Proceedings of the 2016 5th International Conference on Measurement, Instrumentation and Automation (ICMIA 2016)

Immobilization of lactase on modified magnetic chitosan microspheres

Authors
Qian Fang, Shujuan Jiang, Yang Yang, Yanfeng Tuo, Guangqing Mu
Corresponding Author
Qian Fang
Available Online November 2016.
DOI
10.2991/icmia-16.2016.161How to use a DOI?
Keywords
Immobilization, Lactase, Magnetic fluid, Lactase activity
Abstract

The immobilization of lactase is a more attractive approach to overcome the disadvantage of the free lactase. In the presented work magnetic Fe304 fluid was synthesized by chemical coprecipitation and its surface was modified with sodium oleate. Then the liquid paraffin was used as dispersant and glutaraldehyde as cross-linking agent to prepare modified chitosan magnetic microspheres with Fe3O4 as magnetic core and its outer coated with chitosan through the reversed-phase suspension polymerization method. Finally lactase was immobilized on modified chitosan magnetic microspheres by adsorption and crosslinking with glutaraldehyde. Results indicated the recovery of immobilized lactase was the highest when lactase was immobilized on the modified magnetic chitosan microspheres at 20 for 22 h and then reacted with 1.0 mL of 0.4% glutaraldehyde for crosslinking at 30 for 3 h, and a hydrolysis rate of 38% was obtained when the immobilized lactase was used to hydrolyze milk at 40 for 3h.

Copyright
© 2016, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2016 5th International Conference on Measurement, Instrumentation and Automation (ICMIA 2016)
Series
Advances in Intelligent Systems Research
Publication Date
November 2016
ISBN
978-94-6252-256-5
ISSN
1951-6851
DOI
10.2991/icmia-16.2016.161How to use a DOI?
Copyright
© 2016, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Qian Fang
AU  - Shujuan Jiang
AU  - Yang Yang
AU  - Yanfeng Tuo
AU  - Guangqing Mu
PY  - 2016/11
DA  - 2016/11
TI  - Immobilization of lactase on modified magnetic chitosan microspheres
BT  - Proceedings of the 2016 5th International Conference on Measurement, Instrumentation and Automation (ICMIA 2016)
PB  - Atlantis Press
SN  - 1951-6851
UR  - https://doi.org/10.2991/icmia-16.2016.161
DO  - 10.2991/icmia-16.2016.161
ID  - Fang2016/11
ER  -