P113 DIASTOLIC AMBULATORY BLOOD PRESSURE PARAMETERS ARE ASSOCIATED WITH VALVE CALCIFICATION IN PATIENTS WITH END-STAGE RENAL DISEASE ON MAINTENANCE HEMODIALYSIS
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- 10.1016/j.artres.2017.10.144How to use a DOI?
- Abstract
Objective: Valve calcification (VC) is common in patients on hemodialysis and increases the risk of cardiovascular morbidity and mortality. The aim if the study was to evaluate the association between VC and 44-hour ambulatory blood pressure (ABP) variables.
Materials and methods: In 68 patients with end-stage renal disease (ESRD) on maintenance hemodialysis (45.6% males, median age 58.3 (interquartile range (IQR) 54.6; 61.6) years, dialysis duration 62.7 (47.8; 77) months, arterial hypertension 94%, heart failure 28%, diabetes mellitus 21%, glomerulonephritis 35%, pyelonephritis 25%, multicystic dysplastic kidney 13%) echocardiography and 44-hour ABP monitoring was performed. Mann-Whitney test was considered significant if p < 0.05.
Results: Calcification of the aortic (AVC), mitral (MVC) and both valves was revealed in 46 (67.6%), 34 (50%) and 33 (48.5%) of patients. 20 (29%) patients had no signs of VC. Patients with vs without AVC had lower daytime diastolic BP (DBP) (79±13 vs 89±12 mmHg, p < 0.01), nighttime DBP (75±13 vs 83±13 mmHg, p < 0.05), day one DBP (77±13 vs 89±15 mmHg, p < 0.01), day two DBP (79±14 vs 88±10 mmHg, p < 0.01), 44-hour DBP (78±13 vs 88±12 mmHg, p < 0.01).
Patients with vs without MVC had lower daytime DBP (78±15 vs 86±11 mmHg, p < 0.01), nighttime DBP (74±14 vs 81±12 mmHg, p < 0.05), 44-hour DBP (77±15 vs 85±11 mmHg, p < 0.01), higher daytime DBP variability (10±3 vs 9±3 mmHg, p < 0.01).
Conclusion: High prevalence of valve calcification (71%) was revealed in patients with ESRD on hemodialysis. Patients with VC were older, had higher duration of dialysis, lower values of ambulatory DBP.
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Cite this article
TY - JOUR AU - Maria Trukhanova AU - Nadezhda Manukhina AU - Dmitry Doroshenko AU - Svetlana Villevalde AU - Zhanna Kobalava PY - 2017 DA - 2017/12/06 TI - P113 DIASTOLIC AMBULATORY BLOOD PRESSURE PARAMETERS ARE ASSOCIATED WITH VALVE CALCIFICATION IN PATIENTS WITH END-STAGE RENAL DISEASE ON MAINTENANCE HEMODIALYSIS JO - Artery Research SP - 93 EP - 93 VL - 20 IS - C SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2017.10.144 DO - 10.1016/j.artres.2017.10.144 ID - Trukhanova2017 ER -