Tuberculosis Treatment History Influenced Multidrug-Resistant Tuberculosis (MDR-TB) Incidence Based on Gene-Xpert Examination

DOI

10.2991/978-94-6463-070-1_5How to use a DOI?

Keywords

MDR-Tuberculosis; TB-treatment history; Gene Xpert

Abstract

Multidrugs Resistant-Tuberculosis (MDR-TB) caused by drugs resistant at least Isoniazid and Rifampicin Mycobacterium tuberculosis affects tuberculosis cases eradication efforts in the world. In 2014, 153 countries had reported MDR TB cases. MDR-TB can be caused by irregularity in taking medication tuberculosis drugs and categorized as TB-relapse, TB-failure, and TB-drop out.

Purpose To determine Tuberculosis treatment history influenced the incidence of Multidrugs-Resistant Tuberculosis (MDR TB). Methodology/Approach. Cross sectional studies in 88 TB-patients at dr. Ario Wirawan Hospital of Lung Salatiga examined by Gene Xpert MTB/RIF at August 2018 until March 2019. TB treatment history data obtained from TB-patients medical record. Findings. Eighty-eight TB patients showed 43 (48.8%) were 26–45 years old, 50 (56.8%) were men. TB treatment history was 38 (43.2%) relapse, 13 (14.8%) failed and 11 (12.5%) drop out. Gene Xpert’s examination results were 53 (60.2%) MDR TB Rifampicin resistant and 35 (39.7%) TB Rifampicin sensitive. Percentage of MDR TB Rifampicin resistant with history treatment TB Relaps were 25 (28.4%), Failed 9 (10.2%) and Drop out 11 (12.5%) and 8 (9.1%) for New-TB patient. TB treatment history influenced Multidrugs-Resistant Tuberculosis (MDR TB), p value 0.001, R value 0.228. Value/Implication – Regular awareness of taking medication tuberculosis drugs is important to avoid the incidence of MDR TB.

Copyright

© 2022 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Inayati
AU  - Qori’atul Putri Nurmala
AU  - Hasto Nugroho
PY  - 2022
DA  - 2022/12/26
TI  - Tuberculosis Treatment History Influenced Multidrug-Resistant Tuberculosis (MDR-TB) Incidence Based on Gene-Xpert Examination
BT  - Proceedings of the International Conference on Sustainable Innovation on Health Sciences and Nursing (ICOSI-HSN 2022)
PB  - Atlantis Press
SP  - 21
EP  - 27
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-070-1_5
DO  - 10.2991/978-94-6463-070-1_5
ID  - 2022
ER  -