Artery Research

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Volume 14, Issue C, June 2016, Pages 36 - 40

ABO blood group differences relationship with coronary atherosclerotic markers

Authors
Hussein Nafakhia, *, Hasan A. Al-Nafakhb, Abdulameer A. Al-Mosawib
aInternal Medicine Department, AL-Sader Teaching Hospital, Medicine College, Kufa University, Najaf, Iraq
bRadiology Department, Medicine College, Kufa University, Najaf, Iraq
*Corresponding author. Internal Medicine Department, Medicine College, Kufa University P.O. 21, Kufa, Najaf, Iraq. Tel.: +964 78 218 41 16; fax: +964 34 09 52. E-mail address: husseinaf.alnaffakh@uokufa.edu.iq (H. Nafakhi).
Corresponding Author
Hussein Nafakhi
Received 9 February 2016, Accepted 9 March 2016, Available Online 2 April 2016.
DOI
10.1016/j.artres.2016.03.001How to use a DOI?
Keywords
ABO blood; Coronary calcification; Pericardial fat; MDCT
Abstract

Background: The mechanisms linking ABO blood group to coronary atherosclerosis is inconsistent and not fully understood.

Objectives: To investigate the relationship between ABO blood groups with coronary atherosclerotic markers (coronary artery calcification (CAC), coronary plaque presence and coronary luminal stenosis (CAD)) and pericardial fat volume (PFV) in patients with suspected coronary artery disease assessed by Multidetector CT angiography (MDCT).

Patients and methods: Two hundred twenty consecutive patients who underwent 64-slice MDCT angiography for assessment of coronary artery disease were recruited. Of these, 180 patients (97 females (54%) and 83 males (46%) with a mean age of 51.7 ± 12 years) were found to be eligible and were enrolled in the study.

Results: We classified the blood groups into O blood group (51.6%) and non O blood group (38%). There were no significant differences in the distribution of CAC, CAD, PFV and coronary plaque presence between different blood groups (P > 0.05). The distribution of major cardiovascular risk factors did not differ significantly among the ABO blood groups, except for a significant association between O blood group and smoking (P = 0.04).

Adjustment for age and sex showed no significant associations between blood groups with coronary atherosclerotic markers or PFV (P > 0.05). Non O blood group were significantly correlated with CAC (P = 0.01), coronary plaque (P = 0.04) and PFV (P = 0.03) after adjustment for CAD and CAC.

Conclusion: No significant relationship were observed between ABO blood groups with coronary atherosclerotic markers and PFV. Non O blood group showed a significant correlation with CAC and PFV after adjustment for CAC and CAD.

Copyright
© 2016 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

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<Previous Article In Issue
Next Article In Issue>
Journal
Artery Research
Volume-Issue
14 - C
Pages
36 - 40
Publication Date
2016/04/02
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2016.03.001How to use a DOI?
Copyright
© 2016 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Hussein Nafakhi
AU  - Hasan A. Al-Nafakh
AU  - Abdulameer A. Al-Mosawi
PY  - 2016
DA  - 2016/04/02
TI  - ABO blood group differences relationship with coronary atherosclerotic markers
JO  - Artery Research
SP  - 36
EP  - 40
VL  - 14
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2016.03.001
DO  - 10.1016/j.artres.2016.03.001
ID  - Nafakhi2016
ER  -