P154 DOES THE METHOD OF THE MEASUREMENT OF BLOOD PRESSURE CORRELATES DIFFERENTLY WITH PULSE WAVE VELOCITY IN RESISTANT HYPERTENSION?

Jose Mesquita Bastos; Susana Lopes; Catarina Garcia; Verónica Ribau; Susana Bertoquini; Cátia Leitão; P. Ribeiro Ilda; Daniela Figueiredo; L. Viana João; Fernando Ribeiro; Jorge Polónia

doi:10.1016/j.artres.2018.10.207

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Volume 24, Issue C, December 2018, Pages 124 - 125

P154 DOES THE METHOD OF THE MEASUREMENT OF BLOOD PRESSURE CORRELATES DIFFERENTLY WITH PULSE WAVE VELOCITY IN RESISTANT HYPERTENSION?

Authors

Jose Mesquita Bastos¹^{, 2}, Susana Lopes³, Catarina Garcia⁴, Verónica Ribau⁵, Susana Bertoquini⁶, Cátia Leitão⁷, P. Ribeiro Ilda⁸, Daniela Figueiredo⁹, L. Viana João¹⁰, Fernando Ribeiro¹¹, Jorge Polónia⁶

¹Cardiology Department, Hospital Infante D. Pedro, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal

²School of Health Sciences and CINTESIS@UA, University of Aveiro, Aveiro, Portugal

³3-School of Health Sciences and Institute of Biomedicine – iBiMED, University of Aveiro, Aveiro, Portugal

⁴Research Center in Sports Sciences, Health and Human Development, CIDESD, University Institute of Maia, Maia, Portugal

⁵Cardiology Department, Hospital Infante D. Pedro, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal

⁶Hypertension Unit, Hospital Pedro Hispano, Matosinhos, Faculty of Medicine of the University of Porto (FMUP), Center for Health Technology and Services Research (CINTESIS), University of Porto, Porto, Portugal

⁷Departmente of Physics & I3N and Instituto de Telecomunicações, University of Aveiro, Portugal

⁸Center of Investigation on Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra, Center for Neuroscience and Cell Biology and Institute for Biomedical Imaging and Life Sciences (CNC.IBILI), Coimbra, Portugal

⁹School of Health Sciences and CINTESIS@UA, University of Aveiro, Aveiro, Portugal

¹⁰Research Center in Sports Sciences, Health and Human Development, CIDESD, University Institute of Maia, Maia, Portugal

¹¹School of Health Sciences and Institute of Biomedicine – iBiMED, University of Aveiro, Aveiro, Portugal

Available Online 4 December 2018.

DOI: 10.1016/j.artres.2018.10.207 How to use a DOI?
Abstract: Objective: Carotid-femoral Pulse Wave velocity (cfPWV), the gold standard for measuring stiffness, is a marker of organ damage (OLD). Even though cfPWV correlates with casual (BPc), central (CBP) and ambulatory (ABPM) blood pressure (BP), evidence is limited for resistant hypertension (RH).

Method: Thirty-three patients (age, 56.1 ± 8.2 years; weight, 78.0 ± 12.4 kg; height, 1.62 ± 0.08 m) with RH participated in a cross-sectional study. Outcomes included clinical data, BPc, ABPM, and carotid-femoral, cfPWV. Correlation analysis was conducted to assess the association between variables; independent t-tests were conducted to compare variables between those participants with cfPWV < and ≥ 10 m/s.

Results: Patients (20 women and 13 men) presented a peripheral systolic and diastolic BPc of 144.0 ± 3.8 mmHg and 82.0 ± 1.9 mmHg, respectively. The cfPWV correlated with age (r = 0.356, p = 0.045), 24 h systolic BP (24 h SBP) nightime pulse pressure (night PP), 24 h pulse pressure (24hPP), casual systolic (SBPc) and diastolic BP (DBPc), central systolic (CSBP), diastolic (CDBP) and central pulse pressure (CPP); controlled for age the correlation remained significant for 24h SBP (r=0.446, p=0.009) 24hPP (r=0.464, p=0.007), nightPP (r=0.365, p=0.036), SBPc (r=0.620, p<0.001), DBPc (r=0.488, p=0.004), PPc (r=0.592, p<0.001), central SBP (r=0.587, p<0.001), central DBP (r=0.487, p=0.001) and central PP (r=0.506, p=0.003). Patients with lower values of cfPWV (n=26) showed lower SBPc (142.8 ± 15.9 vs. 162.6 ± 30.9 mmHg, p=0.025), central SBP (136.0 ± 15.7 vs. 154.1 ± 31.8 mmHg, p=0.041) and PP (49.6 ± 9.5 vs. 60.9 ± 20.8 mmHg, p=0.043) than patients with cfPWV≥10 m/s (n=7).

Conclusion: Our data shows that cfPWV correlates with SBPc, 24hSBP, 24hPP and CSBP, after controlled for age, in patients with RH.
Open Access: This is an open access article distributed under the CC BY-NC license.

Acknowledgments:

This work is financed by FEDER Funds through the Operational Competitiveness Factors Program - COMPETE and by National Funds through FCT - Foundation for Science and Technology within the project "PTDC/DTP-DES/1725/2014".

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Journal: Artery Research
Volume-Issue: 24 - C
Pages: 124 - 125
Publication Date: 2018/12/04
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2018.10.207 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

Cite this article

ris enw bib

TY  - JOUR
AU  - Jose Mesquita Bastos
AU  - Susana Lopes
AU  - Catarina Garcia
AU  - Verónica Ribau
AU  - Susana Bertoquini
AU  - Cátia Leitão
AU  - P. Ribeiro Ilda
AU  - Daniela Figueiredo
AU  - L. Viana João
AU  - Fernando Ribeiro
AU  - Jorge Polónia
PY  - 2018
DA  - 2018/12/04
TI  - P154 DOES THE METHOD OF THE MEASUREMENT OF BLOOD PRESSURE CORRELATES DIFFERENTLY WITH PULSE WAVE VELOCITY IN RESISTANT HYPERTENSION?
JO  - Artery Research
SP  - 124
EP  - 125
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.207
DO  - 10.1016/j.artres.2018.10.207
ID  - MesquitaBastos2018
ER  -

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