The Research of AC-Pulse Iontophoresis Apparatus

DOI

10.2991/icismme-15.2015.251How to use a DOI?

Keywords

Iontophoresis; AC-pulse; Electroporation.

Abstract

Iontophoresis apparatus is a non-invasive device used to enhance the delivery of permeation across human epidermal membrane or extract endogenous substances from the body by applying a current across the membrane. This paper analyzes the transport theory of iontophoresis, and completes the whole frame design. It involved three points:1) an initial applied electroporation used to decrease the human skin electrical conductance to a target level.2)Utilize the one-chip computer to control the gain auto control circuit, make it produce a variable AC pluse, which can adjust by itself with the applying current to maintain the human skin electrical conductance at the target level during the transport study, and 3)a low voltage D.C. offset applied simultaneously with the AC to assist permeating transport. It is proved in the experiment that the skin resistance could keep constant due to the adjusting of the A.C. volt acted on the skin. Because the working current and the flux of the medicine can be constant if the skin resistance is constant, so this apparatus provide a new method for precise flux control therapy.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Man Su
AU  - Caixiang Yue
AU  - Lili Wang
PY  - 2015/07
DA  - 2015/07
TI  - The Research of AC-Pulse Iontophoresis Apparatus
BT  - Proceedings of the First International Conference on Information Sciences, Machinery, Materials and Energy
PB  - Atlantis Press
SP  - 1180
EP  - 1183
SN  - 1951-6851
UR  - https://doi.org/10.2991/icismme-15.2015.251
DO  - 10.2991/icismme-15.2015.251
ID  - Su2015/07
ER  -