Effects of Ti, Ti6Al4V, and Ti6Al7Nb on Osteoblast Bioactivity
- DOI
- 10.2991/meic-14.2014.316How to use a DOI?
- Keywords
- Ti;Ti6Al4V;Ti6Al7Nb; sandblasting and acid etching;bioactivity
- Abstract
The aim of this study was to investigate the surface morphology, hydrophilicity, and effects of sandblasted and acid-etched Ti, Ti6Al4V, and Ti6Al7Nb on the bioactivity of osteoblasts. The surfaces of Ti, Ti6Al4V, and Ti6Al7Nb were treated with Al2O3 sandblasting and a hydrochloric acid–sulfuric acid mixture to create etching. Surface morphology of samples was observed using scanning electron microscopy. The size of the contact angle was measured under a microscope using a measuring instrument. Osteoblasts from Sprague-Dawley rats were inoculated onto the surfaces of Ti, Ti6Al4V, and Ti6Al7Nb at a density of 1×104cells/ml. Cell morphology was observed using scanning electron microscopy. After sandblasting and acid etching, the surfaces of Ti, Ti6Al4V, and Ti6Al7Nb presented micron-size porous morphology and were hydrophilic. Cells spread significantly on the sandblasted and acid-etched surfaces of all three surfaces. Adhesion of osteoblasts was strongest on the surface of Ti6Al7Nb. Sandblasting and acid etching promoted bioactivity on all three surfaces, although sandblasted and acid-etched Ti6Al7Nb showed better bioactivity than Ti or Ti6Al4V. Overall, osteoblasts on the surface of Ti6Al7Nb exhibited better adhesion.
- Copyright
- © 2014, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Jingying Zhang AU - Ling Tang AU - Ying Guo AU - Weidong Ma PY - 2014/11 DA - 2014/11 TI - Effects of Ti, Ti6Al4V, and Ti6Al7Nb on Osteoblast Bioactivity BT - Proceedings of the 2014 International Conference on Mechatronics, Electronic, Industrial and Control Engineering PB - Atlantis Press SP - 1402 EP - 1405 SN - 2352-5401 UR - https://doi.org/10.2991/meic-14.2014.316 DO - 10.2991/meic-14.2014.316 ID - Zhang2014/11 ER -