Effects of Penetration Enhancers for Transdermal Drug Delivery System and Methods Used for Them

DOI

10.2991/ifeesm-15.2015.120How to use a DOI?

Keywords

Transdermal penetration enhancers; Traditional Chinese medicine; Chemical synthesis penetration enhancers.

Abstract

Among methods used for transdermal penetration enhancement of drugs, the application of transdermal penetration enhancers is a method that has been most studied currently to promote the transdermal absorption of drugs, and also the most convenient method. Transdermal penetration enhancers (penetration enhancers) are defined as substances that you can accelerate the speed of the drug to penetrate the skin without severe irritation and damage to the skin. In this paper, the main mechanism of action and application methods of penetration enhancers for transdermal drug delivery system are comprehensively reviewed, which is expected to provide some helpful information for the relevant researchers. With the deepening of research on methods for the transdermal drug delivery system, more and more methods for the transdermal penetration enhancement have been learned. However, to look for safe and effective penetration enhancers for transdermal drug delivery system is still a research priority. Some new techniques for the detection and analysis are still required for elucidating structure-activity relationships and mechanism of action of the penetration enhancers, such as micro-dialysis and other methods. In addition, the synergistic effect of physical penetration enhancement method combined with chemical methods is also an important direction for the future research.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Guangyu Xu
AU  - Bin Zhao
AU  - Guanghong Wang
AU  - Manli Wang
PY  - 2015/09
DA  - 2015/09
TI  - Effects of Penetration Enhancers for Transdermal Drug Delivery System and Methods Used for Them
BT  - Proceedings of the 2015 International Forum on Energy, Environment Science and Materials
PB  - Atlantis Press
SP  - 633
EP  - 636
SN  - 2352-5401
UR  - https://doi.org/10.2991/ifeesm-15.2015.120
DO  - 10.2991/ifeesm-15.2015.120
ID  - Xu2015/09
ER  -