Study and Modeling the Influence of a Solvent on Extraction of Eugenol from Laurus Nobilis L. Leaves

DOI

10.2991/isils-19.2019.62How to use a DOI?

Keywords

Laurus nobilis L. leaves, solvents, HPLC analysis, dielectric constant, eugenol.

Abstract

this paper presents the results of a study and modeling of the influence of the solvent’s dielectric constant on the extraction of eugenol from the Laurus nobilis L leaves. The aim of this work is to study the effect of the solvent on the extraction of eugenol from the leaves of Laurus nobilis L., to propose a theoretical model for describing the results. Shredded plant material of Laurus nobilis L. leaves 0.1-0.5 mm. Aqueous solutions of ethanol (23, 39, 55, 73, 80, 96±1% v/v). The extracts were obtained by a ratio of plant materials - extractant 1:5 (w/v), insisting for 24 hours at a temperature of 24±1°C. Analysis of the extracts was carried out using reverse phase high performance liquid chromatography and a standard sample of eugenol. The dependence of the concentration of eugenol in alcohol-water extracts on the concentration of ethanol in solution was studied. It was found that the maximum concentration of eugenol is observed in solutions with ethanol concentrations of 85±15 % vol. This range of ethanol concentrations corresponds to a dielectric constant of the solvent of 33.5±3.5 units. The regression equation of the dependence of the concentration of eugenol in the extract on the dielectric constant of alcohol-water solutions is obtained. It was found that the dielectric constant of the solvent has the most significant effect on the process of isolating the phytocomponent from plant materials. A mathematical model is theoretically grounded and tested to describe the dependence of the concentration of eugenol on the dielectric constant of water-ethanol solutions. The optimal range of solvent dielectric constant was found to achieve the maximum concentration of eugenol in the extract.

Copyright

© 2019, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Valentina Radyukova
AU  - Nikolay Boyko
AU  - Elena Zhilyakova
AU  - Zoja Tsvetkova
AU  - Diana Martceva
AU  - Anastasia Malyutina
AU  - Valentina Kasakova
AU  - Daria Fadeeva
AU  - Ghadeer Balloul
PY  - 2019/11
DA  - 2019/11
TI  - Study and Modeling the Influence of a Solvent on Extraction of Eugenol from Laurus Nobilis L. Leaves
BT  - Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)
PB  - Atlantis Press
SP  - 356
EP  - 359
SN  - 2468-5747
UR  - https://doi.org/10.2991/isils-19.2019.62
DO  - 10.2991/isils-19.2019.62
ID  - Radyukova2019/11
ER  -