that most fully meet the peculiar conditions...

The present article describes the results of the transcranial electrostimulation (TES) for the correction of blood pressure (BP) in dogs. During the experiment, systolic blood pressure (BPs), diastolic blood pressure (BPd), pulse pressure (PP), and mean blood pressure (MBP) were registered. It was established...