Artery Research

Ageing and cardiovascular risk factors, particularly uncontrolled hypertension, adversely impact arterial stiffness and wave reflection leading to increased central systolic blood pressure. Carotid-femoral pulse wave velocity is the “gold standard” method for the assessment of aortic stiffness. Increased...

The development of non-invasive technology to perform pulse wave analysis and accurately determine central blood pressure has facilitated the study of central blood pressure as a physiologic and biomarker parameter. Central systolic blood pressure (cSBP) has been shown to be significantly associated...

Carotid-femoral (aortic) pulse wave velocity (PWV) is the modern benchmark for the assessment of arterial stiffness. Current European hypertension guidelines acknowledge the good cardiovascular (CV) predictive value, reproducibility and cost-effectiveness of PWV. Aortic PWV is an asset to classical cardiovascular...

The study of vascular adaptation to extreme conditions, and in particular to hypoxia, represents a unique opportunity in cardiovascular physiology, with relevant translational implications. First, it has crucial clinical consequences for about 140 million people worldwide living at high altitude and...

Purpose: With the advances in the new image techniques and 3D modeling, angiography computed tomography (A-CT) has became a very useful image for studying vessels. Renal artery (RA) variations are common, and have a clinical relevance in pre-operative planning. There are several descriptive studies made...

Measures of arterial aging have the potential to improve risk prediction beyond traditional risk scores. Such biomarkers that fulfil most, or some of the strict criteria of a surrogate end-point are aortic stiffness (IIa level of recommendation in European Guidelines and Position Papers) and central...

Background: The mechanisms linking ABO blood group to coronary atherosclerosis is inconsistent and not fully understood. Objectives: To investigate the relationship between ABO blood groups with coronary atherosclerotic markers (coronary artery calcification (CAC), coronary plaque presence and coronary...

Competent elastic fibers endow central arteries with the compliance and resilience that are fundamental to their primary mechanical function in vertebrates. That is, by enabling elastic energy to be stored in the arterial wall during systole and then to be used to work on the blood during diastole, elastic...