The acute effects of mental arithmetic, cold pressor and maximal voluntary contraction on arterial stiffness in young healthy subjects

Noor-Ahmed Jatoi; Stella-Maria Kyvelou; John Feely

doi:10.1016/j.artres.2014.02.002

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Volume 8, Issue 2, June 2014, Pages 44 - 50

The acute effects of mental arithmetic, cold pressor and maximal voluntary contraction on arterial stiffness in young healthy subjects

Authors

Noor-Ahmed Jatoi^a^{, b}^{, c}^{, *}, Stella-Maria Kyvelou^b, John Feely^c^{, d}

^aDepartment of Clinical Pharmacology/Internal Medicine, College of Medicine, & King Fahd University Hospital, University of Dammam, Dammam, Saudi Arabia

^bDepartment of Medicine, School of Medicine, Clinical Sciences Institute, National University of Ireland Galway & Galway University Hospital, Galway, Ireland

^cDepartment of Clinical Pharmacology & Therapeutics, Trinity Center for Health Sciences & Hypertension Clinic, St. James’s Hospital, Dublin, Ireland

^d

Deceased.

^*Corresponding author. Department of Clinical Pharmacology/Internal Medicine, College of Medicine, & King Fahd University Hospital, University of Dammam, Dammam, Saudi Arabia. Tel./fax: +966 3 31070. E-mail address: jatoina@hotmail.com (N.-A. Jatoi).

Corresponding Author

Noor-Ahmed Jatoi

Received 2 September 2012, Revised 18 February 2014, Accepted 26 February 2014, Available Online 20 March 2014.

DOI: 10.1016/j.artres.2014.02.002 How to use a DOI?
Keywords: Mental stress; Cold pressor; Dynamic exercise; Blood pressure; Augmentation index; Pulse wave velocity
Abstract: Background: Mental stress, dynamic exercise and cold pressor stimulation all increase blood pressure (BP); however, their effects on arterial stiffness are not well described.

Methods: Twenty-three young healthy subjects (14 female/9 males), aged 18–30 years (23 ± 3 years), underwent mental arithmetic stress (mental arithmetic test [MAT]), cold presser test (CPT) and dynamic exercise (30% of maximal voluntary contraction [30% MVC]). Blood pressure and indices of arterial stiffness, pulse wave velocity (PWV; m/sec) and augmentation index (AIx; %) were measured at baseline, during the intervention (MAT, CPT and 30% MVC), and at 5 min and 10 min after the end of the intervention on separate days within a 3-week period. All values are given as means and standard deviations; statistical analysis was carried out using JMP software (Version 7).

Results: During MAT, CPT and 30% MVC there were respective increases in heart rate (HR/min) 27%, 16% and 10% (P < 0.001); systolic BP 16%, 17% and 12% (P < 0.01); diastolic BP 15%, 23% and 15% (P < 0.01); AIx 13%, 29% and 30% (P < 0.05); and PWV 14%, 12% and 16% (P < 0.01). When the model was corrected for HR, systolic BP and diastolic BP the changes both in PWV and AIx remained significant (P < 0.01).

Conclusions: MAT, CPT and 30% MVC each increase the indices of arterial stiffness independently of HR and baseline blood pressure levels.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 8 - 2
Pages: 44 - 50
Publication Date: 2014/03/20
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2014.02.002 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - Noor-Ahmed Jatoi
AU  - Stella-Maria Kyvelou
AU  - John Feely
PY  - 2014
DA  - 2014/03/20
TI  - The acute effects of mental arithmetic, cold pressor and maximal voluntary contraction on arterial stiffness in young healthy subjects
JO  - Artery Research
SP  - 44
EP  - 50
VL  - 8
IS  - 2
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2014.02.002
DO  - 10.1016/j.artres.2014.02.002
ID  - Jatoi2014
ER  -

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