Artery Research

Renin-angiotensin blockade has reduced cardiovascular morbidity and mortality in hypertensive subjects. Experimental studies have shown that this blockade acts primarily on vascular tone, causing quasi simultaneously a decrease in vascular resistance, an increase in large artery compliance and a change...

Conventionally, the relationship between parent and daughter vessels at vascular bifurcations has been expressed by the junction exponent (x), and deviations of this parameter from the optimal conditions predicted by Murray’s law (x = 3) have been shown to be associated with vascular disease. However,...

Background: Accurate cardiovascular risk estimation in dialysis patients remains challenging because different pathogenetic mechanisms act simultaneously in this heterogeneous population. Radiographic calcification, aortic stiffness and wave reflection, have each individually been proven to be reliable...

Background: Vascular calcification is frequently found in hemodialysis patients. Fetuin-A is a well-characterized circulating inhibitor of calcification. Several other bone-associated proteins, such as the matrix Gla protein (MGP), osteoprotegerin (OPG), and osteopontin (OPN), are also presumed to inhibit...

There is increasing awareness that pulse wave velocity (PWV), an index of arterial stiffness, changes transiently via alteration of vascular smooth muscular tone. The aim of this study was to determine the effects of aging on the response of leg PWV to a low-intensity exercise bout. Ten older (69 ± 3...