Proceedings of the 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020)

Hypoglycemic Effect of Moringa oleifera Aqueous Extract in Diabetic Animal Studies: A Mechanisms Review

Authors
Dhigna Luthfiyani Citra Pradana, Eldiza Puji Rahmi, Annisa Farida Muti
Corresponding Author
Dhigna Luthfiyani Citra Pradana
Available Online 23 January 2021.
DOI
10.2991/ahsr.k.210115.117How to use a DOI?
Keywords
Moringa oleifera, aqueous extract, hypoglycemic, animal studies
Abstract

Diabetes is a chronic hyperglycemic condition which the therapy by maintaining blood glucose levels. Herbal plants can be an alternative therapy in reducing blood glucose levels. Indonesia is rich in herbaceous plants, one of which is Moringa oleifera Lam. Herbal plant of Moringa oleifera Lam. has been ethnopharmacology to reduce blood glucose levels. This review purpose of explaining the existing literature published until June 2020 on the mechanism of aqueous extract of Moringa oleifera leaves in hypoglycemic effect and their blood glucose levels in diabetic animal studies. Moringa oleifera aqueous extract was statistically significant in reducing blood glucose levels. The hypoglycemic mechanisms of Moringa oleifera aqueous extract inhibit the activity of Glucose Transporter Protein (GLUT2 and GLUT4), increases insulin secretion in pancreatic β-cells, and regenerating damaged pancreatic β-cells. This review provides evidence that an aqueous extract of Moringa oleifera leaves as a possible mechanism in reducing blood glucose levels in animal studies.

Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020)
Series
Advances in Health Sciences Research
Publication Date
23 January 2021
ISBN
978-94-6239-315-8
ISSN
2468-5739
DOI
10.2991/ahsr.k.210115.117How to use a DOI?
Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Dhigna Luthfiyani Citra Pradana
AU  - Eldiza Puji Rahmi
AU  - Annisa Farida Muti
PY  - 2021
DA  - 2021/01/23
TI  - Hypoglycemic Effect of Moringa oleifera Aqueous Extract in Diabetic Animal Studies: A Mechanisms Review
BT  - Proceedings of the 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020)
PB  - Atlantis Press
SP  - 620
EP  - 624
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.210115.117
DO  - 10.2991/ahsr.k.210115.117
ID  - Pradana2021
ER  -