P155 DETERMINANTS OF PULSE WAVE VELOCITY IN CHILDREN

Cristina Silva; Mariana Formigo; Nuno Formigo; Sara Freitas; Cristina Cunha; Margarida Rocha; Clarisse Neves; Laura Castro; Filipe Gonçalves; Maria J. Cotter; Pedro G. Cunha; Jorge Cotter

doi:10.1016/j.artres.2018.10.208

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Volume 24, Issue C, December 2018, Pages 125 - 125

P155 DETERMINANTS OF PULSE WAVE VELOCITY IN CHILDREN

Authors

Cristina Silva¹, Mariana Formigo¹, Nuno Formigo²^{, 3}, Sara Freitas¹, Cristina Cunha¹, Margarida Rocha¹, Clarisse Neves¹, Laura Castro¹, Filipe Gonçalves¹, Maria J. Cotter⁴, Pedro G. Cunha¹^{, 5}^{, 6}, Jorge Cotter¹^{, 5}^{, 6}

¹Center for the Research and Treatment of Arterial Hypertension and Cardiovascular Risk, Hospital Senhora da Oliveira, Guimarães, Portugal

²Department of Biology, Faculty of Sciences of University of Porto, Portugal

³CIIMAR - Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Portugal

⁴Department of Natural Sciences, Escola E.B. 2,3 João de Meira, Guimarães, Portugal

⁵Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal

⁶ICVS/3B’s - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Available Online 4 December 2018.

DOI: 10.1016/j.artres.2018.10.208 How to use a DOI?
Abstract: Background: Arterial stiffening measured by Pulse Wave Velocity (PWV) predicts cardiovascular events and mortality in adults. It advances with age and seems accelerated in children with certain disease conditions such as chronic kidney disease or diabetes. The aim of this study was to determine factors that influence PWV in children.

Methods: PWV was captured in 285 children aged 10–14 years attending a Portuguese school. The effects of sex, age, height, weight, body mass index, waist circumference, blood pressure, heart rate and sodium excretion in 24-h urinary samples in PWV were tested.

Results: PWV correlated positively with age, height, systolic blood pressure, diastolic blood pressure and heart rate in males and females (p < 0.05) and with weight in males (p < 0.05). Major predictors for PWV in a multivariate regression analysis were gender, height, weight, diastolic blood pressure, heart rate and body mass index.

Conclusion: Our study found several determinants of PWV in children, some of them modifiable and interfering with cardiovascular outcomes. Future research may provide clarity to the association between PWV in children and cardiovascular events in adulthood.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 24 - C
Pages: 125 - 125
Publication Date: 2018/12/04
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2018.10.208 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

Cite this article

ris enw bib

TY  - JOUR
AU  - Cristina Silva
AU  - Mariana Formigo
AU  - Nuno Formigo
AU  - Sara Freitas
AU  - Cristina Cunha
AU  - Margarida Rocha
AU  - Clarisse Neves
AU  - Laura Castro
AU  - Filipe Gonçalves
AU  - Maria J. Cotter
AU  - Pedro G. Cunha
AU  - Jorge Cotter
PY  - 2018
DA  - 2018/12/04
TI  - P155 DETERMINANTS OF PULSE WAVE VELOCITY IN CHILDREN
JO  - Artery Research
SP  - 125
EP  - 125
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.208
DO  - 10.1016/j.artres.2018.10.208
ID  - Silva2018
ER  -

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