Proceedings of the 3rd International Conference on Biology, Science and Education (IcoBioSE 2021)

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Cardiac Histopathology of Male Mice (Mus musculus L.) Given Maximum Physical Exercise and Gambir Catechin (Uncaria gambir Roxb.)

Authors
Elsa Yuniarti1, *, M. Des1, Desi Fitria1, Pamelia Mayorita2
1Biology Department, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, Padang, West Sumatra, Indonesia
2Anatomical Pathology Department Dr. M. Djamil Central Hospital, Padang, Indonesia
*Corresponding author. Email: elsayuniarti@gmail.com
Corresponding Author
Elsa Yuniarti
Available Online 22 May 2023.
DOI
10.2991/978-94-6463-166-1_17How to use a DOI?
Keywords
Physical exercise; Gambir; Catechin
Abstract

Physical exercise is an activity carried out to maintain body health and fitness. However, optimal physical exercise will harm the body because it produces free radicals that can damage cells and body tissues. Gambir is a plant whose main component is catechin which functions as an antioxidant. Antioxidants in gambir can prevent the progression of heart disease and lipid peroxidation that produces malondialdehyde (MDA). This study aims to see the histology of the heart muscle of mice (Mus musculus L.) given maximum physical exercise and catechin of gambir (Uncaria gambir Roxb.) with concentrations of 80%, 90%, and 95%. The research was conducted at the Laboratory of Zoology and Anatomical Pathology, Faculty of Medicine, Universitas Andalas. The method used in making cardiac histology is the paraffin method with Hemaktoxilin-Eosin staining. Data were analyzed descriptively. The results showed that maximum physical exercise caused heart muscle damage. Furthermore, the higher the gambir catechin concentration, the better inhibiting free radical damage formed due to maximum physical exercise. The conclusion is that gambir catechin with a concentration of 95% with a dose of 100 mg is the best concentration and dose in repairing damage to the heart muscle.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 3rd International Conference on Biology, Science and Education (IcoBioSE 2021)
Series
Advances in Biological Sciences Research
Publication Date
22 May 2023
ISBN
978-94-6463-166-1
ISSN
2468-5747
DOI
10.2991/978-94-6463-166-1_17How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Elsa Yuniarti
AU  - M. Des
AU  - Desi Fitria
AU  - Pamelia Mayorita
PY  - 2023
DA  - 2023/05/22
TI  - Cardiac Histopathology of Male Mice (Mus musculus L.) Given Maximum Physical Exercise and Gambir Catechin (Uncaria gambir Roxb.)
BT  - Proceedings of the 3rd International Conference on Biology, Science and Education (IcoBioSE 2021)
PB  - Atlantis Press
SP  - 113
EP  - 120
SN  - 2468-5747
UR  - https://doi.org/10.2991/978-94-6463-166-1_17
DO  - 10.2991/978-94-6463-166-1_17
ID  - Yuniarti2023
ER  -