eFood

As the supply chain of food around the world has become more and more globalized and complicated, food safety issue has attracted considerable concern owing to the widespread pollution of the whole ecosystem and the extent of their impact on the well-being of human beings. Correspondingly, a variety...

Diabetes mellitus is a metabolic disease with a high mortality rate worldwide. MicroRNAs (miRNAs), and other small noncoding RNAs, serve as endogenous gene regulators through binding to specific sequences in RNA and modifying gene expression toward up- or down-regulation. miRNAs have become compelling...

Living cells have several mechanisms to avoid acidic conditions created by excess protons. The protons are extruded to the extracellular space via the plasma membrane by various types of transporters such as the Na+/H+ exchanger and monocarboxylate transporters, which hereby contribute to the exclusion...

Alkylresorcinols (ARs), which are phenolic lipids found in wheat bran, have attracted a considerable amount of attention because of their antioxidant properties. However, the mechanism of ARs for regulating neuroprotective activity remains unclear. The correlation between the cellular neuroprotective...

The aphrodisiac property of Eurycoma longifolia has led to an increase in the demand for its Herbal Medicinal Products (HMPs). However, the efficiency of such HMPs depends on the usage of their genuine raw materials. The conventional methods cannot identify species in processed form. The authentication...

Propolis is a lipophilic sticky substance collected by bees that has been used by humans for centuries. Owing to its healing, antioxidant, and other medicinal properties, its chemical composition has been widely studied. Most pharmacological properties of propolis have been attributed to its phenols...

The proteomics of donkey milk from China’s major producing areas have not been well documented. To explore the protein profiles of donkey milk from China, this study preliminarily investigated caseins and whey proteins in products from two major producing areas using quantitative proteomics approach....

This study investigated the inhibitory effects of the Ethanol Extract (EE), Free Phenolic (TF), Esterified Phenolic (TE) and Insoluble-bound Phenolic (TI) from Rhus chinensis Mill. fruits on α-glucosidase, Dipeptidyl Peptidase-4 (DPP-IV), and the formation of Advanced Glycation End (AGE) products. Results...

Huntington’s disease (HD) is a neurodegenerative disorder characterized by progressive loss of neurons, which leads to behavioral systems and mental decline. HD is linked to repeat expansions of cytosine, adenine, and guanine in the Huntingtin (HTT) gene that give rise to mutation, leading to the formation...

Acetylcholinesterase (AChE) is a critical enzyme involved in nerve functions and signal transmission within the brain. However, during aging, excessive AChE activity often leads to rapid and progressive depletion of acetylcholine (ACh), the major neurotransmitter. Shortage of ACh leads to reduced neurotransmission...

More than 50% of the world’s population is infected with Helicobacter pylori. H. pylori is the major causative agent of gastric ulcers and gastric cancer. H. pylori eradication using antibiotics either alone or together with a proton pump inhibitor is the primary strategy to decrease the incidence of...

Nowadays, obesity in humans is a huge challenge requiring effective, readily available, and low-risk alternative treatments. Intake of edible Non-Digestible Polysaccharides (NDPs) is regarded as a promising strategy to combat obesity. Herein, an overview of the behavior of NDPs in the Gastrointestinal...

This study investigated the effects of feeding rats for 24 months on different unsaturated fats (virgin olive, sunflower, or fish oil) on gingival mitochondrial ultrastructure and expression of genes related to mitochondrial biology as well as the amount of circulating fatty acids in the plasma. Results...

Different separated protein fractions by the electrophoretic method in polyacrylamide gel were used to classify two different types of honeys, Galician honeys and commercial honeys produced and packaged outside of Galicia. Random forest, artificial neural network, and support vector machine models were...

The combination of microwave irradiation, ultrasonication treatment, and enzyme-assisted extraction approach was applied to study the extraction efficiency and antioxidative activity of curcumin from turmeric (Curcuma longa L.) using Response Surface Optimization (RSM). The effects of the power and treatment...

Sonchus oleraceus Linn. is of great interest in scientific platform because it exhibits significant biological activities. This study investigated the liver protective effects and mechanism of phenolic extract from S. oleraceus (SOL) on Streptozotocin (STZ)-induced diabetic rats. SOL significantly increased...

The buds of Vaccinium dunalianum Wight (VD) are widely used in Yunnan as herbal tea [Que Zui Tea (QT)] and herb. However, the security and toxicity of QT have not been determined yet. The aim of this study is to evaluate the acute and subacute-toxicity of hot water (QTW) and aqueous-ethanol (QTE) extracts...

The aim of this study was to investigate and compare the change in the total content of phenolic compounds, flavonoids, and the antioxidant capacity in Manuka Honey (MH) after gastrointestinal digestion and different purification methods. MH was subjected to an in vitro gastrointestinal simulation process,...

We evaluated dendrobine for its potential effect on Inflammatory Bowel Disease (IBD) progression using the intestinal epithelial Caco-2/RAW264.7 macrophage co-culture cell model. The results showed that dendrobine maintained the tight junction (TJ) proteins in co-cultured Caco-2 cells, suggesting its...

The whole plant of Plantago depressa is commonly used as traditional Chinese medicine and functional food ingredient. Total phenolic content and total flavonoid content evaluation indicated that its ethyl acetate and n-butanol fractions were rich in polyphenols. However, to date, the polyphenolic profile...

Society’s latest lifestyle has developed to a more rapid mobilization and advanced technology which makes people’s daily needs of nutrients have altered as well. This phenomenon comes to consequences where healthy diet has been neglected and people consume food only to fulfill the calories—which can...

Natural polyphenols have been reported much attention in recent years for their hypoglycemic actions and diabetes-related pathologies. Free and simple polyphenols can be digested and absorbed in the small intestine, while complex polyphenols are utilized by intestinal flora in the large intestine. Microbial...

Health consciousness and the need to maintain immune system have increased the demand for fresh fruit and vegetable juices due to the presence of nutritional benefits including colorful pigments such as chlorophylls, carotenoids, and anthocyanins. Besides providing green, yellow, and red color in fruits...

Laccase is a Class 1 oxidoreductase enzyme, which catalyzes the oxidation of a wide range of phenolic substrates. Previously, several reviews had highlighted on the industrial importance of laccase, including in food industry. Similarly, the ability of laccase to crosslink and polymerize food protein...

Due to the misuse of pathogen-infected food, human beings continue to face serious diseases and even deaths. Thus, researchers from all walks of life concern on prevention, detection, and resistance for pathogenic bacteria. It is necessary to develop and explore a fast, cost-effective, portable, and...

The consumption of exotic fruits is rapidly increasing in European countries. Some of these products have attracted much interest due to their alleged properties of preventing malnutrition, over-nutrition, and disease, maintaining a healthy body. Scientific studies on these fruits are multiplying, including...

Antioxidant activity is one of the most studied properties of coffee as a beverage, and is mainly ascribed to its polyphenol content, although there is limited scientific literature regarding its mechanism of action at the molecular level. In recent years, epigenetics has been featured as a promising...

In this study, ultrasound (US) and nisin, applied individually or in combination (US + nisin), were investigated to determine their inactivation effect on Staphylococcus aureus in nutrient broth (NB) and milk. The inactivation of S. aureus by nisin at 0, 25 and 37°C followed “fast to slow” two-stage...

Geranium wilfordii Maxim is a commonly used traditional medicine and as decoction pieces in drinks for treating acute and chronic rheumatalgia. Earlier research showed it could inhibit xanthine oxidase and had a strong antioxidative activity. In this study, four compounds namely, corilagin, geraniin,...

The analysis of lactoferrin separation will be an important application in prospect. To develop a new strategy for the detection of lactoferrin, this work adopted the method of uncoated Capillary Electrophoresis (CE), through optimizing the parameters of background electrolyte, pH, surfactant, buffers...

The search for novel natural ingredients has been stimulated by the food and non-food industries, and roots of Pachyrhizus erosus (jicama) emerges as promising crops for industrial production due to its crispy and succulent flesh and high yield. Therefore, jicama starches from Fujian Province (SFJ) and...

The aim of this study was to examine the antioxidant capacity of Trypsin-hydrolyzed corn silk proteins, specifically radical scavenging, ferric reducing and anti-lipid peroxidation activities, as well as stability after heating and simulated gastrointestinal digestion. Among the 1–5-h hydrolysates, the...

A facile method for the synthesis of molecularly imprinted polymers (MIPs) onto CdTe quantum dots (CdTe-QDs@MIPs) was successfully developed, and for the first time used as a sensitive fluorescent nanosensor for specific and rapid determination of caffeic acid (CA) in apple juices. Sol–gel polymerization...

The combination of Near-Infrared Spectroscopy (NIR) and Raman Spectroscopy (RS) of 100 honey samples collected from different countries were used to develop the calibration model for determination of single phenolic compound. In high-performance liquid chromatography with diode-array detection analysis,...

γ-Aminobutyric Acid (GABA) is a secondary metabolite produced in Monascus-fermented food. The mycotoxin (citrinin), another major secondary metabolite, is neurotoxic to humans and thus it diminishes the social acceptability of Monascus-Fermented Rice (MFR). The study was aimed to enrich GABA content...

Dihydromyricetin (DHM) dramatically improved the quality of life for Streptozotocin (STZ)-induced diabetic rats and significantly increased the activity of antioxidant enzymes in the liver. Moreover, DHM successfully ameliorated diabetes-induced liver damage by suppression of apoptosis in the liver,...

Traditional medicine which is based on the observations of the patient’s condition after administration of herbal remedies describes a vast number of plant species with potential application in Tuberculosis (TB) treatment. However, only a small number of plant derived secondary metabolites were shown...

Osteoporosis is a degenerative bone disease affecting millions, mostly the aging population. Osteoblasts and osteoclasts maintain the balance in bone resorption and formation. Changes occurring in the differentiation, proliferation and activity of these two cell types result in lower bone mass and microarchitecture...

The annual global mortality rate of cancer has increased dramatically. Although various therapies are used for cancer, the results have not been satisfactory. Chemotherapy is currently the most common treatment option. However, serious side effects and drug resistance impede the therapeutic efficacy...

Garlic (Allium sativum L.) has been not only consumed as flavor vegetable, but also recorded as a prophylactic and therapeutic medicinal plant since ancient time. Its characteristic pungent flavor limited its application in food product development. Black garlic made from garlic by a thermal processing...

Brine shrimp is a genus of aquatic crustacean, and is considered a dietary carotenoid resource by local residents from eastern China. In the present study, harvested brine shrimp were fed with the dried powders of tomato fruit (Solanum lycopersicum, as a lycopene source), marigold flower (Tagetes erecta...

Pig blood is an important by-product of the meat industry, which has not been fully utilized. In this study, Pig Blood Cells (PBC) were hydrolyzed by Alcalase and followed with simulated Gastrointestinal (GI) digestion to generate bioactive peptides. The antioxidant properties and the intestinal epithelial...

Advanced Glycation End Products (AGEs) could be formed with α-dicarbonyl compounds as intermediates; however, simultaneous determination of AGES as well as their precursors and intermediates have rarely been mentioned, so as to investigate the reaction. In this work, lysine was reacted with aldoses (galactose,...

The gut microbiota—the community of microorganisms in the gut—has been implicated in many physical and mental disorders in addition to intestinal diseases. Diets are the most studied and promising factors for altering it. Indeed, certain dietary interventions that increase fiber intake rapidly change...

The Cerrado is the second largest vegetation formation in Brazil, after the Amazon, and is the richest tropical savanna in the world in terms of biodiversity. This study aimed to evaluate cagaita fruits for bioactive compounds and nutrients during their physiological development. The fruits were assessed...

Osteoporosis is a disordered metabolic disease occurred congenitally or secondary. Although peptide agents have been approved to prevent osteoporosis administrated through subcutaneous injection, rare reports focused on peptide oral administration for preventive purpose. An eight peptide, P-CG-01 (YRGDVVPK)...

Diabetes mellitus is associated with several complications, which may result from one or more factors including increased flux of polyol pathway. This study evaluated the inhibitory potential of four citrus fruits namely Citrus paradisi Macfad. (grape), Citrus limon (L.) Osbeck (lemon), Citrus aurantifolia...

The investigation of indigenous wine yeast can facilitate the production of distinctive Beijing wine by providing wineries with more choices in distinctive wine yeasts. Wine yeasts that were isolated from grape must during spontaneous fermentation and from vineyard soil were preliminarily classified...

Walnut proteins and peptides have been reported to have great zinc-carrying activity. In this study, the decapeptide EPNGLLLPQY (WP-10) derived from walnut protein has been prepared to figure out zinc binding mechanisms and structure–activity relationships. The space-conformation of this peptide has...

The purpose of this descriptive cross-sectional survey study was to assess the hygiene and safety precautions implemented by street food vendors in the Urban district of Zanzibar. The study involved 265 food vendors with immobile food vending sites. An organized researcher-executed questionnaire developed...

Anthocyanins are one of the most important water-soluble pigments in the nature. Interests in the research of anthocyanins are increasing due to its nutritional value and biological activity. Extraction, separation and qualitative and quantitative analysis of anthocyanins are indispensable and important...

Coronavirus disease 2019 (COVID-19) is an infectious fatal disease caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) with millions of individuals infected globally within few months of its outbreak. During infection, the SARS-CoV-2 main protease binds directly to Angiotensin-converting...

Coronavirus Disease 2019 (COVID-19), an infectious disease caused by SARS-CoV-2, has become the most contagious pandemic in the world. The binding of SARS-CoV-2 spike glycoprotein Receptor-binding Domain (RBD) to human angiotensin-converting enzyme 2 receptor precedes cell entry. Thus, RBD of SARS-CoV-2...

Actinobacillus pleuropneumoniae (A. pleuropneumoniae) and Haemophilus parasuis (H. parasuis) are important pathogens of swine, which cause great economic losses in the swine industry and bring great safety hazards to food safety. In this study, we established a duplex Droplet Digital Polymerase Chain...

The Refined, Bleached and Deodorized (RBD) Coconut Oil (CO) and RBD Palm Oil (PO) are heavily consumed as cooking oils by Asians. Recently, Virgin Coconut Oil (VCO) and Palm-pressed Mesocarp Oil (PPMO) emerged into the market as functional oils. A number of studies were conducted to extract these edible...

As quaternary benzo[c]phenanthridine alkaloids, sanguinarine and chelerythrine possess multiple biological activities including anti-inflammatory effects. They have been confirmed to regulate gene expression of inflammatory-related cytokines at transcription level. This work aims to investigate the glucocorticoid-like...

Glucosidase is one of the most important hydrolases in the carbohydrate metabolism pathway in human body. It is noteworthy that glucosidase was raising high attention in numerous researches, attributed to its functional values and biological activities. The expression, secretion, extraction, purification,...