Artery Research

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Volume 16, Issue C, December 2016, Pages 59 - 59

6.2 IMPACT OF DIABETES ON ARTERIAL STIFFNESS

Authors
Rogerio Toshiro Passos Okawa, Jorge Juarez Vieira Teixeira, Alex Cardoso Perez, Eigi Wilton de Souza, Giovanna Chiqueto Duarte, Guilherme Norio Hayakawa, Lorena Lima Gargaro, Marina Franciscon Gomes da Cruz, Michel Lima Moro Alves, Milene Cripa Pizatto de Araujo, Patrick Sadao Nishikawa, Rafaela Pelisson Regla, Rafael Campos do Nascimento
State University of Maringa, Maringa, Brazil
Available Online 24 November 2016.
DOI
10.1016/j.artres.2016.10.038How to use a DOI?
Abstract

Objectives/Background: The purpose of our study was to examine the impact of diabetes on arterial stiffness.

A systematic review, published by Cecelja and Chowienczyk (1), describes that pulse wave velocity (PWV), is highly predictive of cardiovascular events, and PWV is associated with age and blood-pressure, but other pressure- independent risk factors including: dyslipidemia, smoking, diabetes, obesity remain inconsistent in many studies.

Methods: We included 796 patients, 398 of whom had diabetes. Patients were separated according to age, and we used the normal values for PWV described by Boutouyrie et al (2) .We analyzed time of disease, diabetes control, and their impact on PWV.

A Mobil- o -Graph device was used to analyze the PWV, and a Stata 9.0 software was used for the statistics analysis.

Results: We found that diabetes is associated with an increase in PWV (OR: 1.6 p<0.01) and the diabetes control also had influence in the PWV increase, which means that an glycated hemoglobin above 7.0 % had an OR: 2.4, p< 0,001.

When we analysed the time of diabetes diagnosis, the longer duration of disease (> 120 months) had thirty- eight times more risk to increase the PWV, and those that had been diagnosed between 61 to 119 months had approximately three times more risk to increase the PWV.

Conclusions: In our study we found that diabetes had increased the pulse wave velocity.

Diabetes control and duration of disease also had impact on arterial stiffness.

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This is an open access article distributed under the CC BY-NC license.

References

1.Marina Cecelja Philip Chowienczyk, Dissociation of aortic pulse wave velocity with risk factors for cardiovascular disease other than hypertension: a systematic review, Hypertension, Vol. 54, No. 6, Dec 2009, pp. 1328 36.
2.Boutoyrie Pierre et al., Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: ‘establishing normal and reference values’, Eur Heart J, Vol. 31, No. 19, Oct 2010, pp. 2338-2350.
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Journal
Artery Research
Volume-Issue
16 - C
Pages
59 - 59
Publication Date
2016/11/24
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2016.10.038How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Rogerio Toshiro Passos Okawa
AU  - Jorge Juarez Vieira Teixeira
AU  - Alex Cardoso Perez
AU  - Eigi Wilton de Souza
AU  - Giovanna Chiqueto Duarte
AU  - Guilherme Norio Hayakawa
AU  - Lorena Lima Gargaro
AU  - Marina Franciscon Gomes da Cruz
AU  - Michel Lima Moro Alves
AU  - Milene Cripa Pizatto de Araujo
AU  - Patrick Sadao Nishikawa
AU  - Rafaela Pelisson Regla
AU  - Rafael Campos do Nascimento
PY  - 2016
DA  - 2016/11/24
TI  - 6.2 IMPACT OF DIABETES ON ARTERIAL STIFFNESS
JO  - Artery Research
SP  - 59
EP  - 59
VL  - 16
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2016.10.038
DO  - 10.1016/j.artres.2016.10.038
ID  - Okawa2016
ER  -