Proceedings of the Conference on Natural Resources And Life Sciences 2022 (NRLS-BIO 2022)

Formulation of Chewable Gummy Tablet of Moringa oleifera L. Leaf Extract Using Combination Kappa Carrageenan and Iota Carrageenan

Authors
Nabilaberty Prisma Gemilang1, Nikmatul Ikhrom Eka Jayani2, Karina Citra Rani3, *
1Faculty of Pharmacy, University of Surabaya, Surabaya, Indonesia
2Departement of Pharmaceutical Biology, University of Surabaya, Surabaya, Indonesia
3Departement of Pharmaceutics, Faculty of Pharmacy, University of Surabaya, Surabaya, Indonesia
*Corresponding author. Email: karinacitrarani@staff.ubaya.ac.id
Corresponding Author
Karina Citra Rani
Available Online 30 December 2023.
DOI
10.2991/978-94-6463-322-1_21How to use a DOI?
Keywords
Chewable gummy tablets; Moringa oleifera; Kappa Carrageenan; Iota Carrageenan
ABSTRACT

Moringa leaves were the most commonly used part of the Moringa plant because they were rich in nutrients. Moringa leaves extract was developed into a chewable gummy tablet to improve its acceptability. The main component of the chewable gummy tablet was a gelling agent. This study aims to determine the effect of gelling agent ratio (kappa-carrageenan and iota-carrageenan) on the physical characteristics of the chewable gummy tablet. Furthermore, this study was also conducted to determine the optimum formula for a chewable gummy tablet and analyze the physical stability of the prepared formula during storage. In this study, the concentration of gelling agents was 2%. The formulas were developed in this study using the various ratio of kappa-carrageenan and iota-carrageenan 1:0 (control formula), 1:1 (formula 1), 2:1 (formula 2), and 3:1 (formula 3). The results showed that the ratio of kappa-carrageenan and iota-carrageenan determined the texture, disintegration time, swelling ratio, and syneresis. The most optimum formula was Formula 1 (1:1). The characteristics of this formula were a yellow color, melon odor, sweet taste, square shape, chewy texture, the average weight was 2.86 g ± 0.02, the disintegration time was 7.47 min ± 0.02, the swelling ratio was 1.21% ± 0.20, and the syneresis percentage was 0.93 ± 0.11%. The result of physical stability evaluation during 14 days of storage also revealed that formula 1 was the most stable.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the Conference on Natural Resources And Life Sciences 2022 (NRLS-BIO 2022)
Series
Advances in Biological Sciences Research
Publication Date
30 December 2023
ISBN
978-94-6463-322-1
ISSN
2468-5747
DOI
10.2991/978-94-6463-322-1_21How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

TY  - CONF
AU  - Nabilaberty Prisma Gemilang
AU  - Nikmatul Ikhrom Eka Jayani
AU  - Karina Citra Rani
PY  - 2023
DA  - 2023/12/30
TI  - Formulation of Chewable Gummy Tablet of Moringa oleifera L. Leaf Extract Using Combination Kappa Carrageenan and Iota Carrageenan
BT  - Proceedings of the Conference on Natural Resources And Life Sciences 2022 (NRLS-BIO 2022)
PB  - Atlantis Press
SP  - 155
EP  - 164
SN  - 2468-5747
UR  - https://doi.org/10.2991/978-94-6463-322-1_21
DO  - 10.2991/978-94-6463-322-1_21
ID  - Gemilang2023
ER  -