Artery Research

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Volume 14, Issue C, June 2016, Pages 10 - 14

Arterial stiffness: From surrogate marker to therapeutic target☆

Authors
Luc Van Bortel*
Heymans Institute of Pharmacology, Ghent University, Ghent, Belgium
☆

This article was presented as lecture during the symposium on “Arterial stiffness: a translational approach” at the ARTERY 14 Congress in Maastricht, the Netherlands (October 9–11, 2014).

*Heymans Institute of Pharmacology, Ghent University, De Pintelaan 185, 9000 Ghent, Belgium. Tel.: +32 9 332 5800. E-mail address: luc.vanbortel@ugent.be.
Corresponding Author
Luc Van Bortel
Received 4 November 2015, Revised 25 January 2016, Accepted 27 January 2016, Available Online 22 February 2016.
DOI
10.1016/j.artres.2016.01.001How to use a DOI?
Keywords
Pulse wave velocity; Arterial stiffness; Target organ damage; Hypertension guidelines
Abstract

Carotid-femoral (aortic) pulse wave velocity (PWV) is the modern benchmark for the assessment of arterial stiffness. Current European hypertension guidelines acknowledge the good cardiovascular (CV) predictive value, reproducibility and cost-effectiveness of PWV. Aortic PWV is an asset to classical cardiovascular risk scores and can reclassify patients. Reference values for carotid-femoral PWV have been established. Together with standardisation of user procedures and patient conditions, these reference values are needed for an appropriate use of aortic stiffness in daily clinical practice. Finally, the existing evidence for a decrease in CV risk by decreasing aortic stiffness is discussed.

Copyright
© 2016 Published by Elsevier B.V. on behalf of Association for Research into Arterial Structure and Physiology.
Open Access
This is an open access article distributed under the CC BY-NC license.

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<Previous Article In Issue
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Journal
Artery Research
Volume-Issue
14 - C
Pages
10 - 14
Publication Date
2016/02/22
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2016.01.001How to use a DOI?
Copyright
© 2016 Published by Elsevier B.V. on behalf of Association for Research into Arterial Structure and Physiology.
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Luc Van Bortel
PY  - 2016
DA  - 2016/02/22
TI  - Arterial stiffness: From surrogate marker to therapeutic target☆
JO  - Artery Research
SP  - 10
EP  - 14
VL  - 14
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2016.01.001
DO  - 10.1016/j.artres.2016.01.001
ID  - VanBortel2016
ER  -