Electroencephalogram recording in Garut sheep: effect of the use of xylazine in small ruminants

DOI

10.2991/icoh-17.2018.38How to use a DOI?

Keywords

electroenchepalogram, xylazine, Garut sheep

Abstract

Minor procedures which are not painfull but require the animal to be relatively immobile may be performed with the aid of a sedative. In practical terms, sedative agent cause some degree of drowsiness until lost of consciousness. Xylazine used as a sedative and anaesthetic induction by inhibiting the release of norepinephrine in the brain, especially the locus coeruleus. Electroencephalogram (EEG) isa non-invassive procedureto record electrical activity from the scalp surface conduction media using metal electrodes. Garut sheep is an germ plasm asset of West Java and have a good potential to be developed as a source of meat, fighting sheep and laboratory animal in Indonesia. The aim of this study was to determine the condition of the brain electrical activity of Garut sheep by xylazine. Four healthy female Garut sheeps, age of 1-2 years old, 25-35kg body weight were used in this studies. They received xylazine bolus injection with a dose of 0.1 mg/kg body weight. Recording of the brain's electrical conduction was done using EEG. The placement of the electrodes on the head of sheep was performed at the point FP1-F7 and FP2-F2. Monitoring was conducted before induced and recording was done continuously starting before, during and after the induction of xylazine. Recorded data was collected for 60 minutes. The results showed that 15 minutes before injection brain waves presented gamma waves (30-70 Hz).However, one minutes after injection turned into beta waves (13-30 Hz) with a sharp wave morphology. Then 45 minutes later it entered the recovery phase, where the brain waves returned back to the gamma waves. These effect might occur that xylazine affect 2 receptors in locus coeruleus and it is involved the regulation of sleep or wakefulness.

Copyright

© 2018, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Dian Vidiastuti
AU  - Harry Soehartono
AU  - Deni Novianto
PY  - 2017/07
DA  - 2017/07
TI  - Electroencephalogram recording in Garut sheep: effect of the use of xylazine in small ruminants
BT  - Proceedings of the 1st International Conference in One Health (ICOH 2017)
PB  - Atlantis Press
SP  - 194
EP  - 198
SN  - 2468-5739
UR  - https://doi.org/10.2991/icoh-17.2018.38
DO  - 10.2991/icoh-17.2018.38
ID  - Vidiastuti2017/07
ER  -