The Relationship Between Thyroid Functions with Nutritional Status and Blood Pressure in the Women of Child Bearing Age

DOI

10.2991/ahsr.k.200215.115How to use a DOI?

Keywords

UIE, TSH, fT4, BMI

Abstract

Currently non-communicable diseases occupy the highest position in Indonesia. Hypertension and cardiovascular disease still occupy the top ten diseases. Non-communicable diseases also include thyroid dysfunction where hyperthyroidism can cause cardiovascular disorders. Patients with thyroid disease, especially hyperthyroidism, often show signs and symptoms of cardiovascular changes. On the other hand, thyroid dysfunction can cause changes in nutritional status and metabolic disorders. The incidence of hypertension is often associated by cigarette exposure. The objective of this study was to assess the relationship between thyroid function and nutritional status and blood pressure in Women of child bearing age in three areas with varying iodine status. Method. This research is Cross-sectional study on Women of child bearing age in three areas with varying degrees of iodine status, namely Yogyakarta City, Bukit Tinggi City and Purworejo districts. The sample size of each area is 160 subjects, with total subjects are 480 Women of child bearing age. Nutritional status, blood pressure, iodine salt, urinary iodine excretion (UIE), fT4 and TSH levels were measured in the subjects. History of cigarettes exposure was also collected. Analysis of variance and multivariate regression was performed to analyze the relationship between thyroid function and nutritional status and blood pressure. Results. There were significant differences between regions in the nutritional status / BMI variables, iodine salt levels, UIE, fT4 and TSH levels. Median UIE in Yogyakarta city is 220 μg/ml (more than normal), in Bukit Tinggi city is 85 μg/ml (deficiency) and median UIE in Purworejo is 225 μg/ml (more than normal). Majority of thyroid function in three areas is normal. There was a significant relationship between BMI and thyroid function (fT4) after controlling for age and a history of iodine adequacy (β = –0.132, p = 0.005). There was a significant relationship between systolic blood pressure and thyroid function (fT4) after accounting for BMI, age and a history of iodine adequacy (β = 0.117, p = 0.009). There is no relationship between diastolic blood pressure and thyroid function and there is no relationship between blood pressure with history of cigarettes exposure. Conclusion. There is a significant relationship between BMI and thyroid function and there is a significant relationship between systole blood pressure and thyroid function. Recommendation. Prevention and management of non-communicable diseases must be comprehensive because the non-communicable diseases are related to one another.

Copyright

© 2020, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Suryati Kumorowulan
AU  - DN Yusi
AU  - Ina Kusrini
AU  - DK Hastin
AU  - Ernani Budi
AU  - Nur Asiyatul Janah
PY  - 2020
DA  - 2020/02/22
TI  - The Relationship Between Thyroid Functions with Nutritional Status and Blood Pressure in the Women of Child Bearing Age
BT  - Proceedings of the 4th International Symposium on Health Research (ISHR 2019)
PB  - Atlantis Press
SP  - 590
EP  - 594
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.200215.115
DO  - 10.2991/ahsr.k.200215.115
ID  - Kumorowulan2020
ER  -