P5.25 DIURNAL VARIATION OF CARDIO-ANKLE VASCULAR INDEX IN INDIVIDUALS WITH AND WITHOUT HEART DISEASE
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- 10.1016/j.artres.2013.10.173How to use a DOI?
- Abstract
Background: Clinical studies revealed age and pathological-related arterial stiffening. Arterial stiffening is associated with a higher risk of cardiovascular disease. Cardio-ankle vascular index (CAVI), which reflects both central elastic and peripheral muscular arterial stiffness, has been applied as a simple noninvasive method to evaluate the risk for cardiovascular events. However, whether it is necessary to standardize the time of the day when performing this measurement is unknown. We aim to examine the effect of daytime on CAVI in individuals with and without heart disease.
Methods: We investigated the daytime variation of CAVI using Vasera VS-1500N (Fukuda Denshi; Japan) in 23 healthy young individuals (28.3±4.7yr, HY), 22 healthy elderly individuals (61.1±9.0 yr, HE) and 25 patients with heart disease (63.9±11.5yr, HD).
Results: The effect of time on CAVI was shown to be significant in both univariate and multivariate analysis. Age was found as a significant determinant of CAVI (p<0.001). After adjustment for age, sex and MAP, CAVI was shown to be 4% (09:00 versus 13:00, p=0.022) and 5% higher (09:00 versus 17:00, p=0.002) in the morning than the following time points. Furthermore, the patterns of variation over the day showed no significant differences among groups in CAVI.
Conclusion: CAVI showed a significantly higher value in the morning, which provides further support to standardize the time for measurements of arterial stiffness using CAVI in routine clinical practice and longitudinal studies.
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Cite this article
TY - JOUR AU - Yanlei Li AU - Cordes Mareike AU - Hanssen Henner AU - Schmidt-Trucksäss Arno PY - 2013 DA - 2013/11/11 TI - P5.25 DIURNAL VARIATION OF CARDIO-ANKLE VASCULAR INDEX IN INDIVIDUALS WITH AND WITHOUT HEART DISEASE JO - Artery Research SP - 150 EP - 150 VL - 7 IS - 3-4 SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2013.10.173 DO - 10.1016/j.artres.2013.10.173 ID - Li2013 ER -