Hypoglycemic Effect of Moringa oleifera Aqueous Extract in Diabetic Animal Studies: A Mechanisms Review
- DOI
- 10.2991/ahsr.k.210115.117How to use a DOI?
- Keywords
- Moringa oleifera, aqueous extract, hypoglycemic, animal studies
- Abstract
Diabetes is a chronic hyperglycemic condition which the therapy by maintaining blood glucose levels. Herbal plants can be an alternative therapy in reducing blood glucose levels. Indonesia is rich in herbaceous plants, one of which is Moringa oleifera Lam. Herbal plant of Moringa oleifera Lam. has been ethnopharmacology to reduce blood glucose levels. This review purpose of explaining the existing literature published until June 2020 on the mechanism of aqueous extract of Moringa oleifera leaves in hypoglycemic effect and their blood glucose levels in diabetic animal studies. Moringa oleifera aqueous extract was statistically significant in reducing blood glucose levels. The hypoglycemic mechanisms of Moringa oleifera aqueous extract inhibit the activity of Glucose Transporter Protein (GLUT2 and GLUT4), increases insulin secretion in pancreatic β-cells, and regenerating damaged pancreatic β-cells. This review provides evidence that an aqueous extract of Moringa oleifera leaves as a possible mechanism in reducing blood glucose levels in animal studies.
- Copyright
- © 2021, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Dhigna Luthfiyani Citra Pradana AU - Eldiza Puji Rahmi AU - Annisa Farida Muti PY - 2021 DA - 2021/01/23 TI - Hypoglycemic Effect of Moringa oleifera Aqueous Extract in Diabetic Animal Studies: A Mechanisms Review BT - Proceedings of the 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020) PB - Atlantis Press SP - 620 EP - 624 SN - 2468-5739 UR - https://doi.org/10.2991/ahsr.k.210115.117 DO - 10.2991/ahsr.k.210115.117 ID - Pradana2021 ER -