Proceedings of the 4th International Conference on Life Sciences and Biotechnology (ICOLIB 2021)

Phytochemical Screening and Antimicrobial Activity of Cordyline fruticosa Leaf Infusion and Ethanol Extract Against Shigella dysentriae and Candida albicans

Authors
Vilya Syafriana1, *, Amelia Febriani1, Hera Ratnasari1
1Faculty of Pharmacy, National Institute of Science and Technology, Jakarta, 12640, Indonesia
*Corresponding author. Email: v.syafriana@istn.ac.id
Corresponding Author
Vilya Syafriana
Available Online 22 December 2022.
DOI
10.2991/978-94-6463-062-6_55How to use a DOI?
Keywords
Andong leaves; Diarrhea; Ethanol; Infusion; Maceration
Abstract

Cordyline fruticosa, also known to Indonesians as andong, is one of the simplest plants to grow. This plant is commonly used as an ornamental plant in yards, gardens, cemeteries, as well as a road barrier. Although it is primarily grown for ornamental purposes, the leaves of this plant empirically have been used to treat diarrhea and dysentery. The goal of this study was to determine what chemicals are present in andong leaves, as well as to see if an extract derived from the leaves has any activity against microbes that cause diarrhea, such as Shigella dysenteriae and Candida albicans. Andong leaves were extracted using two different methods, namely maceration with 96% ethanol as a solvent and infusion with distilled water heated to 90 ℃. Phytochemicals screening test was conducted qualitatively using the color-change reaction method. While antimicrobial activity test was performed using the disk diffusion method and continued with the Minimum Inhibitory Concentration (MIC) test using the solid dilution method. Phytochemicals screening revealed that the ethanol extract and infusion of andong leaves contained flavonoids, tannins, saponins, and phenols. The antimicrobial activity results showed that the ethanol extract and infusion of andong leaves inhibited the growth of S. dysenteriae but had no effect on C. albicans. These findings suggest that andong leaves have the potential to treat diarrhea caused by S. dysentriae, but not by C. albicans.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 4th International Conference on Life Sciences and Biotechnology (ICOLIB 2021)
Series
Advances in Biological Sciences Research
Publication Date
22 December 2022
ISBN
978-94-6463-062-6
ISSN
2468-5747
DOI
10.2991/978-94-6463-062-6_55How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

TY  - CONF
AU  - Vilya Syafriana
AU  - Amelia Febriani
AU  - Hera Ratnasari
PY  - 2022
DA  - 2022/12/22
TI  - Phytochemical Screening and Antimicrobial Activity of Cordyline fruticosa Leaf Infusion and Ethanol Extract Against Shigella dysentriae and Candida albicans
BT  - Proceedings of the 4th International Conference on Life Sciences and Biotechnology (ICOLIB 2021)
PB  - Atlantis Press
SP  - 539
EP  - 549
SN  - 2468-5747
UR  - https://doi.org/10.2991/978-94-6463-062-6_55
DO  - 10.2991/978-94-6463-062-6_55
ID  - Syafriana2022
ER  -