The Effect of Moringa Oleifera Leaf Extract on Mean Platelet Volume and Neutrophil-to-Lymphocyte Ratio in Autoimmune Patients
- DOI
- 10.2991/ahsr.k.210115.118How to use a DOI?
- Keywords
- Moringa oleifera extract, mean platelet volume, neutrophil-to-lymphocyte ratio, autoimmune patients
- Abstract
Background: Moringa oleifera is one of the promising novel treatments in autoimmune diseases through anti-inflammation and immunosuppression. Mean platelet volume and neutrophil-to-lymphocyte ratio are used to measure the degree of inflammation. This study aimed to identify the effect of Moringa oleifera leaf extract on the mean platelet volume and neutrophil-lymphocyte ratio in autoimmune patients. Research methods: This experimental study was conducted on 30 autoimmune patients consisting of 28 lupus patients and 2 rheumatoid arthritis patients of the rheumatology clinic at Moewardi General Hospital in January-March 2019. The patient was grouped into two, the treatment and control groups. The patients were in the treatment group received 2 grams of Moringa oleifera leaf extract per day, while those in the control group received a placebo. The study was conducted for 4 weeks, concluded with an evaluation. MPV (mean platelet volume) and NLR (neutrophil-to-lymphocyte ratio) examination used a haemocytometer. Statistical analysis was performed using paired T-test and independent T-test. The p-value was considered significant when p < 0.05. Results: The results showed that Moringa oleifera leaf extract decreases MPV (delta MPV = 4.141; r = 0.656; p- value = 0.02) and Neutrophil-to- lymphocyte ratio (delta NLR = 4.1391; r 0.489; p-value = 0.04). Conclusion: The study revealed that Moringa oleifera leaf extract decreased mean platelet volume and neutrophil-to-lymphocyte ratio in autoimmune patients.
- Copyright
- © 2021, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Nurhasan Agung Prabowo AU - Arief Nurudhin AU - Ayuningdyah Chitra Buanantri PY - 2021 DA - 2021/01/23 TI - The Effect of Moringa Oleifera Leaf Extract on Mean Platelet Volume and Neutrophil-to-Lymphocyte Ratio in Autoimmune Patients BT - Proceedings of the 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020) PB - Atlantis Press SP - 625 EP - 629 SN - 2468-5739 UR - https://doi.org/10.2991/ahsr.k.210115.118 DO - 10.2991/ahsr.k.210115.118 ID - Prabowo2021 ER -