Expression of IL-1 on Mucosal Cavity's Chronic Inflammation after Provision of Clarias Batrachus Fish Oil

DOI

10.2991/icoh-17.2018.12How to use a DOI?

Keywords

Chronic inflammation, IL-1, Fish oil Clariasbatrachus

Abstract

Background. The presence of cell or tissue damage always followed byinflammatory reactions. Inflammatory process should not persist because it can interfere even inhibit regeneration. An increased circulation of IL-1, IL-6 and TNF-alpha happens in chronic inflammation. IL-1 is granulocytes chemoattractant and has function to localize inflammation. Overexpression of IL-1 can inhibit wound healing so it needs currative treatment to decrease IL-1's expression. Purpose. To know expression of IL-1 after provision of Clariasbatrachus fish oil. Methods. We have used the post test only design in this research. There have been 19 Rattusnovergicus as research samples and those were divided into 3 groups, group 1 as control, group 2 has given 10% fish oil and group 2 has given 5% fish oil. Chronic inflammation treated to all samples for three days. The group 1 and 2 given Clariasbatrachusfish oil on the third day. We did decapitation on the fourth day to perform Immunohistochemistrystaining. The data were tabulated and analyzed statistically used Oneway ANOVA.Result. Group 2 and 3 has lower IL-1 expression than Control group.There is significant difference between groups. Conclusion. Clariasbatrachus Fish oil can lowered IL-1 expression onmucosal cavity's chronic inflammation.

Copyright

© 2018, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Theresia Indah Budhy
AU  - Istiati Istiati
AU  - Intan Vallentien Dwi Hariati
PY  - 2017/07
DA  - 2017/07
TI  - Expression of IL-1 on Mucosal Cavity's Chronic Inflammation after Provision of Clarias Batrachus Fish Oil
BT  - Proceedings of the 1st International Conference in One Health (ICOH 2017)
PB  - Atlantis Press
SP  - 52
EP  - 57
SN  - 2468-5739
UR  - https://doi.org/10.2991/icoh-17.2018.12
DO  - 10.2991/icoh-17.2018.12
ID  - Budhy2017/07
ER  -