Correlations of Expression of KLF5, FHIT and DLG2 with Cervical Cancer

Alvionita Kogoya; Monica Dwi Hartanti

doi:10.2991/978-2-38476-273-6_132

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Correlations of Expression of KLF5, FHIT and DLG2 with Cervical Cancer

Authors

Alvionita Kogoya¹, Monica Dwi Hartanti¹^{, 2}^{, 3}^{, *}

¹Faculty of Medicine, Universitas Trisakti, West Jakarta, Jakarta, 11440, Indonesia

²Center for Artificial Intelligence and Advanced Technology, Universitas Trisakti, West Jakarta, Jakarta, 11440, Indonesia

³Center for Biomedical Research, The Research Organization for Health, National Research and Innovation Agency, Cibinong, West Java, 16911, Indonesia

^*Corresponding author. Email: mdhartanti@trisakti.ac.id

Corresponding Author

Monica Dwi Hartanti

Available Online 2 August 2024.

DOI: 10.2991/978-2-38476-273-6_132 How to use a DOI?
Keywords: KLF5; FHIT; DLG2; Cervical Cancer
Abstract: The fourth most common type of cancer in women, cervical cancer is brought on by the Hu-man Papillomavirus. Numerous genes, including KLF5, FHIT, and DLG2, have been linked to the advancement of cervical cancer, according to earlier research. The link between the KLF5, FHIT, and DLG2 genes in cervical cancer tissue is the focus of this investigation. Using a biopsy, cancer tissues were recovered. The RNA isolation, nanophotometer, and PCR methods were used to gather the cDNA samples. qPCR was used to analyse each sample. KLF5, FHIT, and DLG2 gene expression did not significantly correlate with cervical cancer (p > 0.05). The results of the Spearman's correlation test study indicated that the expression of the genes KLF5, FHIT, and DLG2 did not significantly correlate with the advancement of cervical cancer. This research may be a resource used in biomedical science to learn more about the genes linked to the development of cervical cancer. The KLF5, FHIT, and DLG2 genes can still be established as biomarkers for cervical cancer by increasing the sample size.
Open Access: Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title: Proceedings of 5th Borobudur International Symposium on Humanities and Social Science 2023
Series: Advances in Social Science, Education and Humanities Research
Publication Date: 2 August 2024
ISBN: 978-2-38476-273-6
ISSN: 2352-5398
DOI: 10.2991/978-2-38476-273-6_132 How to use a DOI?
Open Access: Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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ris enw bib

TY  - CONF
AU  - Alvionita Kogoya
AU  - Monica Dwi Hartanti
PY  - 2024
DA  - 2024/08/02
TI  - Correlations of Expression of KLF5, FHIT and DLG2 with Cervical Cancer
BT  - Proceedings of 5th Borobudur International Symposium on Humanities and Social Science 2023
PB  - Atlantis Press
SP  - 1302
EP  - 1309
SN  - 2352-5398
UR  - https://doi.org/10.2991/978-2-38476-273-6_132
DO  - 10.2991/978-2-38476-273-6_132
ID  - Kogoya2024
ER  -

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