Proceedings of the International Conference on Science Technology and Social Sciences – Physics, Material and Industrial Technology (ICONSTAS-PMIT 2023)

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Insights into Antibiofilm Mode of Actions of Natural and Synthetic Polymers: A Mini Review

Authors
Muhammad Hasif Yusri1, Nurul Hidayah Mohamad Nor2, Mohd Muzamir Mahat1, Rikson Siburian3, Mohd Fakharul Zaman Raja Yahya1, *
1Faculty of Applied Sciences, Universiti Teknologi MARA, Shah Alam, Selangor, Malaysia
2Low Dimensional Materials Research Centre, Faculty of Science, Universiti Malaya, Kuala Lumpur, Malaysia
3Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Medan, Indonesia
*Corresponding author. Email: fakharulzaman@uitm.edu.my
Corresponding Author
Mohd Fakharul Zaman Raja Yahya
Available Online 29 August 2024.
DOI
10.2991/978-94-6463-500-3_13How to use a DOI?
Keywords
Antibiofilm; Biofilm; Natural Polymers; Synthetic Polymers
Abstract

Pathogenic biofilms, which are organized and structured communities of microorganisms that adhere to surfaces and are enveloped in a polysaccharide and stringent extra-polymeric matrix, represent a challenging medical and industrial problem because of their remarkable recalcitrance towards conventional therapies. Natural and synthetic polymers offer promising strategies for biofilm control. This mini review discusses the antibiofilm efficacy of chitosan, β-peptides, polyhexamethylene biguanide, hyaluronic acid, alginate, poly(3,4-ethylenedioxythiophene), polyethylenimine, and epsilon-polylysine. These polymers inhibit biofilm formation by interfering with protein synthesis, altering mRNA expression, causing cell permeabilization, inducing DNA/RNA damage, interfering with negatively charged components of the biofilm matrix, and through chemodynamic and photothermal activities. These diverse mechanisms highlight the multifaceted approach required to combat biofilms effectively. The integration of these polymers into biofilm mitigation strategies holds significant promise for applications across healthcare, water treatment, and industrial maintenance, offering a robust solution to a persistent problem.

Copyright
© 2024 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the International Conference on Science Technology and Social Sciences – Physics, Material and Industrial Technology (ICONSTAS-PMIT 2023)
Series
Advances in Engineering Research
Publication Date
29 August 2024
ISBN
978-94-6463-500-3
ISSN
2352-5401
DOI
10.2991/978-94-6463-500-3_13How to use a DOI?
Copyright
© 2024 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Muhammad Hasif Yusri
AU  - Nurul Hidayah Mohamad Nor
AU  - Mohd Muzamir Mahat
AU  - Rikson Siburian
AU  - Mohd Fakharul Zaman Raja Yahya
PY  - 2024
DA  - 2024/08/29
TI  - Insights into Antibiofilm Mode of Actions of Natural and Synthetic Polymers: A Mini Review
BT  - Proceedings of the International Conference on Science Technology and Social Sciences – Physics, Material and Industrial Technology (ICONSTAS-PMIT 2023)
PB  - Atlantis Press
SP  - 134
EP  - 143
SN  - 2352-5401
UR  - https://doi.org/10.2991/978-94-6463-500-3_13
DO  - 10.2991/978-94-6463-500-3_13
ID  - Yusri2024
ER  -