Hypothesis: Relationship of skin morphology and cutaneous scarless wound healing in sunda porcupine (Hystrix javanica)

DOI

10.2991/icoh-17.2018.36How to use a DOI?

Keywords

sunda procupine, quill, hair, follicle, wound healing

Abstract

Sunda porcupine (Hystrix javanica) is one among the wild mammals of Indonesia. The porcupine skin shows peculiar appearance by the presence of quills, spine like structure, instead of hair, that commonly found in mammals. On the other hand, our previous preeliminary study observed a relatively quick process in wound healing with no scar in the skin of sunda porcupine. In the present study, we noted that quill follicles appeared as dominant structure in the skin. The quill follicles were larger and showed complex structure when compared to that of the hair follicles. The quill follicles in the porcupine were consisted of high density of connective tissue and rich in fibroblast, a lot of keratinocytes lined the canal and around the follicles; a plenty amount of adipose / fat tissue, a well developed arrector muscles and sebaceous glands. One of the physiologic events present in the skin is wound healing process. Wound healing is a complex process in which many substances in the skin, such as blood vessel, connective tissue, leukocyte, cytokines and chemokines are involved. The hair follicles which are the main appendages of the mammalian skin has important roles in wound healing process, in some ways, such as source of the keratinocytes and fibroblast in closuring and repairing wound site; the hair cycle has implication to skin immune system; and modulation of the extracellular matrix around the hair follicles through cell-cell and cell-matrix interaction. The physiologic process in the skin that related to hair follicles should be also existed in quill follicles with considerably implication due to the size and complexity of the quill follicle structure. We suggest that scarless wound healing process in the porcupine skin might be closely related with the structure and function of the quill follicles.

Copyright

© 2018, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Andhika Y Prawira
AU  - Supratikno Supratikno
AU  - Savitri Novelina
AU  - Srihadi Agungpriyono
PY  - 2017/07
DA  - 2017/07
TI  - Hypothesis: Relationship of skin morphology and cutaneous scarless wound healing in sunda porcupine (Hystrix javanica)
BT  - Proceedings of the 1st International Conference in One Health (ICOH 2017)
PB  - Atlantis Press
SP  - 184
EP  - 188
SN  - 2468-5739
UR  - https://doi.org/10.2991/icoh-17.2018.36
DO  - 10.2991/icoh-17.2018.36
ID  - Prawira2017/07
ER  -