Combination of Jamblang Leaf Extract (Syzygium cumini) and Vitamin C Increased Albumin and Decreased Bilirubin Serum Level on Lead Acetate Induced Rats
- DOI
- 10.2991/978-94-6463-431-0_7How to use a DOI?
- Keywords
- Syzigium cumini; vitamin C; albumin; bilirubin; lead acetate; rats
- Abstract
Oxidative stress from lead acetate can impair organ function. Antioxidants, which can be obtained from plants like Syzigium cumini, are necessary to counter oxidative stress. This study aimed to analyze the effect of the combination of jamblang leaf extract and vitamin C on serum albumin and bilirubin levels in lead-acetate-induced rats. This study was conducted on 35 rats divided into five groups: a negative control group (only given food and drink), a positive control group induced by lead acetate 40 mg/kg body weight, and treatment groups induced by lead acetate with three combination doses of jamblang leaf extract and vitamin C (35 mg/kg BW and 15 mg/kg BW; 75 mg/kg BW and 35 mg/kg BW; and 150 mg/kg BW and 75 mg/kg BW). Serum albumin and bilirubin levels were read with a spectrophotometer. The results showed that combination therapy of jamblang leaf extract with vitamin C increased albumin levels and reduced serum bilirubin levels after lead acetate administration significantly (p<0.05). This study concludes that the combination therapy of jamblang leaf extract and vitamin C affects serum albumin and bilirubin levels.
- Copyright
- © 2024 The Author(s)
- Open Access
- Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.
Cite this article
TY - CONF AU - Rauza Sukma Rita AU - Endrinaldi AU - Tofrizal PY - 2024 DA - 2024/05/30 TI - Combination of Jamblang Leaf Extract (Syzygium cumini) and Vitamin C Increased Albumin and Decreased Bilirubin Serum Level on Lead Acetate Induced Rats BT - Proceedings of selected papers of International Conference on Health, Science, and Environment (ICHSE 2023) PB - Atlantis Press SP - 55 EP - 62 SN - 2468-5747 UR - https://doi.org/10.2991/978-94-6463-431-0_7 DO - 10.2991/978-94-6463-431-0_7 ID - Rita2024 ER -