Artery Research

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Volume 12, Issue C, December 2015, Pages 36 - 36

P8.10 EFFECTS OF BARIATRIC SURGERY ON ENDOTHELIAL FUNCTION IN EXTREMELY OBESE PATIENTS

Authors
Anna Dzieża-Grudnik*, Anna Gαuszewska, Krzysztof Rewiuk, Aleksander Kwater, Bartosz Zarzycki, Maαgorzata Fedyk-Łukasik, Barbara Gryglewska, Tomasz Grodzicki
Department of Internal Medicine and Gerontology, Jagiellonian University, Medical College/University Hospital, Kraków, Poland
Available Online 23 November 2015.
DOI
10.1016/j.artres.2015.10.332How to use a DOI?
Abstract

Introduction: Bariatric surgery in extremely obese patients has influence on metabolic variables and body weight however data about influence on flow-mediated dilatation (FMD) of brachial artery are inconsistent.

The aim of the study was to assess the effect of bariatric surgery on endothelial function measured by flow-mediated dilatation.

Material and methods: We examined 35 patients with extreme obesity who met the eligibility criteria and underwent bariatric surgery (sleeve gastrectomy or Roux-en-Y Bypass).

Brachial flow-mediated dilatation was performed using linear-array transducer (GE Vivid 3, GE Healthcare Medical Diagnostics, Little Chalfont, UK).

Results: Data from 35 patients (34% men; age: 45+/−10) were collected. BMI decreased form 47,5 +/− 6 kg/m2 before surgery to 35,5 +/−5kg/m2 six months after surgery. FMD after six months has significantly improved. Median flow mediated dilatation before intervention was 6,5% (IQR 2–10,7) and after operation 8,5% (IQR 6,2–16,8). Improvement in FMD was higher in patients who underwent by-pass surgery (median 142% (IQR: 85–453)) in comparison to sleeve gastrectomy intervention (median 118% (IQR 67–246) but no statistical significance was observed between two groups.

Conclusions: Bariatric surgery resulted in significant improvement in endothelial function and may have potential impact on reduction of cardiovascular risk.

Open Access
This is an open access article distributed under the CC BY-NC license.

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Journal
Artery Research
Volume-Issue
12 - C
Pages
36 - 36
Publication Date
2015/11/23
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2015.10.332How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Anna Dzieża-Grudnik*
AU  - Anna Gαuszewska
AU  - Krzysztof Rewiuk
AU  - Aleksander Kwater
AU  - Bartosz Zarzycki
AU  - Maαgorzata Fedyk-Łukasik
AU  - Barbara Gryglewska
AU  - Tomasz Grodzicki
PY  - 2015
DA  - 2015/11/23
TI  - P8.10 EFFECTS OF BARIATRIC SURGERY ON ENDOTHELIAL FUNCTION IN EXTREMELY OBESE PATIENTS
JO  - Artery Research
SP  - 36
EP  - 36
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.332
DO  - 10.1016/j.artres.2015.10.332
ID  - Dzieża-Grudnik*2015
ER  -