Response of White Rat (Rattus Norvegicus) Leukocyte Numbers with Temulawak (Curcuma Xanthorrhiza Roxb) Extract in Severe Exercise

DOI

10.2991/978-94-6463-550-8_10How to use a DOI?

Keywords

Ginger Extract; Leukocyte Levels; Heavy Sports Activities

Abstract

Strenuous exercise can increase oxygen uptake in active muscle cells, which in turn can affect the number of leukocytes. Temulawak can prevent an increase in the number of leukocytes. The aim of this study was to analyze the effect of giving ginger extract on the number of leukocytes in male Wistar white rats (Rattus novergicus) with heavy exercise. This type of research was a pure experiment with a pretest-posttest with control group design on 28 rats that were given maximum physical activity and treated with ginger extract for 28 days. The test animals were divided into 4 groups, namely, the control group was not given ginger extract and 2 treatment groups were given ginger extract at doses of 6.75mg/day and 13.5mg/day. Statistical analysis uses the One way Anova test. There was no difference between groups before treatment (p=0.495) with the highest leukocyte count of 13.5 mg/day. There were differences between groups after treatment (p=0.039) with the highest leukocyte count in the control treatment. There was a difference between groups in delta (p=0.002) with the highest decrease in leukocytes in the 13.5 mg/day treatment. Temulawak extract has an effect on reducing the number of leukocytes. Giving ginger extract in the amount of 13.5 mg/day is the most effective dose in reducing the number of leukocytes.

Copyright

© 2024 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Ali Rosidi
AU  - Yuseli Hidayah
AU  - Zahra Maharani Latrobdiba
AU  - Yuliana Noor Setyawati Ulvie
AU  - Ari Istiany
AU  - Hersanti Sulistyaningrum
AU  - Enik Sulistyowati
PY  - 2024
DA  - 2024/10/27
TI  - Response of White Rat (Rattus Norvegicus) Leukocyte Numbers with Temulawak (Curcuma Xanthorrhiza Roxb) Extract in Severe Exercise
BT  - Proceedings of the 2nd Lawang Sewu International Symposium on Health Sciences: Nutrition (LSISHSN 2023)
PB  - Atlantis Press
SP  - 90
EP  - 96
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-550-8_10
DO  - 10.2991/978-94-6463-550-8_10
ID  - Rosidi2024
ER  -