P1.09 RESULTS OF THE TWO METHODS OF AORTIC STIFFNESS ESTIMATION IN YOUNG AND MIDDLE AGED PATIENTS WITH CORONARY ARTERY DISEASE

DOI

10.1016/j.artres.2009.10.012How to use a DOI?

Abstract

Aim: The assessment of aortic stiffness in young and middle aged men with coronary artery disease (CAD).

Materials and methods: This study was carried out in 49 CAD patients aged 43,5±4,8 years with coronary artery stenosis diagnosed by angiography and 29 healthy volunteers (the control group) aged 43,1±5,9 years. The patients with arterial hypertension, diabetes mellitus, and hypercholesterolemia were not included in this study. The determination of aortic pulse wave velocity (PWV) was carried out by aorta ultrasound duplex scanning and by “Arteriograph”(TensioMed, Hungary).

Results: Aortic PWV in the control group was 4.4–7.8 (average 5,8±0,9m/s), median 5,6m/s, the upper quartile 6,5m/s, which was used as the upper normal level. Aortic PWV in CAD patients was 4,6–10 (average 6,8±1,3m/s, p<0.001), median - 6,9m/s. Aortic PWV was higher than 6,5m/s in 53% CAD patients and in 24% from control group (p=0,02). PWV in CAD patients with 1,2 and 3 coronary artery damage was respectively 6,0±1,1, 6,7±1,1 и 7,7±1,2m/s. According to the measurement by “Arteriograph” PWV in CAD patients was on average 8,8±2,4m/s, and 8,1±2,2m/s (p=2,21) in control group. Increased PWV was detected in 33% CAD patients and in 21% in the control group (p=0,43). The significant PWV differences in CAD patients with the 1,2 and 3 coronary artery damage were not exposed.

Conclusion: aortic PWV assessment by ultrasound duplex scanning but not by “Arteriograph” indicated the relation of arterial stiffness with the existence and severity of CAD in young and middle aged men.

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TY  - JOUR
AU  - M.V. Andreevskaya
AU  - Machmudova KhA
AU  - N.M. Moiseeva
AU  - S.G. Kozlov
AU  - T.V. Balakhonova
AU  - M.A. Saidova
AU  - A.N. Rogoza
PY  - 2009
DA  - 2009/12/03
TI  - P1.09 RESULTS OF THE TWO METHODS OF AORTIC STIFFNESS ESTIMATION IN YOUNG AND MIDDLE AGED PATIENTS WITH CORONARY ARTERY DISEASE
JO  - Artery Research
SP  - 163
EP  - 163
VL  - 3
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2009.10.012
DO  - 10.1016/j.artres.2009.10.012
ID  - Andreevskaya2009
ER  -