Potential as Photoprotective, Antioxidant and Anti-inflammatory of Flavonoid Isolate from Okra Fruit (Abelmoschus esculentus L.)

DOI

10.2991/978-2-38476-273-6_33How to use a DOI?

Keywords

Photo protective; Antioxidant; Anti-inflammatory; Flavonoid; Okra fruit

Abstract

Long-term exposure to UV radiation can induce skin disorders, such as cancer and photo-allergic reactions. Natural products are being considered for their potential as non-irritating and effective sunscreen resources, owing to their UV absorption, antioxidant, and anti-inflammatory properties. This study aimed to assess the level of quercetin and investigate the in vitro ultraviolet radiation protection, antioxidant activity, and anti-inflammatory potential of isolated flavonoids from Okra Fruit (Abelmoschus esculentus L.). The results revealed that the average level of Okra fruit flavonoid isolate was 229.26 ± 1.16 µg/ml. In UV protection testing, at a concentration of 100 ppm, the SPF value was measured at 15.08, categorizing it as providing medium protection. Furthermore, the antioxidant activity test of the okra fruit flavonoid isolate yielded an IC50 value of 25.67 ppm, indicating a very strong antioxidant effect. The study demonstrated that the isolated compound inhibited protein denaturation at 50 ppm, with an inhibitory efficacy of 50.65%. Based on these findings, it can be concluded that the isolated compound possesses anti-inflammatory activity. There is a strong positive correlation between SPF effectiveness, antioxidant activity, anti-inflammatory effects, and flavonoid content.

Copyright

© 2024 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Christina Astutiningsih
AU  - Herni Setyawati
AU  - Ali Rahmat
AU  - Lilla Puji Lestari
AU  - Faidliyah Nilna Minah
PY  - 2024
DA  - 2024/08/02
TI  - Potential as Photoprotective, Antioxidant and Anti-inflammatory of Flavonoid Isolate from Okra Fruit (Abelmoschus esculentus L.)
BT  - Proceedings of 5th Borobudur International Symposium on Humanities and Social Science 2023
PB  - Atlantis Press
SP  - 281
EP  - 298
SN  - 2352-5398
UR  - https://doi.org/10.2991/978-2-38476-273-6_33
DO  - 10.2991/978-2-38476-273-6_33
ID  - Astutiningsih2024
ER  -