Artery Research

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Volume 2, Issue 3, August 2008, Pages 102 - 103

P1.44 EARLY DETECTION OF ATHEROSCLEROTIC DISEASE IN MILD HYPERTENSIVE PATIENTS: A STRONG REASON TO REEVALUATE CARDIOVASCULAR RISK

Authors
P. Forcada1, C. Kotliar1, O. Montana2, C. Schulte2, G. Millet1, S. Obregon1, J. Guerrieri1, D. Turri1
1Hospital Univedrsitario Austral, Pilar, Buenos Aires, Argentina
2Clinica Dim, Buenos Aires, Argentina
Available Online 15 September 2008.
DOI
10.1016/j.artres.2008.08.351How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Aim: To analyze the incidence and severity of subclinical vascular disease (VD) using ultrasonography in patients (p.) with essential hypertension (HT).

Methods: We did in the same procedure 1) CIMT 2) Plaques characterization, 3) PWV and 4) FMD with a strict quality control. We set a score (VS) from 0 to 5 according to the severity of the VD. The CV Risk using Framingham score (FS) was also obtained from medical records.

Results: We did a cross sectional, observational study on 604 p. (479 with stage I-II HT (ESH 07) 53,2 + 13 y.o., 63% males and 125 normotensive NT controls 51,7 + 14 y.o. p.003, 62% males p NS)

Parameter HT (n= 479) NT (n= 125) p
SBP (mmHg) 143 ± 16 128 ± 15 < 001
DBP (mmHg) 86 ± 9 77 ± 8 < 001
HR (bpm) 70 ± 10 69 ± 9 NS
Left CIMT (mm) 0.75 ± 0.19 0.72 ± 0.10 NS
Right CIMT (mm) 0.72 ± 0.19 0.70 ± 0.19 NS
% abnormal CIMT 29 19 .02
% Plaques 49 46 NS
%Abnormal FMD 39 26 .006
PWV (mts / sec) 10,5 ± 4,3 10 ± 4 < 001
%Abnormal PWV 34 42 NS
FS (mean) 12 ± 8 8 ± 6 .001
VS (mean) 2,4 ± 1,4 2,1 ± 1,4 < 001

Conclusions: 1-Subclinical vascular disease is more frequent and severe in HT patients.2- Indicators of subclinical vascular disease in this subset of p. allow a more precise diagnosis of subclinical vascular. (ESC/ESH guidelines 2007)3-Vascular score of severity is higher in HT p. than in NT.

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Journal
Artery Research
Volume-Issue
2 - 3
Pages
102 - 103
Publication Date
2008/09/15
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2008.08.351How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - P. Forcada
AU  - C. Kotliar
AU  - O. Montana
AU  - C. Schulte
AU  - G. Millet
AU  - S. Obregon
AU  - J. Guerrieri
AU  - D. Turri
PY  - 2008
DA  - 2008/09/15
TI  - P1.44 EARLY DETECTION OF ATHEROSCLEROTIC DISEASE IN MILD HYPERTENSIVE PATIENTS: A STRONG REASON TO REEVALUATE CARDIOVASCULAR RISK
JO  - Artery Research
SP  - 102
EP  - 103
VL  - 2
IS  - 3
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2008.08.351
DO  - 10.1016/j.artres.2008.08.351
ID  - Forcada2008
ER  -