All of the articles in this proceedings volume have been presented at the 2nd Lawang Sewu International Symposium 2023 on Health Sciences: Medical Laboratory Technology during December 04, 2023 in Universitas Muhammadiyah Semarang, Semarang City, Indonesia. These articles have been peer reviewed by the...

Protease enzymes in the health sector are very important, especially as anticoagulant, antithrombotic agents, as diagnostic tools and plasmin standards. It is not surprising that the need for protease enzymes in the world is very high, including in Indonesia. The supply of protease in Indonesia still...

Hemoglobin electrophoresis is the gold standard for thalassemia carriers screening. Hemoglobin electrophoresis sees an increase in HbA2, where thalassemia patients experience abnormalities in the composition of HbA2. The Mentzer index is a discrimination index formula with good sensitivity, specificity,...

Thrombosis is one of the risk factors for cardiovascular disease (CVD) that can cause death, and CVD is the leading cause of death in the world. Bacterial proteases have potential as antithrombosis agents that can be developed into CVD drugs. Indonesia’s high marine biodiversity has been recognized worldwide,...

Typhoid fever is an infectious disease, the main cause of typhoid fever is Salmonella typhi. S. typhi bacteria have characteristics such as being rod-shaped, Gram negative, motile, able to ferment lactose quickly, and are facultative anaerobes. The entry of S. typhi bacteria into the body can be influenced...

Listeria monocytogenes is a pathogenic bacterium, which prevalence in the aquatic ecosystem and seafood products become a major threat to public health. Several virulence genes had been targeted for the PCR (polymerase chain reaction) detection of L.monocytogenes including hly coding for listeriolysin...

This study aims to evaluate gut microbiota colonization in the first two years of a child’s life and explore the potential of the gut microbiota for the development of in vivo diagnostics (IVD) of degenerative diseases by reconstructing the dynamics of early colonization of gut microbiota at a genomic...

Malaria is caused by a parasitic infection of the genus Plasmodium. Plasmodium falciparum is the cause of almost all deaths caused by malaria. Malaria problem has been exacerbated in recent years by the development and rapid spread of P. falciparum resistance to antimalarial drugs. Resistance to antimalarial...

Pangasius (Pangasius hypophthalmus) is a source of high animal protein and a freshwater commodity that is widely cultivated in Indonesia. One of the disadvantages of pangasius as a food ingredient is that it rots easily. To avoid spoilage, the fish is preserved using wet salting. The purpose of this...

Type 2 Diabetes Mellitus (T2DM) is a chronic disease indicated by blood sugar level disorder and also influenced by genetic and environmental factors. Many diabetes patients experience dyslipidemia, which is known as diabetic dyslipidemia. In the latest research, SLC2A1 gene polymorphism is strongly...

Multidrug resistance tuberculosis (MDR-TB) is a form of tuberculosis bacterial resistance to at least two first-line anti-TB treatments, isoniazid and rifampicin, the two most effective TB medications. Treatment of Drug Resistant TB is set to be part of the national TB Control program. MDR-TB cases continue...

Comorbidity between diabetic mellitus (DM) and tuberculosis (TB) can raise the incidence of the other. Uncontrolled diabetes mellitus (plasma HbA1C level > 7.0%) and five additional risk factors were discovered to have an impact on the failure of TB treatment. This study aims to identify the relationship...

Head lice Pediculus humanus capitis are parasites that live on the scalp. Garlic and citronella are plants that can be used as natural insecticides. Allium sativum L. (garlic) contains metabolites of the flavonoid class, saponins, and allicin which have toxic properties to insects so they can be used...

Scabies is still a health problem that often occurs in boarding school environments. Several previous studies have discussed the risk factors for scabies in several boarding schools, but those discussing scabies in boarding schools in the Central Java region are still limited. This study aims to analysed...

Noise-induced hearing loss (NIHL) is hearing loss resulting from exposure to noise with a fairly loud intensity over a long period of time, usually due to noise from the work environment. Currently, NIHL is still a major problem in developed countries. Based on the National Committee for the Management...

The efficacy of Spatholobus littoralis extract for incision wound is not fully understood. Here, we report the wound healing activities of Spatholobus littoralis extracts in incision wound models in rat. The aim of the study was to measure the wound length on rat’s incision wound infected by Staphylococcus...

Indonesian people use cooking oil extensively in food processing. Free radicals created when cooking oil is repeatedly heated to high temperatures. Oxidative stress is a result of free radical formation in tissues or cells. By Malondialdehyde (MDA), the degree of oxidative stress can be determined. Antioxidants...

Systemic Lupus Erythematosus (SLE) is a systemic disease with a wide range of clinical manifestations. SLE clinical manifestations include hematological symptoms such as anemia (low hemoglobin levels) and leukopenia. Anemia in SLE occurs by suppressed erythropoiesis caused by chronic inflammation, whereas...

Monosodium glutamate (MSG) is a food additive used as a food flavoring. Excessive use of MSG can increase Reactive Oxygen Species which has an impact on rat organ damage, characterized by increased levels of malondialdehyde (MDA). Kesum leaves (Polygonum minus Huds.) contain antioxidants which can reduce...

The incision is a wound that has taken the shape of a linear tear as a result of being sliced by a sharp object. Antibiotics are required to limit bacterial development during wound healing to prevent infection. Because improper antibiotic use might lead to resistance, there are other options for wound...