Saliva as Diagnostic Medium to Detect Infectious Disease in Human Body: A Review

DOI

10.2991/978-94-6463-070-1_50How to use a DOI?

Keywords

bacterial; fungal; infection; saliva; viral

Abstract

Saliva is a oral biological fluid that has many benefits and has an function for maintaining oral health and can be clinically informative as a diagnostic media. Biomarkers in saliva are molecules that contain certain ingredients can be used to diagnose disease or assess the development and outcome of treatment. The characteristics of biomarkers make it feasible to be an alternative diagnostic media. The latest emerging technology has revealed medically that salivary biomarkers are important for detection many disease conditions such as cancer, viruses, bacteria, cardiac disease, autoimmune and metabolism disturbance. The purpose of this study is to determine the role of saliva as a diagnostic medium through its various biomarkers in saliva that can detect diseases caused by viral, bacterial and fungal infections in the body. This literature review of PubMed database was conducted without any limitation on date of publication to identify the potential of saliva as diagnostic medium of infectious diseases. Saliva has potential as medium diagnostic for ZIKA virus in the early week of symptom onset. High level of IgG can be detected in saliva of Helicobacter pylori bacterial infection in the body. Changes in salivary proteins such as calprotectin and histatin also have important diagnostic values in the detection of fungal infections. It can be concluded that saliva has potential as diagnostic medium that can be used in detecting various diseases caused by viral, bacterial and fungal infections.

Copyright

© 2022 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Dian Yosi Arinawati
AU  - Mitha Novianti
PY  - 2022
DA  - 2022/12/26
TI  - Saliva as Diagnostic Medium to Detect Infectious Disease in Human Body: A Review
BT  - Proceedings of the International Conference on Sustainable Innovation on Health Sciences and Nursing (ICOSI-HSN 2022)
PB  - Atlantis Press
SP  - 395
EP  - 404
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-070-1_50
DO  - 10.2991/978-94-6463-070-1_50
ID  - Arinawati2022
ER  -