Artery Research

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Volume 2, Issue 3, August 2008, Pages 102 - 102

P1.43 FRAMINGHAM SCORE UNDERDIAGNOSES VASCULAR DISEASE IN PATIENTS UNDER CARDIOVASCULAR PREVENTION

Authors
P. Forcada1, C. Kotliar1, S. Obregon1, O. Montana2, C. Schulte2, G. Millet1, J. Guerrieri1, D. Turri1
1Hospital Universitario Austral, Pilar, Buenos Aires, Argentina
2Clinica Dim, Buenos Aires, Argentina
Available Online 15 September 2008.
DOI
10.1016/j.artres.2008.08.350How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Aim: Framingham score (FS) is used in clinical practice to estimate the CV risk of complications and is used as reference to evaluate new markers of CV risk. Recently ESH/ESC 07 guidelines stressed on the evaluation of subclinical vascular disease (VD). We analyzed, using an integrative ultrasound evaluation, the severity of VD according to increasing FS levels of risk.

Methods: We did in the same procedure 1) CIMT 2) Plaques characterization, 3) PWV and 4) FMD with a strict quality control. We set a score (VS) from 0 to 5 according to the severity of the VD. The FS was obtained from medical records.

Results: We performed a cross sectional, observational study on 702 p.(54 + 13y.o.,448(64%) males).FS was high(>20%) for 216p. (30,8%), moderate(10–20%) for 204p.(29%), and low (<10%) for 282p.(40,2%).

Parameter FS Low FS Moderate FS High p
Age 44 ± 12 57 ± 8 64 ± 9 < 001
Sex (% males) 53 68 74 < 001
SBP 134 ± 16 150 ± 15 145 ± 18 < 001
DBP 82 ± 10 85 ± 10 86 ± 10 < 001
Left IMT (mm) 0.66 ± 0.16 0.78 ± 0.17 0.87 ± 0.2 < 001
Right IMT (mm) 0.63 ± 0.13 0.75 ± 0.15 0.84 +v0.2 < 001
% Plaques 30 55 31 < 001
%Abnormal FMD 32 36 44 .02
PWV (mts / sec) 9 ± 3 10 ± 3 13 ± 6 < 001
Vascular Score (mean) 1,9 ± 1,3 2,5 ± 1,3 3,1 ± 1,3 < 001

Conclusions: 1- The higher the FS, the more the severity of the VD increases.2-Although, we have found 54,2% with a low FS with moderate to severe VS and 18% of pts. with severe VD classified as low to moderate clinical risk.

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Journal
Artery Research
Volume-Issue
2 - 3
Pages
102 - 102
Publication Date
2008/09/15
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2008.08.350How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - P. Forcada
AU  - C. Kotliar
AU  - S. Obregon
AU  - O. Montana
AU  - C. Schulte
AU  - G. Millet
AU  - J. Guerrieri
AU  - D. Turri
PY  - 2008
DA  - 2008/09/15
TI  - P1.43 FRAMINGHAM SCORE UNDERDIAGNOSES VASCULAR DISEASE IN PATIENTS UNDER CARDIOVASCULAR PREVENTION
JO  - Artery Research
SP  - 102
EP  - 102
VL  - 2
IS  - 3
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2008.08.350
DO  - 10.1016/j.artres.2008.08.350
ID  - Forcada2008
ER  -