P8.9 EFFECT OF CARDIAC RESYNCHRONISATION THERAPY ON THE ARTERIAL STIFFNESS

DOI

10.1016/j.artres.2015.10.331How to use a DOI?

Abstract

Development of cardiac resynchronisation therapy (CRT) in recent years became a breakthrough in treatment of severe heart failure, as it improves exercise capacity, reduces a rate of hospitalisations due to heart failure exacerbation, and the mortality rate, as well as improves quality of patients’ life. However, data on CRT effects on a number of heart failure comorbidities remains scarce. The aim of this study was evaluation of CRT effect on the arterial stiffness.

Methods: The study covered a group of 55 patients (45 men and 10 women; mean age 67.04 ± 9.13 years) with chronic heart failure stable for at least last 3 months, in the NYHA functional class III or IV despite optimal pharmacotherapy, with a reduced left ventricular ejection fraction (LVEF) ≤ 35%, wide QRS complexes ≥ 120 ms. Before the resynchronisation system was implanted and after twelve months of observation arterial stiffness was evaluated with the carotid-femoral pulse wave velocity (PWV).

Results: Statistically significant changes weren’t demonstrated for carotid-femoral pulse wave velocity value, only a tendency for its reduction (11,73 ± 2,37 m/s vs 11,32 ± 2,78 m/s, p = 0,08).

Conclusions: After the resynchronisation system implantation, no statistically significant change in arterial stiffness was observed, only a trend towards its reduction.

Open Access

This is an open access article distributed under the CC BY-NC license.

TY  - JOUR
AU  - Anna Przybyla*
AU  - Danuta Czarnecka
PY  - 2015
DA  - 2015/11/23
TI  - P8.9 EFFECT OF CARDIAC RESYNCHRONISATION THERAPY ON THE ARTERIAL STIFFNESS
JO  - Artery Research
SP  - 36
EP  - 36
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.331
DO  - 10.1016/j.artres.2015.10.331
ID  - Przybyla*2015
ER  -