Effects of Exposure to Phthalate Plasticizers in Food on Obesity
- DOI
- 10.2991/978-2-494069-31-2_186How to use a DOI?
- Keywords
- Phthalates; obesity; PPARγ; sirtuin
- Abstract
Phthalate (PAEs) is an environmental pollutant and can enter the human body through respiratory tract inhalation, skin contact, and food intake. As one of the food plasticizers, PAEs are seriously harming human health. They migrate into the food and enter the human body through the food packaging materials to affect the normal physiological metabolism of the human body. In this paper, we mainly describe how PAEs can induce obesity by interacting with nuclear receptors, inhibiting the expression of genetic epigenetic factor sirtuin, increasing the content of Bifidobacteria in the intestinal tract, and reducing the secretion of thyroid hormones (TH).Then, two feasible solutions were introduced. One was to control obesity by inhibiting peroxisome proliferator-activated receptor gamma (PPARγ) through celery oil seeds, and the other was to control obesity by supplementing Bifidobacterium longum APC1472 to improve intestinal microorganism. In conclusion, this article summarizes the latest progress in the mechanism of PAEs exposure to obesity.
- Copyright
- © 2022 The Author(s)
- Open Access
- Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.
Cite this article
TY - CONF AU - Honglin Yi PY - 2022 DA - 2022/12/29 TI - Effects of Exposure to Phthalate Plasticizers in Food on Obesity BT - Proceedings of the 2022 6th International Seminar on Education, Management and Social Sciences (ISEMSS 2022) PB - Atlantis Press SP - 1578 EP - 1584 SN - 2352-5398 UR - https://doi.org/10.2991/978-2-494069-31-2_186 DO - 10.2991/978-2-494069-31-2_186 ID - Yi2022 ER -