P2.02 THE METABOLIC SYNDROME IN MIDDLE AGED INDIVIDUALS IS ASSOCIATED WITH GREATER ELASTIC, BUT NOT MUSCULAR ARTERIAL STIFFNESS

V. Dzenkeviciute; L. Ryliskyte; Z. Petrulioniene; J. Badariene; A. Laucevicius

doi:10.1016/j.artres.2009.10.018

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Volume 3, Issue 4, December 2009, Pages 177 - 177

P2.02 THE METABOLIC SYNDROME IN MIDDLE AGED INDIVIDUALS IS ASSOCIATED WITH GREATER ELASTIC, BUT NOT MUSCULAR ARTERIAL STIFFNESS

Authors

V. Dzenkeviciute¹, L. Ryliskyte¹, Z. Petrulioniene¹, J. Badariene², A. Laucevicius¹

¹Vilnius University, medical faculty, clinic of Heart and vascular diseases, Vilnius, Lithuania

²Vilnius University Hospital Santariskiu klinikos, Cardiology and Angiology department, Vilnius, Lithuania

Available Online 3 December 2009.

DOI: 10.1016/j.artres.2009.10.018 How to use a DOI?
Abstract: There is some evidence that in MetS increase of arterial stiffness may be distributed over muscular and the elastic arteries not uniformly.

The purpose of this study was to examine the association between the MS and arterial stiffness of both elastic and muscular arteries in middle aged individuals.

Methods: The cohort consisted of 951 individuals without MetS (females 338 and males 613), mean ages 54.15±5.88 and 604 with MetS (females 405 and males 199), mean ages 54.41±5.97 (p=0.69). For this investigation all those with diabetes were excluded. MetS defined according to the ATP III criteria. Following 10min supine rest, blood pressure, carotid-femoral and carotid-radial PWV (using Sphygmocor v.7) and cardiovascular index CAVI (VaSera VS-100) were measured. All patients underwent detailed assessment of cardiovascular risk factors.

Results: Aortic PWV in the MetS group (9.02 +/− 1.53m/s) was significantly higher (P<0.001) than in patients without MetS (8.67 +/− 1.58m/s). There were no significant between-group differences of carotid-radial PWV (MetS 8.92. +/− 1.21m/s, without MetS: 8.95 +/− 1.4m/s; p=0.53) or CAVI (MetS: 7.93 +/− 3.2m/s, non-MetS: 8.18 +/− 6m/s; p=0.46) values. In this study multiple logistic regression revealed that aortic but not carotid-radial PWV and CAVI were independently related to MetS (standardized regression parameter r=−1.25, p= 0.0049 after adjusting for age, gender).

Conclusions: the results therefore indicated that elastic arteries may stiffen preferentially over muscular arteries in middle aged individuals with the metabolic syndrome.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 3 - 4
Pages: 177 - 177
Publication Date: 2009/12/03
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2009.10.018 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - V. Dzenkeviciute
AU  - L. Ryliskyte
AU  - Z. Petrulioniene
AU  - J. Badariene
AU  - A. Laucevicius
PY  - 2009
DA  - 2009/12/03
TI  - P2.02 THE METABOLIC SYNDROME IN MIDDLE AGED INDIVIDUALS IS ASSOCIATED WITH GREATER ELASTIC, BUT NOT MUSCULAR ARTERIAL STIFFNESS
JO  - Artery Research
SP  - 177
EP  - 177
VL  - 3
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2009.10.018
DO  - 10.1016/j.artres.2009.10.018
ID  - Dzenkeviciute2009
ER  -

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