The Effect of Telang Flower Extract on the Hepatic Catalyst Enzyme of Mice Exposed to Tobacco Smoke

DOI

10.2991/978-2-38476-273-6_45How to use a DOI?

Keywords

Tobacco Smoke; Telang Flowers Extract; Catalase Enzyme

Abstract

A tobacco contains more than 4700 chemical compounds and 200 of them can be detrimental to health. These compounds include CO, CO2, HCN, NOx, nicotine, phenol, tar and cadmium which have the potential to become free radicals. Continuous exposure to chemical compounds in tobacco can result in a decrease in the body’s antioxidant levels and cause oxidative stress. Telang flower extract has antioxidant properties which can reduce the number of free radicals formed from the lipid peroxidation process. The catalase enzyme is an antioxidant enzyme used to determine antioxidant levels in mice exposed to to-bacco smoke. This research aims to analyze the effect of telang flowers extract on mice hepatic catalase enzyme that exposed to tobacco smoke. This was exper-imental research which used post-test only controlled group design. Sample of this research was 20 mice divided into 4 groups. Normale one group (N) was given standard feed, the control negative group (K0) given tobacco smoke, K1 group given tobacco smoke and telang flowers extract 2 00 mg/kgBW, and K2 group given tobacco smoke and telang flowers extract 4 00 mg/kgBW Treatment was carried out for 10 days and continued with measuring hepatic catalase en-zyme levels. Statistical tests use the one-way Anova test. All samples given to-bacco smoke responded to increased oxidation and when given telang extract was able to have a significant effect. The results of the Anava test showed significant differences between all groups. Telang flowers extract decreased hepatic catalase enzyme level of mice that were exposed cigarette smoke. So, preclinically, telang flower extract can act as an antioxidant due to exposure to tobacco smoke and reduce the risk of respiratory tract infections.

Copyright

© 2024 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Download article (PDF)

TY  - CONF
AU  - Agus Suprijono
AU  - A. W. Ariani Hesti
AU  - Endang Setyoningsih
PY  - 2024
DA  - 2024/08/02
TI  - The Effect of Telang Flower Extract on the Hepatic Catalyst Enzyme of Mice Exposed to Tobacco Smoke
BT  - Proceedings of 5th Borobudur International Symposium on Humanities and Social Science 2023
PB  - Atlantis Press
SP  - 401
EP  - 410
SN  - 2352-5398
UR  - https://doi.org/10.2991/978-2-38476-273-6_45
DO  - 10.2991/978-2-38476-273-6_45
ID  - Suprijono2024
ER  -