Artery Research

<Previous Article In Issue
Next Article In Issue>
Volume 8, Issue 2, June 2014, Pages 51 - 56

A comparative study on the mechanical properties of the umbilical vein and umbilical artery under uniaxial loading

Authors
Alireza Karimia, b, c, Mahdi Navidbakhsha, b, *, Mansour Alizadehb, Ahmad Shojaeic, d
aTissue Engineering and Biological Systems Research Lab, School of Mechanical Engineering, Iran University of Science and Technology, Tehran 16846, Iran
bSchool of Mechanical Engineering, Iran University of Science and Technology, Tehran 16846, Iran
cResearch Department, Basir Eye Center, Tehran 14186, Iran
dDepartment of Ophthalmology, Baqiyatallah University of Medical Sciences, Tehran 14155, Iran
*Corresponding author. School of Mechanical Engineering, Iran University of Science and Technology, Tehran 16846, Iran. Tel.: +98 21 77209027; fax: +98 21 73021585. E-mail addresses: alirezakarimi@mecheng.iust.ac.ir (A. Karimi), mnavid@iust.ac.ir (M. Navidbakhsh).
Corresponding Author
Mahdi Navidbakhsh
Received 7 January 2014, Revised 7 February 2014, Accepted 10 February 2014, Available Online 28 February 2014.
DOI
10.1016/j.artres.2014.02.001How to use a DOI?
Keywords
Umbilical vein; Umbilical artery; Mechanical properties; Hyperelastic; Constitutive modeling
Abstract

Purpose: Coronary Artery Disease (CAD) is the main cause of mortalities worldwide. The Saphenous Vein (SV) and Umbilical Vein (UV) are the most common veins using for treatment as a Coronary Artery Bypass Graft (CABG). The mechanical properties of UV owing to its long-term patency for CABG are deemed important. However, there is a lack of knowledge on the mechanical properties of UV. In this study, the linear (Young’s modulus and maximum stress) and nonlinear (hyperelastic material coefficients) mechanical properties of 8 human umbilical vein and umbilical artery (UA) are investigated using a series of uniaxial tensile tests. The nonlinear mechanical behavior of UV/UA is computationally investigated using hyperelastic strain energy density functions, including Mooney-Rivlin and Ogden. A hyperelastic constitutive model is selected to best fit the axial behavior of the UV/UA.

Results: The results reveal that the Young’s modulus and maximum stress of UA are 342% and 19% more than that of UV, respectively. The Mooney-Rivlin material model is selected to represent the nonlinear behavior of the UV and UA which can be used in future biomechanical simulations of the umbilical vein and umbilical artery.

Conclusions: The higher mechanical properties of umbilical artery compared to umbilical vein might have related to the amount of elastin and collagen content on the UA wall. The results of this study could be utilized to understand the extension and rupture mechanism of UV and UA, and has implications for interventions and surgeries, including balloon-angioplasty, bypass, and stenting.

Copyright
© 2014 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

Download article (PDF)
View full text (HTML)

<Previous Article In Issue
Next Article In Issue>
Journal
Artery Research
Volume-Issue
8 - 2
Pages
51 - 56
Publication Date
2014/02/28
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2014.02.001How to use a DOI?
Copyright
© 2014 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Alireza Karimi
AU  - Mahdi Navidbakhsh
AU  - Mansour Alizadeh
AU  - Ahmad Shojaei
PY  - 2014
DA  - 2014/02/28
TI  - A comparative study on the mechanical properties of the umbilical vein and umbilical artery under uniaxial loading
JO  - Artery Research
SP  - 51
EP  - 56
VL  - 8
IS  - 2
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2014.02.001
DO  - 10.1016/j.artres.2014.02.001
ID  - Karimi2014
ER  -