Status of Tuberculosis Infection and the Progression of HIV: Literature Study

DOI

10.2991/ahsr.k.220203.029How to use a DOI?

Keywords

Tuberculosis infection status; HIV; disease progression

Abstract

There are several factors that affect the development of HIV, one of which is TB co-infection. HIV and TB both play a role in reducing the function of the immune system. The aim of this study was to examine the relationship between the status of TB infection in HIV+ patients with the development/progression of HIV to AIDS and to observe the variation in the development/progression of HIV to AIDS in HIV+ patients who were co-infected with TB. Research articles were identified from the four databases Pub Med, BMC Public Health, Science Direct and Pro Quest. The review was undertaken to synthesize the findings in articles published between January 2010-October 2020 with the protocol and evaluation of the study using PRISMA. A total of 6 articles met the inclusion and exclusion criteria, consisting of 4 retrospective cohort studies and 2 prospective cohorts. The results of the analysis found that 4 articles discussed about TB/HIV with CD4 cells and all were significant. Two articles noted a decrease in CD4 cell count in the TB/HIV group and the other two found an increase in CD4 cell count. Although there was an increase, compared to the non-TB group, the total of CD4 in TB/HIV co-infected individuals tended to be lower. In viral load, two articles noted a decrease, but only one article mentioned a significant difference but did not compare it with the non-TB group. The progression of HIV to AIDS was noted in two articles and it was found that the risk of progression in the TB/HIV group was higher than in the non-TB group. TB infection in HIV patients affects the development of HIV through the interaction of the immune system. Further research on tuberculosis infection progressing from HIV to AIDS needs to examine the type or location of tuberculosis.

Copyright

© 2022 The Authors. Published by Atlantis Press International B.V.

Open Access

This is an open access article under the CC BY-NC license.

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TY  - CONF
AU  - Umi Solekhah
AU  - Rara Warih Gayatri
AU  - Tika Dwi tama
PY  - 2022
DA  - 2022/02/10
TI  - Status of Tuberculosis Infection and the Progression of HIV: Literature Study
BT  - Proceedings of the 5th International Conference on Sport Science and Health (ICSSH 2021)
PB  - Atlantis Press
SP  - 169
EP  - 178
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.220203.029
DO  - 10.2991/ahsr.k.220203.029
ID  - Solekhah2022
ER  -