Proceedings of the International Conference on Science Technology and Social Sciences – Physics, Material and Industrial Technology (ICONSTAS-PMIT 2023)

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Unveiling the Antibiofilm Arsenal: A Mini Review on Nanoparticles’ Mechanisms and Efficacy in Biofilm Inhibition

Authors
Nurul Farhanah Yakup1, Nurul Hidayah Mohamad Nor2, Mohd Muzamir Mahat1, Rikson Siburian3, Mohd Fakharul Zaman Raja Yahya1, *
1Faculty of Applied Sciences, Universiti Teknologi MARA, Shah Alam, Selangor, Malaysia
2Low Dimensional Materials Research Centre, Faculty of Science, Universiti Malaya, Kuala Lumpur, Malaysia
3Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Medan, Indonesia
*Corresponding author. Email: fakharulzaman@uitm.edu.my
Corresponding Author
Mohd Fakharul Zaman Raja Yahya
Available Online 29 August 2024.
DOI
10.2991/978-94-6463-500-3_16How to use a DOI?
Keywords
Antibiofilm; Antimicrobial; Biofilms; Nanoparticles; Nanotechnology
Abstract

Biofilms are complex microbial communities attached to surfaces, encapsulated in a protective extracellular matrix, leading to increased antibiotic resistance, and contributing to persistent infections and widespread diseases. This mini review aims to examine the antibiofilm potential of nanoparticles (NPs) such as graphene, zinc oxide, hydroxyapatite, silicon dioxide, sodium silicate, titanium oxide, silver, gold, palladium, and tungsten. These NPs employ various mechanisms to disrupt biofilms, including sharp nanosheet attacks on cell membranes, alteration of mRNA expression, generation of reactive oxygen species that cause oxidative damage to essential biomolecules, and destabilization of the biofilm matrix. These multifaceted mechanisms underscore the potential of NPs in combating biofilms and addressing antibiotic resistance, offering promising avenues for future medical, industrial, and environmental applications.

Copyright
© 2024 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the International Conference on Science Technology and Social Sciences – Physics, Material and Industrial Technology (ICONSTAS-PMIT 2023)
Series
Advances in Engineering Research
Publication Date
29 August 2024
ISBN
978-94-6463-500-3
ISSN
2352-5401
DOI
10.2991/978-94-6463-500-3_16How to use a DOI?
Copyright
© 2024 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Nurul Farhanah Yakup
AU  - Nurul Hidayah Mohamad Nor
AU  - Mohd Muzamir Mahat
AU  - Rikson Siburian
AU  - Mohd Fakharul Zaman Raja Yahya
PY  - 2024
DA  - 2024/08/29
TI  - Unveiling the Antibiofilm Arsenal: A Mini Review on Nanoparticles’ Mechanisms and Efficacy in Biofilm Inhibition
BT  - Proceedings of the International Conference on Science Technology and Social Sciences – Physics, Material and Industrial Technology (ICONSTAS-PMIT 2023)
PB  - Atlantis Press
SP  - 177
EP  - 185
SN  - 2352-5401
UR  - https://doi.org/10.2991/978-94-6463-500-3_16
DO  - 10.2991/978-94-6463-500-3_16
ID  - Yakup2024
ER  -